SR. RESEARCH ASSOCIATE/ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT

Adicet Bio, Inc. is a clinical stage biotechnology company discovering and developing allogeneic gamma‑delta T cell therapies for autoimmune diseases and cancer. Adicet is advancing a pipeline of “off‑the‑shelf” gamma‑delta T cells, engineered with chimeric antigen receptors (CARs), to facilitate durable activity in patients. For more information, please visit our website at RESEARCH ASSOCIATE/ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT Key Responsibilities Coordinate and execute in vivo and ex vivo nonclinical studies to evaluate Adicet’s immune‑cell and gene‑therapy platforms, including efficacy, pharmacokinetic/pharmacodynamic, and safety assessments in relevant murine oncology and immunology models. Contribute to study design, experimental planning, timeline development, and data‑driven decision‑making to support program advancement. Collaborate and communicate effectively with cross‑functional teams and external contract research organizations to coordinate study execution, troubleshoot technical challenges, and ensure study endpoints align with program objectives. Perform necropsies and process tissues for downstream analyses, including flow cytometry, qPCR/ddPCR, and ELISA, to characterize pharmacologic activity and elucidate mechanisms of action. Maintain accurate, complete, and well‑organized experimental records in accordance with internal documentation and quality standards. Qualifications Bachelor’s degree in biological sciences or a related field with 5+ years of relevant R&D experience, or a Master’s degree with 3+ years of experience, preferably in immuno‑oncology, within an industry setting. Significant experience designing, executing, analyzing, and interpreting in vivo studies using murine xenograft disease models and/or humanized immunology models. Demonstrated proficiency administering therapeutic agents and establishing xenograft models through intravenous, intraperitoneal, and subcutaneous routes in mice. Strong technical proficiency in blood collection, including submandibular and tail‑vein sampling, as well as tissue necropsy and sample processing for flow‑cytometry applications. Experience with aseptic mammalian cell culture, including the maintenance and preparation of human cancer cell lines for nonclinical in vivo studies. Hands‑on experience with in vivo bioluminescence and/or fluorescence imaging, including image acquisition and data analysis using IVIS platforms. Experience with laboratory techniques such as flow cytometry, ELISA, qPCR/ddPCR, and cytokine bead‑based assays is preferred. Excellent organizational, communication, data‑analysis, and technical‑documentation skills. Demonstrated ability to work independently, troubleshoot scientific and technical challenges, and contribute innovative solutions. Ability to manage multiple priorities and thrive in a fast‑paced, collaborative, and supportive research environment. Employees are required to be onsite at least three days per week (Tuesday–Thursday mandatory). Some roles require full‑time onsite presence. Pay Range: $108,000—$150,000 USD We offer a competitive compensation package including base salary, annual cash bonus, long‑term incentives (equity), Employee Stock Purchase Plan (ESPP) and a 401(k) with ROTH and a 4.5% Company match. We also offer comprehensive health plans (medical, dental, vision, etc.), Flexible Health and Commuter Spending Accounts (FSA), a matched Health Savings Account (HSA), life, AD&D, short and long‑term disability insurance, and legal, pet, and other voluntary insurance programs. Generous paid time‑off is available, including 13 company holidays, paid end‑of‑year winter break, vacation, sick time, and paid parental leave. Adicet is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. #J-18808-Ljbffr Adicet Bio, Inc