Director, Commercial Operations & Strategy

Why Join Us? Be a hero for our rare disease patients At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won't go - challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them. Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth - so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work. If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team. Position Summary: ultra innovative - Tackle rare and dynamic challenges Reporting to the VP, Global Commercial Operations & Strategy, the Director leads operationalization of Ultragenyx's global commercial governance model, with primary focus on global pricing governance and commercial planning. Scope: Global remit spanning North America, Latin America, EMEA, and APAC, covering in-line commercial products and pre-launch assets Accountable for enabling decision-making across pricing, forecasting, commercial analytics, portfolio prioritization, and distributor governance Operates across Commercial, Finance, Supply Chain, Market Access, and Regional organizations to drive enterprise alignment The role interfaces regularly with senior leadership through governance forums and executive materials, working in close partnership with function and Region teams. The role sits within a small, collaborative team that values clarity, pragmatism, and constructive problem-solving. The successful candidate will bring a solid grounding in pricing or market access and the appetite to broaden across commercial, the operational rigor to institutionalize governance forums, and the strategic judgment to facilitate thoughtful, high-impact decisions-and will be someone others genuinely want to work with on complex problems. Work Model: Flex: This role will typically require onsite work 2-3 days each week, or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite. Responsibilities: Own the operational leadership of the Pricing Operations Group - agenda-setting, decision framing, team coordination, materials, and executive escalation - in support of pricing decisions owned by Market Access and Commercial partners. Build and steward the global pricing tracker and reporting infrastructure, leading collection, validation, and reporting of pricing information with Regional and Market Access teams under disciplined controls on data sensitivity and access. Steward pricing corridor frameworks, approval thresholds, and exception management processes, and drive continuous improvement of pricing governance as the portfolio and geographic footprint evolve. Lead the operational cadence of the forecast consensus process and own the forecast assumptions log and change-control process, ensuring a single, traceable, and reconciled view of demand. Partner with Commercial, Finance, and Supply teams to improve forecast transparency, reconciliation quality, and organizational alignment. Lead ongoing operation of the Global Commercial KPI governance framework, in partnership with Finance, including metric definitions, ownership, calculation logic, data sources, cadence, and reconciliation rules. Partner with functions and Region teams to develop executive dashboards and performance narratives that connect data to business implications and recommended actions. Support enterprise investment and prioritization decisions through structured analyses, business cases, and executive decision materials, and assess the commercial implications of strategic alternatives and resource-allocation trade-offs. Partner with Regional teams and the VP, Global Commercial Operations & Strategy to design and stand up the global distributor governance framework, codifying performance standards, oversight cadence, escalation paths and best practice sharing. Requirements: Bachelor's degree in Business, Finance, Economics, Life Sciences, or related discipline. 10+ years of experience within the biopharmaceutical industry. Direct experience in Market Access and/or Pricing (including Pricing Operations), with demonstrated exposure to pricing governance or global pricing decision-making. Demonstrated ability to lead complex initiatives without direct authority in global, matrixed organizations. Strong analytical and financial acumen, including comfort with Power BI, Excel-based analytics, and executive reporting tools. Solution-oriented approach to ambiguous problems - with a demonstrated ability to move from problem identification to actionable path forward while maintaining constructive relationships Strong executive communication and presentation skills; ability to translate analysis into recommendations for senior leadership. Direct experience operating within global pricing governance frameworks (corridors, thresholds, exception management) Experience partnering with or working within Global Market Access, HEOR, or Pricing & Reimbursement functions, including launch pricing decisions for rare disease, specialty pharmaceutical, biotechnology, or gene therapy products Experience with commercial forecasting, business planning, performance management, product launch planning, and distributor-based commercial models Prior experience in management or strategy consulting with a life sciences focus (particularly in pricing, market access, or commercial excellence), combined with substantive biotech experience. #LI-CS1 #LI-Hybrid Pay Range $235,700-$291,200 USD Benefits Generous vacation time and public holidays observed by the company Volunteer days Long term incentive and Employee stock purchase plans or equivalent offerings Employee wellbeing benefits Fitness reimbursement Tuition sponsoring Professional development plans Benefits vary by region and country Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at View email address on click.appcast.io. See our CCPA Employee and Applicant Privacy Notice. See our Privacy Policy. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. #J-18808-Ljbffr Ultragenyx Pharmaceutical