Senior MES Engineer
$145k - $180kMacpower Digital Assets Edge
Job Summary:
Salary: $145,000-$180,000 base + uncapped bonus
Travel Requirement: Up to 25%
Key Responsibilities:
- Requires demonstrated technical proficiency in MES software design and configuration.
- Must have experience integrating MES with Level 2 and Level 4 systems.
- Responsible for leading a team of engineers to deliver MES solutions.
- Directly interacts with customers to gather requirements and deliver full project life cycle execution.
- This is a leadership role requiring strong problem-solving skills, interpersonal skills, business acumen, and relationship building.
- Success is demonstrated by securing repeat business from both new and existing clients.
Salary: $145,000-$180,000 base + uncapped bonus
Travel Requirement: Up to 25%
Key Responsibilities:
- Design and deliver MES solutions and standards independently or by leading a team.
- ct as a solution architect to conceptualize, detail, and implement MES systems.
- Develop MES strategies that integrate process knowledge, equipment, quality standards, and IT systems.
- Improve uptime, regulatory compliance, and process efficiency.
- Lead project management activities such as planning, budgeting, scheduling, task prioritization, tracking, and reporting.
- Manage project execution, financials, team communication, and profitability (up to $1M).
- Lead status meetings and provide regular updates.
- Oversee daily operations of assigned projects.
- ct as a technical lead and guide junior engineers and technicians.
- May serve as Project Manager for smaller-scale projects.
- Bachelor's degree in Engineering, Computer Science, or Applied Sciences is required.
- More than 10 years of MES experience is preferred.
- Proven deployment experience with Werum Client-X, Sepasoft, or POMS.
- Experience across full MES lifecycle: concept, design, implementation, testing, start-up, and commissioning.
- Life Sciences industry experience required.
- Familiarity with regulations such as cGMP and 21 CFR Part 11.
- Proficient in developing integrated EBR recipes using GAMP5, ISA-88 (S88), and ISA-95 (S95) standards.
- Strong understanding of manufacturing processes and MES system configuration.
- Knowledge of GMP warehouse and inventory management.
- Experience with external interfaces like DeltaV, SAP, LIMS, PI, and Maximo.
- Strong knowledge of historian and reporting systems.
- Experience with SQL, Oracle, or other relational databases.
- Knowledge of IT/OT networking.
- Strong technical writing and verbal communication skills.
- Proficiency in MS Office applications.
- Demonstrated experience leading MES project teams.
- Experience mentoring junior engineers.
- ble to provide professional references (subordinate, peer, manager).
- Willingness to travel up to 25%.
- Must be able to see, hear, speak clearly, and use hands dexterously.
- Requires driving, lifting, mounting/dismounting equipment, pushing, and pulling.
- Standard office, client site, and industrial environments.
- Frequent use of computers, printers, copiers, and phones.
- Phone screen with Talent Advisor.
- First technical interview (video).
- Final onsite technical interview.
