Translational PK/PD Scientist — Biologics & PBPK Modeling
Merck
The Translational PK/PD Senior Scientist at Merck is a modeler who designs and executes analyses guiding drug-discovery strategy for biologics, proteins, and peptides. You will collaborate across PDMB and Discovery to build mechanistic models and inform human PK/PD and dose projections. Based in South San Francisco, Boston, or Philadelphia area with hybrid work options, you will lead modeling efforts and develop leadership in translational modeling and drug discovery with supervision as needed. #J-18808-Ljbffr Merck
- Merck & Co., Inc. in the United States seeks a Senior Scientist to lead Translational PK/PD modeling for biologics, proteins, and peptides. You will design and execute analyses guiding drug discovery decisions with supervision, contributing to forward translation across...Suggested
$129k - $203.1k
...and collaborative Senior Scientist for our growing Translational PK/PD organization. The Translational... ...a skilled mathematical modeler and scientist who designs... ...strategy with a focus on biologics, protein therapeutics,... ...vivo data to build PKPD, PBPK, quantitative systems...SuggestedFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$129k - $203.1k
...and collaborative Senior Scientist for our growing Translational PK/PD organization. The Translational... ...a skilled mathematical modeler and scientist who designs... ...strategy with a focus on biologics, protein therapeutics,... ...vivo data to build PKPD, PBPK, quantitative systems...SuggestedFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$124.3k - $230.9k
...seeking a Ph.D. level Senior Scientist who is highly motivated to apply cutting edge translational modeling approaches to support the advancement... ...-based Pharmacokinetic (PBPK) modeling will be a key focus... ...such as Simcyp, GastroPlus, or PK-Sim.You demonstrate strong communication...SuggestedFull timeLocal areaRelocation- Genentech, a member of the Roche group, seeks a PhD-level Senior Scientist to advance translational PBPK modeling for small molecule drug discovery and development. The role focuses on physiologically-based pharmacokinetic analyses and cross-functional collaboration in...SuggestedRelocation
- Genentech seeks a PhD‑level Senior Scientist in DMPK focused on translational PBPK modeling to support small molecule discovery and development. You will strategize, plan and report PBPK analyses, and present findings to cross‑functional teams and senior leadership. The...
- ...talented and motivated Scientist to join our Immunology team... ...pharmacokinetic (PK), biodistribution, and pharmacodynamic (PD) evaluation of BreezeBio... ...bioanalytical platforms in complex biological matrices, nucleic acid–... ...and other preclinical models supporting IND-enabling...Shift work
$147.8k - $274.4k
...leveraging data and novel computational models to drive impact. Seamless data... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...Scientist to join the Perturbation Biology group in the Department of AI for Biology & Translation (AIBT) in Genentech Research...Full timeLocal areaWorldwide$147.8k - $274.4k
...leveraging data and novel computational models to drive impact. Seamless data sharing... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... ...team (DELTA) within the AIBT (AI for Biology & Translation) department in Genentech Research and...Full timeLocal areaWorldwideRelocation package$202.8k - $376.6k
...leveraging data and novel computational models to drive impact. Seamless data sharing... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... ...patients worldwide.The OpportunityThe AI Biology & Translation (AIBT) department within Genentech's Computational...Full timeLocal areaWorldwideRelocation package- Genentech, a Roche company, is seeking an Scientist 3 in Translational Medicine OMNI to advance IBD... ...involves patient-derived materials, complex model systems, and integrative omics... ...experience in immunology or mucosal biology, have 3+ years of hands-on experience...
- ...seeking a Senior Machine Learning Scientist to lead development and... ...research. You will drive foundation models, multimodal AI, and large-language models for translational science, partnering across... ...guide deployment while advancing biology-driven AI applications and...
