Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist

ClinLab Solutions Group

Job Title: Job Title: Principal Scientist

Work Location: Frederick County, Maryland

Summary:

Seeking an experienced scientist to lead and mentor laboratory teams, design and implement advanced cell-based assays, and drive technical excellence in flow cytometry and related methodologies. This role requires strong leadership, technical expertise, and the ability to communicate scientific findings through reports, publications, and presentations.

Responsibilities:

  • Mentor, coach, and train laboratory team members, set priorities, and collaborate with other leaders to ensure efficient lab operations.
  • Design and implement complex cell-based assays, including flow immunophenotyping and primary cell-based assays, tailored to project requirements.
  • Develop, write, and implement standard operating procedures (SOPs) to ensure regulatory compliance and high-quality assay performance.
  • Perform cell assays using established SOPs, such as flow immunophenotyping and ELISpot, and troubleshoot technical issues as needed.
  • Generate technical reports, posters, papers, and white papers for client communications, conferences, and peer-reviewed journals.
  • Train scientific and technical staff in laboratory procedures, data review, and presentation, ensuring competency and adherence to safety standards.
  • Track and analyze laboratory efficiency and quality metrics, maintaining a safe and productive work environment.
  • Act as a technical expert and thought leader, staying current with industry trends and advising management on key scientific and operational matters.

Qualifications:

  • Ph.D. in life sciences or a relevant field (preferably Immunology or Cellular Biology).
  • At least 8 years of full-time post-doctoral laboratory experience.
  • Strong bench scientist skills in cell-based assays, with hands-on flow cytometry experience required; experience with ELISpot and other cell-based assays preferred.
  • Proficiency in standard biology laboratory techniques, including cell isolation and primary cell-based assays.
  • Experience with cell sorting, troubleshooting, client relationships, and managing project timelines.
  • Experience in validation/qualification of assays to CAP/CLIA/GLP or ISO guidelines.
  • Strong organizational and communication skills, with experience generating technical reports.
  • Ability to differentiate colors across the full spectrum and meet physical requirements (lifting, dexterity, exposure to cold environments).
  • Fluency in reading, writing, and speaking English.
  • 10-15+ years' experience in a core laboratory with leadership responsibilities over a flow cytometry team preferred.
  • Industrial experience and/or management of external collaborations is desirable.
  • Experience with viral infections, cell culture, cell line derivation, nucleic acid extraction from primary human samples, and nucleic acid characterization techniques preferred.

Please make an application promptly if you are a good match for this role due to high levels of interest.

Work Location: Frederick County, Maryland

Summary:

Seeking an experienced scientist to lead and mentor laboratory teams, design and implement advanced cell-based assays, and drive technical excellence in flow cytometry and related methodologies. This role requires strong leadership, technical expertise, and the ability to communicate scientific findings through reports, publications, and presentations.

Responsibilities:

  • Mentor, coach, and train laboratory team members, set priorities, and collaborate with other leaders to ensure efficient lab operations.
  • Design and implement complex cell-based assays, including flow immunophenotyping and primary cell-based assays, tailored to project requirements.
  • Develop, write, and implement standard operating procedures (SOPs) to ensure regulatory compliance and high-quality assay performance.
  • Perform cell assays using established SOPs, such as flow immunophenotyping and ELISpot, and troubleshoot technical issues as needed.
  • Generate technical reports, posters, papers, and white papers for client communications, conferences, and peer-reviewed journals.
  • Train scientific and technical staff in laboratory procedures, data review, and presentation, ensuring competency and adherence to safety standards.
  • Track and analyze laboratory efficiency and quality metrics, maintaining a safe and productive work environment.
  • Act as a technical expert and thought leader, staying current with industry trends and advising management on key scientific and operational matters.