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior MES Engineer in Raleigh, NC vacancy
- ...About the job Senior MES Engineer Senior MES Engineer needs 10+ years experience Senior MES Engineer requires: MES solution deployment experience with but not limited to Werum PAS-X, Sepasoft, or POMS Proven experience with all phases of MES projects...Senior
- ...ATS Company: PA Solutions Requisition ID: 16598 Location: Raleigh, NC, US, 27603 Date: Oct 10, 2026 Senior MES Engineer Your responsibilities We are seeking a Senior MES Engineer to support the expansion of our Manufacturing Execution Systems (MES) practice...SeniorRemote work
- ...About the job Senior MES Engineer Summary The Senior MES Engineer will lead design, configuration, implementation, and commissioning of Manufacturing Execution System (MES) solutions with integration to Level 2 and Level 4 systems. Acting as a solution architect...SeniorWork at office
- ...Senior Mes Engineer This position requires demonstrated technical proficiency in software design and configuration of MES solutions with integration capabilities to level two and four systems. The Senior MES Engineer will interact directly with the customer and lead...SeniorWork at office
$93k - $120.75k
...RoleWe are seeking an experienced technical contributor to join our Automation Systems Engineering team at the Biogen RTP Bio site. The Senior Automation Engineer I will support Syncade (MES) system administration within a GMP-regulated manufacturing environment. This role...SeniorFull timeTemporary workLocal area$145k - $180k
...Job Description Job Description Description: Senior MES Engineer | $145K-$180K + Bonus Raleigh, NC | Hybrid | Life Sciences MES / Industrial Automation Elizabeth Banzhaf, LPN Co-Founder & COO | Heartline Staffing Call or Text: (***) ***-**** LinkedIn:...SeniorLive inWork at officeHome officeVisa sponsorshipRelocation package- ATS Company: PA SolutionsSenior
- ...Description: We are seeking an experienced Senior Validation Specialist to lead... ...internal/external audits. Collaborate with Engineering, Quality Assurance, Manufacturing, Automation... ...Preferred Qualifications: Experience with MES, LIMS, SCADA, PLC, ERP, or other GMP computerized...Senior
$116k - $258k
...analytical solutions, and OneSource services.Job TitleSenior Automation Engineer (cGMP) - Project FarmaLocation(s)Customer Site - AL, Customer... ...-level experience with one or more aspects of Process Control, MES and Digital Systems platforms. Willingness to travel as required...SeniorFull timeRemote workWork visa$100k - $130k
...development of groundbreaking therapies. Our mission is to be the engine of innovation for genomic medicine pioneers. As a member of our... ...the Danaher Business System which makes everything possible.The Senior Engineer, Process Validation is responsible for leading &...SeniorFull timeRemote workWork from homeFlexible hours- ...minds to help shape it. If you’re ready to help define what comes next, we’d love to meet you. Position Summary: As Senior Gameplay Engineer, you are a versatile engineer who thrives in a collaborative environment and deeply enjoys empowering designers. You will...SeniorWork at officeRelocation
- ...benefits.This position is seeking an experienced and adaptable engineer to join the Grid Strategy & Advancement Engineering Application... ...procedures to work that is progressively complex and varied.The Senior Engineer manages work in engineering areas of specialization,...SeniorFull timeRemote workVisa sponsorshipRelocation package
- ...Virtual Design and Construction Senior Engineer Clayco is a full-service, turnkey real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across North America the highest quality solutions on time, on budget...SeniorFor contractorsFor subcontractorRelocationFlexible hours
- ...resilient communities and quality of life. We bring together planners, engineers, architects, construction management staff, environmental,... ...that connects employees around the world.HDR is looking for a Senior Rail Engineer to join our Transportation Business Group in...SeniorLocal area
- Reference: PR/598654_1791205236Senior Quality Engineer - New Product Introduction (NPI)Position OverviewLocation: within a 1 hour drive south of Raleigh, NC We are seeking a Senior Quality Engineer to join our growing team and play a critical role in driving quality excellence...Senior
- ...environment where personal and professional growth are prioritized.For this position we are looking for highly skilled electrical engineers to develop cutting-edge technology for the United States Department of Defense within our Military Embedded Systems and Applications...SeniorFull time
