Head of Engineering

$125k - $200k

BiomeSense

Chicago, IL

Head of Engineering

Compensation: $125K– $200K salary, up to 1.0% equity stock options

Full benefits, including health coverage, PTO & parental leave

About BiomeSense

BiomeSense is a life sciences startup applying gut microbiome technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.

Role Summary

Own the full hardware (HW) lifecycle for GutLab, from architecture & subsystem integration through manufacturing, validation & deployment for a complex electromechanical device & BOM. Act as final technical authority for GutLab system performance, fleet stability & next generation GutLabs (Gen3) production, combining hands‑on engineering depth with strategic judgment to ensure current systems perform reliably in the field & Gen3 scales into manufacturing.

Key Responsibilities

System Ownership & Development: Own GutLab architecture (electromechanical & fluidic); lead design, testing & refinement via CAD, prototyping & manufacturing
Validation & Deployment Readiness: Own validation, stage gates, documentation & traceability across revisions, firmware & field performance. Lead troubleshooting, diagnostics & closed‑loop fixes to eliminate systemic failure modes
End-to-End Execution: Set & execute high standards for all aspects of HW development: procurement, transfer, sustaining engineering & operations
Manufacturing Scale‑Up: Drive DFM, design freeze, pilot builds, supplier alignment, cost targets & manufacturing strategy + execution for Gen3
Team Leadership: Mentor & lead a HW team; align resources, timelines & execution to production milestones
Strategic Problem Solving: Address any and all procurement challenges while identifying cost‑effective solutions
Cross‑Functional Collaboration: Partner with other leaders to align hardware development with broader company strategy & goals

Qualifications

8+ years’ experience in hardware engineering for complex electromechanical systems
Deep proficiency in CAD, tolerances, prototyping & manufacturing
Product lifecycle ownership (concept through transfer & scale‑up)
Proven ability to build & manage technical teams
Systems‑level troubleshooting expertise across mechanical, fluidic & electronic
Structured, decisive & execution‑oriented with high accountability
A strategic thinker who thrives under pressure in fast‑paced environments

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Vacancy posted 2 days ago

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