- ...leveraging data and novel computational models to drive impact. Seamless data sharing... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... ...patients worldwide. The Opportunity AI Biology & Translation (AIBT) develops and applies state-of-the...Local areaWorldwideRelocation package
$90k - $128k
...South San Francisco, California, our scientists are pioneering innovative technology to... ...Associate / Associate Scientist to join our Translational Biology team, supporting our autoimmunity... ...experience in autoimmune disease models is highly desirable Education & Experience...$35 - $47 per hour
Position: Scientist, Translational Pharmacokinetics & Pharmacodynamics (tPKPD) Location: 1 DNA... ...optimization of pharmacokinetic (PK) and pharmacodynamic (PD) properties of therapeutic... ...Bachelor's or Master's degree in Biological Sciences, Pharmaceutical Sciences,...Weekly pay- Genentech seeks a PhD-level Senior Scientist in DMPK to advance PBPK modeling for small molecules. You will strategize, execute, and report simulations, and present findings to cross-functional teams and senior management. The role emphasizes leadership in modeling across...Relocation
$194.1k - $305.6k
...collaborative Senior Principal Scientist to provide scientific... ...with discovery biology, translational sciences, clinical... ...in conjugates, ADME, PK/PD, bioanalysis, and emerging... .... Familiarity with model-informed drug discovery... ...translational PK/PD, PBPK, population PK, exposure...Full timeContract workFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$147.8k - $320.2k
...looking for a highly motivated Senior/Principal Machine Learning Scientist to join their Perturbation Biology group in South San Francisco. This role involves developing advanced machine learning models to enhance drug discovery processes. The ideal candidate should possess...$124.3k - $230.9k
...oversee, interpret and integrate in vitro and in vivo ADME, PK and translate nonclinical data into human PK and dose predictions.... ...development or regulatory interactions.Hands-on experience with PK/PD modeling and/or PBPK modeling using relevant modeling and simulation platforms...Full timeLocal areaRelocation$156k - $166k
...dedicated to unlocking causal human biology and accelerating the delivery... ..., which our TherML platform translates into therapeutics—whether... ....We are seeking a Senior Scientist to join our cardiac disease biology... ...cardiomyocyte (iPSC-CM) models to study the genetic and molecular...Work at officeHome officeFlexible hours- ...projects from discovery through development. The role leads ADME/PK studies, integrates DMPK data into decision making, and... ...industry experience as a DMPK project leader, with hands-on PK/PD or PBPK modeling preferred. Domestic relocation may be offered. #J-18808-Ljbffr...Relocation
$100.4k - $186.4k
...people we love. Genentech's Translational Medicine OMNI (TM OMNI) team supports... ...clinical trial success. Scientists within our department leverage... ...-relevant in vitro human cell models to translate data-driven insights into functional biology. Lead and coordinate exploratory...Full timeLocal areaRelocation package$167.4k - $310.8k
...leveraging data and novel computational models to drive impact. Seamless data... ...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver... ...and complex decision-making.Domain Translation: Translate biological and chemical domain knowledge into machine...Full timeLocal areaWorldwideRelocation package$103.4k - $192k
...gRED) is seeking a motivated scientist to help develop novel cell... ...with deep expertise in T cell biology and a strong foundation in... ...effectively with research, translational, computational, process development... ....Familiarity with in vivo models of liquid and solid...Full timeLocal area$143.2k - $266k
...makes us Genentech! The Translational Genomics and Proteomics Center... ...our understanding of human biology and disease. A position is... ...and innovative Principal Scientist to lead research at the intersection... ...vitro and in vivo disease models to identify novel biological...Full timeLocal areaRelocation package$100.4k - $186.4k
...PositionThe PositionGenentech's Translational Medicine OMNI (TM OMNI)... ...development.The OpportunityAs a Scientist 3 in Translational Medicine... ...will apply human-relevant models and high-dimensional omics data... ...) to investigate pathway biology and therapeutic mechanisms of...Full timeLocal areaRelocation package$141.1k - $262.1k
...leveraging data and novel computational models to drive impact. Seamless data... ...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver... ...complex reasoning challenges.Domain Translation: Translate biological and chemical domain knowledge into...Full timeWork experience placementLocal areaWorldwideRelocation package$140k - $170k
...development of generative AI models to design protein and antibody... ...foundation models for biology and disease to enable better... ...is seeking a lab-based Senior Scientist in Inflammation and Immunology... ...suppression, migration) ~ Translate experimental data into actionable...Full timeFlexible hours$201.3k - $373.8k
...data and novel computational models to drive impact. Seamless data... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...our computational methods and translate them into measurable impact on... ...ExpertisePhD in Computational Biology, Biophysics, Immunology, Chemistry...Full timeLocal areaWorldwideShift work- ...antibody conjugation scientist who will build this capability... ...advanced in vivo and translational studies. This is a... ...for pharmacology, PK/PD, and other advanced studies... ...(site selection, modeling), and external CROs/CDMOs... ..., chemical biology, or a related field preferred...
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