- DescriptionThe Senior Substation Engineer will lead the preparation of design deliverables for new and modified high-voltage (13kV to 765kV) electrical power substation projects. The Senior Substation Engineer will work with the project team through the design and construction...SeniorWork at office
$155.6k - $306.8k
Position Summary At Deloitte, Forward Deployed Engineers (FDE) don’t just build AI solutions, they help clients turn AI ambition... ...Recruiting for this role ends on 10/30/2026. Work you’ll do As a Senior ServiceNow FDE, you will work side by side with senior...SeniorLocal areaShift work- ...higher education, K-12 schools, infrastructure, and more.As our project backlog continues to grow, we are seeking a Senior Mechanical Project Engineer to join our Healthcare Mechanical Department in Raleigh, NC.In this pivotal role, you will provide essential technical...SeniorContract workFor contractorsWork at officeLocal area
- DescriptionA Senior Electrical Designer will lead various phases of planning, site evaluations, analytical designs, design documents... ...diagrams, and relay panel schematics under the direction of the engineer.Incorporate schedules, budgets and project criteria into electrical...Senior
- ...not have to choose between living life and making a living. Live your best life with Merz Aesthetics.A Brief OverviewThe Senior Electrical Engineer will lead the design, development, and analysis of electronic hardware and embedded firmware for both new and existing products...SeniorFull time
- ...owned firm? Wiley|Wilson, with 190+ employee-owners across five offices, is looking for the right person to grow with us!As a Senior Civil Engineer, you'll lead the design of complex land development and infrastructure projects, serving federal government clients. These...SeniorLocal areaWork from home
$160k - $240k
...application due to a disability, contact this employer to ask for an accommodation or an alternative application process. Senior Roadway Engineer Full Time Raleigh, NC, US 2 days ago Requisition ID: 3475 At Whitman, Requardt & Associates, LLP, we are "People...SeniorFull timeContract workTemporary workH1bWork at officeLocal areaFlexible hours- .... Petersburg. This position provides technical leadership and engineering expertise supporting the evaluation, qualification, and deployment... ...4 years’ engineering experienceBasic/Required Qualifications Senior EngineerBachelor’s degree in engineering from an ABET-...SeniorFull timeFor contractorsVisa sponsorshipRelocation package
$165k - $230k
...Job Description Power Systems Engineers - Senior to Principal Level \n (Microgrids, Data Centers, BESS) \n Compensation: $165,000 – $230,000 (Base + Bonus) \n Locations: Raleigh, NC & Milwaukee, WI \n \n Power Technology Associates, Inc. is conducting a...Senior- ...7Company Name:HITACHI ENERGY USA INCProfession (Job Category):Engineering & ScienceJob Schedule: Full timeRemote:NoJob Description:English... ...à la recherche d’un(e) Ingénieur(e) principal(e) de projet (Senior Project Lead Engineer) pour assumer la responsabilité technique...SeniorFull timeLocal areaFlexible hours
- ...Sr. Principal Mechanical Engineer TARGAN is seeking a highly accomplished Sr. Principal Mechanical Engineer to serve as a senior technical leader within our R&D and Engineering organization. This individual will play a critical role in the invention, architecture,...SeniorWork at officeFlexible hours
$165k
...Required Education & Experience: ~ Bachelor’s degree in Electrical Engineering. ~9+ years of progressive experience in the AEC industry, with a healthcare facilities or university/higher learning institution focus. ~ Expertise with engineering software platforms...SeniorRelocation package$155k - $185k
...and desire to positively impact the environment and lives of others in a refreshing, vibrant, and inclusive culture.The Senior Mechanical Design Engineer will provide senior technical ownership for the architecture and mechanical design of narrowbody high-lift devices....SeniorFull timeTemporary workWork at officeLocal areaRemote work$120k - $160k
DescriptionKforce has a client in Raleigh, NC that is seeking a Senior Electrical Control Systems Engineer (P.E.) to lead Electrical, Instrumentation & Controls (EI&C) projects supporting municipal and industrial facilities. This role will serve as a technical leader responsible...SeniorRemote work
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior MES Engineer. Be the first to apply!
Related searches
- senior living Raleigh, NC
- senior associate vice president Raleigh, NC
- senior app developer Raleigh, NC
- senior data analyst Raleigh, NC
- senior application support engineer Raleigh, NC
- senior manager data analytics Raleigh, NC
- senior revenue accountant Raleigh, NC
- senior devops Raleigh, NC
- senior supply chain manager Raleigh, NC
- senior internal audit Raleigh, NC