Qualifications:

  • Ph.D. in life sciences or a relevant field (preferably Immunology or Cellular Biology).
  • At least 8 years of full-time post-doctoral laboratory experience.
  • Strong bench scientist skills in cell-based assays, with hands-on flow cytometry experience required; experience with ELISpot and other cell-based assays preferred.
  • Proficiency in standard biology laboratory techniques, including cell isolation and primary cell-based assays.
  • Experience with cell sorting, troubleshooting, client relationships, and managing project timelines.
  • Experience in validation/qualification of assays to CAP/CLIA/GLP or ISO guidelines.
  • Strong organizational and communication skills, with experience generating technical reports.
  • Ability to differentiate colors across the full spectrum and meet physical requirements (lifting, dexterity, exposure to cold environments).
  • Fluency in reading, writing, and speaking English.
  • 10-15+ years' experience in a core laboratory with leadership responsibilities over a flow cytometry team preferred.
  • Industrial experience and/or management of external collaborations is desirable. xhyhwjd
  • Experience with viral infections, cell culture, cell line derivation, nucleic acid extraction from primary human samples, and nucleic acid characterization techniques preferred.

Vacancy posted 6 hours ago
Similar jobs that could be interesting for youBased on the Principal Scientist in Frederick, MD vacancy
  • Precision Medicine Group seeks a Principal Scientist to lead immunophenotyping and translational medicine projects for biopharmaceutical clients. You will mentor staff, design advanced flow cytometry assays and receptor occupancy tests, and ensure GLP/CLIA-compliant execution... 
    Principal

    Precision for Medicine

    Frederick, MD
    3 days ago
  • $130k - $200k

     ...and have not been approved for any indication. Position Overview Tonix is seeking a highly motivated and innovative Principal Scientist with a background in immunology, autoimmunity or oncology to contribute to research and development across our growing immunology... 
    Principal
    Temporary work
    Work experience placement
    Local area
    Flexible hours

    Tonix Pharmaceuticals

    Frederick, MD
    4 days ago
  • $110.7k - $166.1k

     ...Category: Division: Precision for Medicine Business Unit: Translational Sciences Requisition Number: 7194 Position Summary The Principal Scientist will be instrumental in helping Precision achieve its goals of delivering exceptional services to Precision’s diverse,... 
    Principal
    Full time
    Contract work
    Local area

    Precision for Medicine

    Frederick, MD
    1 day ago
  •  ...Cell Therapy Research Scientist / Senior Research Scientist Location: Frederick, MD Schedule: Full-Time | Monday–Friday | First Shift Work Arrangement: Onsite Position Overview We are seeking a highly motivated Cell Therapy Research Scientist / Senior Research... 
    Suggested
    Full time
    Local area
    Monday to Friday
    Day shift

    Kelly

    Frederick, MD
    5 days ago
  • $125.1k - $225.2k

     ...achieve your full potential. Unleash your talent and redefine what’s possible.Job Description:Parsons is seeking a Senior Research Scientist - Genomics and Infectious Diseases to support the Biological Defense Research Directorate within the Naval Medical Research... 
    Suggested
    Full time
    Contract work
    For contractors
    Flexible hours
    Afternoon shift

    Parsons

    Frederick, MD
    4 days ago
  • Precision Medicine Group in Frederick, MD is seeking a skilled flow cytometry expert to perform assays, validate procedures, and support SOP development. You will design experiments, analyze data, and present results with high quality output. The role requires a Master’...

    Precision Medicine Group

    Frederick, MD
    1 day ago
  • Precision Medicine Group seeks a skilled bioanalytical scientist to support commercial clients through accurate data analysis using Softmax, MSD, Prism, and Excel. You will perform immunoassays, DNA/RNA handling, and reagent preparation in a GLP-compliant lab in Frederick... 

    Precision Medicine Group

    Frederick, MD
    2 days ago
  • General Dynamics Information Technology (GDIT) seeks an experienced Senior Human Subjects Protection Scientist to support the ORRC/OHRO within DHA R&D. The role ensures DHA-conducted and sponsored research complies with Federal, DoD, FDA, and international requirements.... 

