Sr. Principal Scientist, Kiro Science
$276.1k - $350kAmazon Locker
We are building the systems foundations for the next generation of autonomous coding agents, agents that operate in parallel, run for hours or days, and collaborate on codebases at a scale that breaks the assumptions of tools built for human developers. The hard problems in this space are no longer about model quality alone. They are about the systems layer underneath: how agents coordinate, how state is managed across long horizons, how correctness is preserved when many agents act concurrently, and how deterministic infrastructure can take on responsibilities that LLMs cannot reliably handle. Our team treats these as first-class research and engineering problems. We are designing new primitives for coordination, concurrency control, state management, validation, and inter-agent communication that move responsibility out of fragile LLM-mediated paths and into systems that are predictable, debuggable, and fast. Early prototypes have produced order-of-magnitude improvements in throughput and eliminated entire classes of integration-time failures that conventional architectures ship silently. The opportunity ahead is to define what the standard agent-systems stack looks like. Key job responsibilitiesKey job responsibilities- Develop breakthroughs in agentic architecture across areas such as autonomy, self-validation, continuous learning and timeseries foundation models.- Mentor and guide junior scientists.- Develop technology strategy and roadmap supporting product development- Develop prototypes for key technology, oversee the productization of the prototype, and develop critical assessment for the prototype- Write technical reports summarizing R&D progresses and communicate such progresses with stakeholdersBasic qualifications- PhD, or Master's degree in CS, CE, ML or related field experience- Experience programming in Java, C++, Python or related language- Experience in any of the following areas: AI (NLP or multi-modality models), Deep Learning, LLM model training, graph learning, software engineering.Preferred qualification - 15+ years of relevant, broad research experience after PhD degree or equivalent.- First author publications at Tier-1 ML conferences such as NeurIPS, ICLR, ICML, CVPR.Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company’s reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at .USA, CA, Santa Clara - 276,100.00 - 350,000.00 USD annuallyUSA, WA, Seattle - 240,100.00 - 324,800.00 USD annually
$264.1k - $350k
...technologists and multiple tier-1 services, we're seeking a Senior Principal Scientist to spearhead our AI research and development initiatives.... ..., enterprise-grade collaborative systems- Advancing the science of human-AI interaction in workplace environments- Creating...PrincipalSeniorFlexible hours$276.1k - $350k
We are looking for a science leader who is able to provide structure around complex business problems, work with machine learning scientists to estimate and validate their models on large scale data, and who can help business and tech partners turn the results of their...PrincipalSeniorLocal areaFlexible hours- Bristol-Myers Squibb is seeking a Senior Principal Scientist in Cancer Immunology at their Seattle location. The successful candidate will lead discovery teams in developing innovative cancer therapies and collaborate with external partners. Ideal applicants should possess...PrincipalSenior
- Dovetail Therapeutics is seeking a Senior/Principal Formulation Scientist to join our Seattle CMC team. You will lead formulation development for novel biologics, from preclinical screening through IND-enabling and into clinical manufacturing, while coordinating with internal...PrincipalSenior
- ...Dovetail Therapeutics is seeking a talented and motivated Senior/Principal Scientist to join our growing and dynamic team. If you are passionate... ...Knowledge and Skills Expertise in antibody and protein science, molecular biology, and biotherapeutic discovery Hands‑on experience...PrincipalSeniorFull time
- ...Dovetail is seeking a talented and experienced Senior / Principal Formulation Scientist, to join our growing and dynamic CMC team. You will advance... .... Qualifications and Skills: Degree in Pharmaceutical Sciences, Chemistry/Biochemistry, Biophysics, Chemical Engineering...PrincipalSenior
$121.48k - $166.73k
...resourceful Senior Epidemiologist who will conduct epidemiology analyses for science-based evaluations with a focus on human health risk. Candidate will work independently and also collaboratively with scientists in other disciplines (e.g., toxicologists, exposure scientists,...PrincipalSeniorWork at office$174.02k - $210.87k
## Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research CenterSeattle 400 Dexter - WA - USFind out how... ...in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient...PrincipalSeniorHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$198.9k - $269k
We are looking for a Principal Applied Scientist for Amazon Payments AI/ML Team, which contributes science and science-related engineering work for Amazon’s Payments Artificial Intelligence services (e.g. Amazon Payments Recommendation, Prediction, GEN AI platform to enable...PrincipalFlexible hours$198.9k - $269k
...knowledgeable, understands your preferences, and helps you find the right solution for your needs. As a Principal Applied Scientist on the team, you will help lead science innovation in our space across a large multidisciplinary team. You will have a breadth of problems to...PrincipalFlexible hours$218.8k - $295.9k
...technologies.The Sponsored Products and Brands team is seeking a Principal Applied Scientist to lead the development and implementation of generative... ...scientific communityBasic qualifications- PhD in Computer Science, Applied Mathematics, Statistics or a closely related...PrincipalFlexible hours- ...tasks—it will reason, plan, adapt, and act autonomously.As a Principal Applied Scientist, you'll help invent that future.You will lead the research... ...or equivalent research experience in Computer Science, Machine Learning, Artificial Intelligence, Statistics, Robotics...PrincipalWork at officeImmediate startRemote work
