Sr. Principal Scientist, Kiro Science
$276.1k - $350kAmazon Locker
We are building the systems foundations for the next generation of autonomous coding agents, agents that operate in parallel, run for hours or days, and collaborate on codebases at a scale that breaks the assumptions of tools built for human developers. The hard problems in this space are no longer about model quality alone. They are about the systems layer underneath: how agents coordinate, how state is managed across long horizons, how correctness is preserved when many agents act concurrently, and how deterministic infrastructure can take on responsibilities that LLMs cannot reliably handle. Our team treats these as first-class research and engineering problems. We are designing new primitives for coordination, concurrency control, state management, validation, and inter-agent communication that move responsibility out of fragile LLM-mediated paths and into systems that are predictable, debuggable, and fast. Early prototypes have produced order-of-magnitude improvements in throughput and eliminated entire classes of integration-time failures that conventional architectures ship silently. The opportunity ahead is to define what the standard agent-systems stack looks like. Key job responsibilitiesKey job responsibilities- Develop breakthroughs in agentic architecture across areas such as autonomy, self-validation, continuous learning and timeseries foundation models.- Mentor and guide junior scientists.- Develop technology strategy and roadmap supporting product development- Develop prototypes for key technology, oversee the productization of the prototype, and develop critical assessment for the prototype- Write technical reports summarizing R&D progresses and communicate such progresses with stakeholdersBasic qualifications- PhD, or Master's degree in CS, CE, ML or related field experience- Experience programming in Java, C++, Python or related language- Experience in any of the following areas: AI (NLP or multi-modality models), Deep Learning, LLM model training, graph learning, software engineering.Preferred qualification - 15+ years of relevant, broad research experience after PhD degree or equivalent.- First author publications at Tier-1 ML conferences such as NeurIPS, ICLR, ICML, CVPR.Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company’s reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at .USA, CA, Santa Clara - 276,100.00 - 350,000.00 USD annuallyUSA, WA, Seattle - 240,100.00 - 324,800.00 USD annually
$264.1k - $350k
...technologists and multiple tier-1 services, we're seeking a Senior Principal Scientist to spearhead our AI research and development initiatives.... ..., enterprise-grade collaborative systems- Advancing the science of human-AI interaction in workplace environments- Creating...PrincipalSeniorFlexible hours$276.1k - $350k
We are looking for a science leader who is able to provide structure around complex business problems, work with machine learning scientists to estimate and validate their models on large scale data, and who can help business and tech partners turn the results of their...PrincipalSeniorLocal areaFlexible hours- ...Virology - Principal Scientist / Senior Principal Scientist Location: Seattle, WA (onsite) Company: Venture-backed biotech (stealth mode... ...and scientific leaders in a small team where strong bench science directly informs decisions. Equal Opportunity Employer....PrincipalSeniorFull time
- Venture-backed biotech (stealth mode) in Seattle, WA is seeking a Principal Scientist/Senior Principal Scientist to lead and execute live-virus virology work as a hands-on player‑coach. You will expand live-virus neutralization capabilities, manage the viral strain library...PrincipalSenior
- Moonlight Bio, Inc. seeks a Senior/Principal Scientist for Process Development and CMC in Seattle. The role focuses on advancing cell therapy manufacturing, process characterization, and regulatory submissions while ensuring material supply continuity and strong collaboration...PrincipalSeniorFreelance
$175.17k - $183.69k
Senior Principal Scientist Job Summary Senior Principal Scientist at Bristol Myers Squibb in Seattle, WA. Wage range: $175,166 - $183,690. Responsibilities Use technical knowledge to support development of cellular drugs in the Chemical Manufacturing Control (CMC) program...PrincipalSeniorTemporary workWork experience placementSummer workRemote workFlexible hours2 days per week$121.48k - $166.73k
...resourceful Senior Epidemiologist who will conduct epidemiology analyses for science-based evaluations with a focus on human health risk. Candidate will work independently and also collaboratively with scientists in other disciplines (e.g., toxicologists, exposure scientists,...PrincipalSeniorWork at office$198.9k - $269k
We are looking for a Principal Applied Scientist for Amazon Payments AI/ML Team, which contributes science and science-related engineering work for Amazon’s Payments Artificial Intelligence services (e.g. Amazon Payments Recommendation, Prediction, GEN AI platform to enable...PrincipalFlexible hours$218.8k - $295.9k
...technologies.The Sponsored Products and Brands team is seeking a Principal Applied Scientist to lead the development and implementation of generative... ...scientific communityBasic qualifications- PhD in Computer Science, Applied Mathematics, Statistics or a closely related...PrincipalFlexible hours- ...tasks—it will reason, plan, adapt, and act autonomously.As a Principal Applied Scientist, you'll help invent that future.You will lead the research... ...or equivalent research experience in Computer Science, Machine Learning, Artificial Intelligence, Statistics, Robotics...PrincipalWork at officeImmediate startRemote work
$181.1k - $245k