    General Dynamics Information Technology

    Frederick, MD
    4 days ago
  • Scientist II, Stem Cell Lab (IPSC)Job ID: req4635Employee Type: exempt full-timeDivision: Laboratory Animal Science ProgramFacility: Frederick: Ft DetrickLocation: PO Box B, Frederick, MD 21702 USAThe Frederick National Laboratory is operated by Leidos Biomedical Research... 
    Full time
    Part time
    Traineeship
    Work at office

    Frederick National Laboratory for Cancer Research

    Frederick, MD
    3 days ago
  •  ...Job Description Job Description Description:   Senior Regulatory Affairs Scientist   Venesco LLC is seeking a Senior Regulatory Affairs Scientist to serve as a senior regulatory subject matter expert responsible for developing regulatory strategies, leading... 

    VENESCO LLC

    Frederick, MD
    5 days ago
  • General Dynamics Information Technology, Inc. is seeking a Senior Human Subjects Protection Scientist to support the DHA R&D Office of Research and Regulatory Compliance. The role focuses on regulatory-based protocol reviews, adherence to DoD and FDA requirements, and interactions... 
    Work at office

    General Dynamics Information Technology, Inc.

    Frederick, MD
    2 days ago
  • $103.5k - $181.1k

     ...you to achieve your full potential. Unleash your talent and redefine what’s possible.Job Description:Parsons is seeking Research Scientists - Pathogen Genomics and Surveillance to support infectious-disease research at NMRC BDRD. These positions will conduct laboratory... 
    Full time
    Contract work
    Flexible hours
    Afternoon shift

    Parsons

    Frederick, MD
    4 days ago
  • A leading scientific services provider is seeking a Senior Scientist - Histology Technician to support the National Institute of Allergy and Infectious Diseases. This role involves providing histology services, conducting molecular pathology experiments, and operating in... 
    Weekend work

    Cape Fox Corporation

    Frederick, MD
    2 days ago
  • Precision Medicine Group is seeking a qualified scientist to perform flow cytometry and related immune assays, design experiments, analyze data, and document procedures. The role requires a Master3s degree in life sciences and 5 years of laboratory experience, excellent... 

    Precision Medicine Group

    Frederick, MD
    2 days ago
  • NBACC at Fort Detrick, operated by Battelle National Biodefense Institute (BNBI), seeks a Senior Research Associate in Comparative Medicine. The role involves coordinating veterinary support, training staff, and performing advanced animal procedures in a BSL-3/BSL-4 setting...

    Battelle National Biodefense Inst

    Frederick, MD
    5 days ago
  •  ...millions every day. Job Description Seize your opportunity to make a personal impact as a Senior Human Su bjects Protection Scientist supporting the Office of Research and Regulatory Compliance (ORRC), Office of Human Research Oversight (OHRO) at Defense Health... 
    Contract work
    Work at office
    Local area
    Remote work

    General Dynamics Information Technology

    Fort Detrick, MD
    a month ago
  • $115k - $145k

     ...Job Title: Research ScientistJob Description The Research Scientist will lead pre-clinical in vitro and in vivo evaluation of ex vivo and in vivo therapy candidates, supporting the discovery and development of novel cell-based therapies for autoimmune diseases. This... 
    Permanent employment
    Weekend work

    Actalent

    Frederick, MD
    4 days ago
  •  ...Senior Principal Software Engineer Location: Frederick, MD, US, 21703 Job ID: 114808 The Leonardo DRS Airborne and Intelligence Systems business is a global leader and strategic partner committed to delivering world‑class, full life‑cycle defense and intelligence... 
    Principal
    Local area
    Flexible hours

    Leonardo DRS

    Frederick, MD
    4 days ago
  • Translational Pharmacokinetics/ Biopharmaceutics Scientist and Laboratory HeadJob ID: req4313Employee Type: exempt full-timeDivision: Applied & Development Research ProgramFacility: Frederick: Ft DetrickLocation: PO Box B, Frederick, MD 21702 USAThe Frederick National Laboratory... 
    Full time
    Temporary work
    Part time
    For contractors

