Principal Investigator

Principal Investigator -Clinical Research

Relocation Assistance Available

Full-Time | On-Site

About the Opportunity

An established global clinical research organization is seeking an experienced physician to serve as the lead and sole Principal Investigator for its Springfield, Missouri research operation.

This is not a traditional study-level PI position. The physician will hold meaningful authority across the clinical research portfolio, leading their own trials while providing senior medical oversight, guiding research teams, and supporting additional PRN and contract investigators.

This is an opportunity to become the primary clinical leader within a sophisticated research environment and directly influence how trials are conducted.

Why Consider This Opportunity?

• Serve as the sole, senior Principal Investigator for the research operation
• Established clinical research program with decades of experience
• Broad exposure to Phase I-IV clinical trials
• Opportunity to mentor research staff and support other investigators
• High level of autonomy and physician leadership
• Collaboration with leading pharmaceutical and biotechnology sponsors
• Operate with meaningful autonomy within an established global organization
• Strong long-term career growth potential
• Relocation support available for qualified candidates

Key Responsibilities

• Serve as Principal Investigator for early-phase industry-sponsored clinical trials
• Ensure studies are conducted in accordance with ICH-GCP guidelines and protocol requirements
• Oversee participant safety, informed consent, and study conduct
• Review eligibility criteria and perform medical assessments
• Evaluate adverse events and ongoing participant safety
• Collaborate with sponsors, IRBs, monitors, and auditors
• Provide leadership and mentorship to clinical research staff
• Support overall study quality, regulatory compliance, and data integrity

Qualifications

• MD or DO
• Board Certified or Board Eligible (preferred but not required)
• Strong knowledge of ICH-GCP and clinical research regulations
• Experience in Endocrinology, Diabetes, Obesity, Metabolic Disease, Thyroid Disease, Internal Medicine, or related therapeutic areas preferred
• Strong interest in clinical research

If you are interested in learning more about this opportunity, please apply directly for a confidential discussion.