...in building the future of AI-powered software development with Kiro, an intelligent development environment that revolutionizes how... .... You'll collaborate with world-class product, engineering, and science leaders while gaining exposure to state-of-the-art machine learning...PrincipalFlexible hours- ...UiPath, and about our larger purpose.Could that be you?As a Principal Applied Scientist, you will lead the architecture, research, and... ...a technical leader and mentor across ML engineering, data science, and software engineering, fostering a culture of experimentation...PrincipalWork at officeImmediate startRemote work
$198.9k - $269k
The Principal Applied Scientist will own the science mission for building next-generation proactive and autonomous agentic experiences across Alexa AI's Personalization, Autonomy and Proactive Intelligence organization. You will technically lead a team of applied scientists...PrincipalWorldwideFlexible hours$198.9k - $269k
...in physical AI, working with world-class scientists and engineers, and seeing your... ...unprecedented scale.We are seeking an exceptional Principal Applied Scientist to drive technical... ...intelligence- Collaborate with multiple science and engineering teams to build adaptations...PrincipalWorldwideFlexible hours$198.9k - $269k
...the Prime subscription. Join our team of Scientists and Engineers developing AI/ML models to... ...across all touchpoints. We build the science and infrastructure that allows Prime to... ...optimized toward long-term member value.As a Principal Applied Scientist, you will be the...PrincipalFlexible hours$198.9k - $269k
...searching for products" to "being understood as a person."As a Principal Applied Scientist, you will be the intellectual engine behind this transformation. You will define the frontier, architect the science strategy for a large, multidisciplinary organization, and...PrincipalImmediate startFlexible hours$198.9k - $269k
...chain and fulfillment to Amazon and use Amazon's world-class science, technology, and logistics infrastructure to deliver... ...strategic importance. The FBA organization is looking for a Principal Applied Scientist with deep expertise in Operations Research, Reinforcement...PrincipalWorldwideFlexible hours$198.9k - $269k
...to make that team measurably faster.We are looking for a Principal Applied Scientist to own the scientific direction of that work. This is a broad... ..., retrieval, agentic behavior, and the measurement science needed to know whether any of it is working. You will not...PrincipalLocal areaFlexible hoursDay shift$198.9k - $269k
...adopt and easy to use.The TeamJoin the next science revolution at AWS Life Sciences Applied... ...where you'll work alongside world-class scientists to build AI that transforms how... ...team.The RoleWe are seeking an exceptional Principal Applied Scientist to set the scientific...PrincipalImmediate startWorldwideFlexible hours$198.9k - $269k
We are looking for a Principal Applied Scientist to own and advance the scientific vision for WorkSpaces Advisor — our agentic AI system that serves... ...concepts into actionable product strategy. Represent the science team in leadership forums and planning cycles.- Build and...PrincipalFlexible hours$159.1k
...Excellent skills in problem solving, programming, and computer science fundamentals. ~ Solid background in statistics, math, CS, machine... ..., and computer vision or NLP. DESCRIPTION Are you a scientist interested in pushing the state of the art in Generative AI,...Principal- ...generation of AI-powered products to build. We are an applied science organization building the science behind them. The work... ...systems running in industrial environments. As Principal Applied Scientist, you lead the science on a major capability area inside the...Principal
- Bristol Myers Squibb seeks a Principal Scientist to join the Cellular Therapy Translational Biology Research group in Seattle, WA, driving non-clinical development strategies across oncology and autoimmune indications. You will conduct mechanism studies, biomarker identification...Principal
$198.9k - $269k
...passionate to join an innovative team of scientists and engineers who use machine learning... ...Selection Success org is looking for a Principal Applied Scientist to lead us on our mission... ...qualifications- PhD in computer science, machine learning, engineering, or related...PrincipalFlexible hours- AWS Applied AI Solutions (AAIS) in Seattle is seeking a Principal Applied Scientist to own the scientific direction of AI capabilities across knowledge... ...contributing to production systems. The role emphasizes science leadership, collaboration, and rigorous evaluation, with a...Principal
- Amazon Science in Seattle is seeking a Principal Applied Scientist to own the scientific direction of knowledge-driven AI systems. This leadership role guides a team of applied scientists and MLEs, while staying hands-on to prototype ideas on real data. You will define...Principal
$167.18k - $226.24k
...generation of AI-powered products to build. We are an applied science organizationbuildingthe science behind them. The work sits... ...systems running in industrial environments. As Principal Applied Scientist, you lead the science on a major capability area inside the...PrincipalLocal area$167.1k - $226.1k
Embark on an exciting science journey with International Emerging Stores Payments as we apply LLM techniques to improve the customer experience across multiple countries where we operate in. You will impact 1/4 of the world's population. Key job responsibilities1. Translate...SeniorFlexible hours- Bristol Myers Squibb's Cellular Therapy Translational Biology Research group in Seattle, WA, seeks an experienced Principal Scientist to lead laboratory-based translational studies across oncology and autoimmune indications. You will design experiments, generate data to...Principal
$167.1k - $226.1k
We're looking for a senior scientist to lead the research direction for a system that gives AI persistent, compounding memory. This is a new problem space — not recommendation, not search, not summarization, though it draws from all three. The right scientist will define...SeniorFlexible hours
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