    Frederick National Laboratory for Cancer Research

    Frederick, MD
    3 days ago
  •  ...AstraZeneca plc in Frederick, MD, is seeking a Principal Engineer – HVAC, Clean Utilities & Process to lead site‑wide technical excellence in GMP HVAC, clean utilities, and manufacturing systems. This role provides technical leadership on capital projects, risk management... 
    Principal

    Jobleads-US

    Frederick, MD
    1 day ago
  • $70.82 per hour

     ...Job Title Sr. Scientist - Histology Technician Job Description The total hourly pay for this exempt position is $70.82 for up to 40 hours per week. This rate represents the company's good faith and reasonable estimate of possible compensation at the time of posting... 
    Hourly pay
    For contractors
    Work at office
    Remote work
    Monday to Friday

    Cape Fox Shared Services

    Frederick, MD
    1 day ago
  • Job ID: 114819 The Leonardo DRS Airborne and Intelligence Systems business is a global leader and strategic partner committed to delivering world-class, full life-cycle defense and intelligence products that protect the security of our nation and our allies. From ...
    Principal
    For subcontractor
    Local area
    Flexible hours

    Leonardo DRS

    Frederick, MD
    3 days ago
  •  ...is currently listed as non-managerial but depending on the qualifications of the applicant could be re-categorized as a Managing Principal. RequirementsLocal to Frederick region or willing to relocate Bachelor and/or Master of Science in Civil Engineering, Geological Engineering... 
    Principal
    Temporary work
    Local area
    Relocation

    Hillis-Carnes

    Frederick, MD
    5 days ago
  • $70.82 per hour

    Sr. Scientist - Histology Lab Manager - (8333) Cape Fox Facilities Services (CFFS) is seeking an experienced Histology Lab Manager to support the NIH. The total hourly pay for this exempt position is $70.82 for up to 40 hours per week. This rate represents the company’... 
    Hourly pay
    For contractors
    Remote work
    Monday to Friday

    Cape Fox Corporation

    Frederick, MD
    4 days ago
  • Who We Are: Goodwin & Associates is a cultural resource management firm expert in meeting local, state, and federal regulatory requirements. Our nationwide practice is supported by full-service offices in New Orleans, Louisiana; Frederick, Maryland; and Lawrence, Kansas...
    Contract work
    Work at office
    Local area

    r c goodwin and associates, Inc.

    Frederick, MD
    5 days ago
  • Job Title - Quality Control Chemist Location - Frederick, MD Duration - 06+ Months Pay Rate - $30/hr on w2 Onsite - Shift flexibility preferred • Wed-Saturday • Time: Day 7:00 AM - 5:30PM EST Responsibilities (include but are not limited to): • ...
    Shift work

    ACL Digital

    Frederick, MD
    5 days ago
  • $90k - $100k

     ...Integrate and visualize multiomics datasets. Assist in systems biology modeling and data interpretation. Work closely with lab scientists to support experimental design. Document pipeline code and support reproducibility standards. Provides laboratory and... 
    Contract work

    Goldbelt

    Frederick, MD
    4 days ago
  • Job Description Our client, a world leader in life sciences and biotechnology, is looking for a "QC Chemist I" based in Frederick, MD. Job Duration: Long Term Contract (Possibility of Conversion to FTE) Pay Rate : $30/hr on W2 Company Benefits: Medical...
    Long term contract

    Dawar Consulting

    Frederick, MD
    4 days ago
  • $45 per day

    Field Archaeologists - R. Christopher Goodwin & Associates, Inc. R. Christopher Goodwin & Associates, Inc. has openings for durational field archaeologists. This position will require travel for which single occupancy lodging and per diem reimbursements of $45 per...
    Hourly pay
    Daily paid

    Goodwin & Associates, Inc.

    Frederick, MD
    2 days ago
  • Job Title: QC Microbiology Technician Duration: 12 months plus extendable contract Location: Frederick, MD 21704 Type of Work: Only on W2 basis Description: ** SHIFT - Sun-Wed 7am to 6pm ** Summary • We are seeking a highly motivated individual to join...
    Contract work
    Shift work

    ACL Digital

    Frederick, MD
    5 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist. Be the first to apply!