$198.9k - $269k
The Principal Applied Scientist will own the science mission for building next-generation proactive and autonomous agentic experiences across Alexa AI's Personalization, Autonomy and Proactive Intelligence organization. You will technically lead a team of applied scientists...PrincipalWorldwideFlexible hours- ...UiPath, and about our larger purpose.Could that be you?As a Principal Applied Scientist, you will lead the architecture, research, and... ...a technical leader and mentor across ML engineering, data science, and software engineering, fostering a culture of experimentation...PrincipalWork at officeImmediate startRemote work
$181.1k - $245k
...in building the future of AI-powered software development with Kiro, an intelligent development environment that revolutionizes how... .... You'll collaborate with world-class product, engineering, and science leaders while gaining exposure to state-of-the-art machine learning...PrincipalFlexible hours$198.9k - $269k
...in physical AI, working with world-class scientists and engineers, and seeing your... ...unprecedented scale.We are seeking an exceptional Principal Applied Scientist to drive technical... ...intelligence- Collaborate with multiple science and engineering teams to build adaptations...PrincipalWorldwideFlexible hours$198.9k - $269k
...the Prime subscription. Join our team of Scientists and Engineers developing AI/ML models to... ...across all touchpoints. We build the science and infrastructure that allows Prime to... ...optimized toward long-term member value.As a Principal Applied Scientist, you will be the...PrincipalFlexible hours$224k
...loyalty and traveler satisfaction.We are looking for a Principal Machine Learning Scientist to join our growing Travel Search & Discovery team. This... ...practicesMinimum Qualifications:PhD, or MS, in Computer Science, Machine Learning, Statistics, Engineering, or a related...PrincipalFull time$224k
...the team's technical directionMentor senior ML engineers and scientists, providing technical guidance on agentic design patterns, LLM... ...experimentation methodologyMinimum Qualifications:BS in Computer Science, Machine Learning, Statistics, Engineering, or a related field...PrincipalFull timeWorldwide$198.9k - $269k
As a Principal Applied Scientist, you are a trusted part of the technical leadership. You bring business and industry context to science and technology decisions. You set the standard for scientific excellence and make decisions that affect the way we build and integrate...PrincipalFlexible hours$198.9k - $269k
We are looking for a Principal Applied Scientist to own and advance the scientific vision for WorkSpaces Advisor — our agentic AI system that serves... ...concepts into actionable product strategy. Represent the science team in leadership forums and planning cycles.- Build and...PrincipalFlexible hours$228.7k - $309.4k
We are looking for a Principal Applied Scientist to drive the research and development of real-time multimodal conversational AI. You will operate... ...qualifications- PhD in Electrical Engineering, Computer Science, Mathematics, or a related technical field- 10+ years of industrial...PrincipalLocal areaFlexible hours$198.9k - $269k
...passionate to join an innovative team of scientists and engineers who use machine learning... ...Selection Success org is looking for a Principal Applied Scientist to lead us on our mission... ...qualifications- PhD in computer science, machine learning, engineering, or related...PrincipalFlexible hours$167.1k - $226.1k
Embark on an exciting science journey with International Emerging Stores Payments as we apply LLM techniques to improve the customer experience across multiple countries where we operate in. You will impact 1/4 of the world's population. Key job responsibilities1. Translate...SeniorFlexible hours$167.1k - $226.1k
We're looking for a senior scientist to lead the research direction for a system that gives AI persistent, compounding memory. This is a new problem space — not recommendation, not search, not summarization, though it draws from all three. The right scientist will define...SeniorFlexible hours$167.1k - $226.1k
...focused applied researcher to join our Pricing Optimization science group, with a charter to measure, refine, and launch customer... ...hardest pricing problems.A day in the lifeWe are hiring a Sr. Applied Scientist to drive our pricing optimization initiatives. We drive cross...SeniorFlexible hours$167.1k - $226.1k
Are you a scientist passionate about advancing Information Retrieval, NLP, and Large Language Models? Do you want access to massive datasets... ...and operational constraints - Mentor and raise the bar for the science team through design reviews, paper discussions, and...SeniorFlexible hours$167.1k - $226.1k
...team is looking for talented, motivated and passionate applied scientist to be part of the design and development of a highly scalable multi... ...scale of the web requires ideas from every area of computer science, including distributed computing, large-scale system design,...SeniorFlexible hours$167.1k - $226.1k
...in shaping the future of advertising!The Amazon Sponsored Products and Brands is looking for a talented Sr. Applied Scientist to join the Global Optimization science team at the forefront of advertising technology innovation. We are working backwards from emerging markets...SeniorWorldwideFlexible hours$167.1k - $226.1k
...and Generative AI (LLM) powered detection and resolution systems to help scale Amazon for years to come. We are seeking an Sr. Applied Scientist to join our team and help tackle challenging problems at the forefront of machine learning and artificial intelligence. Working...SeniorFlexible hours
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