Senior Regulatory Affairs Director - Oncology (Gaithersburg)

Senior Regulatory Affairs Director - OncologyAre you a strategically focused Regulatory professional and would like to play an integral part in bringing life changing Oncology medicines to patients? If you are please read on!About AstraZeneca At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.Oncology Regulatory Science and StrategyWithin Oncology Regulatory Science and Strategy (ORSS) we bring hope and solutions to patients with unmet needs across the globe. As Regulatory professionals working on Oncology products, we work in areas of unmet need and take innovative regulatory approaches to bring life-changing treatments to patients. We work across our pipeline and the business to get medicines to patients as efficiently and effectively as possible.The Senior Regulatory Affairs Director (SRAD) serves as the Franchise Global Regulatory Lead (GRL) developing and implementing the global strategy on complex oncology programs with multiple indications. In addition, the SRAD has the ability to function in dual capacity by serving as the regional lead based on location. The SRAD establishes external relationships with key stakeholders, leveraging these to maintain competitive advantage. You will be viewed as a senior leader within the Regulatory community.What you’ll doLead a Global Regulatory Strategy Team (GRST) of GRLs within the franchise, contributing members from the regions, emerging markets, RA CMC, Labelling and members of the submission and execution team.Ensure that the strategy is crafted to deliver approval with competitive labelling in keeping with the properties of the product(s) and the needs identified by the business, markets and patients.Lead the assessment of emerging data against aspirations and update Leadership on project risks/mitigation activities.Represent Regulatory Affairs on Global Product Teams (GPTs) providing strategic advice and accountable for all regulatory activities.Own the delivery of all milestones on your team including assessment of the probability of regulatory success based on a detailed assessment of risks and mitigations.Demonstrate strategic leadership skills thereby contributing to effective product development.Promote novel regulatory initiatives internally and engage externally on the corresponding topics. Lead the development of novel tools and technology.Partner and influence developing views/guidance on a global scale.Essential Skills/Experience:Bachelors degree in a scientific discipline with 10+ years relevant experience/knowledge.Deep understanding of global regulatory science and integration with program strategy.7+ years experience of overall drug/biologic development processes and strategies for high profile, complex or novel development programs.Broad background of experience working in pharmaceutical business and prior experience in several areas within regulatory affairs.Proven experience leading regulatory, cross-functional teams, and stakeholder management.Successful leadership of at least one global regulatory marketing approval as GRL across major regions (US and EU) including leading response team and labeling negotiations.Ability to think strategically and critically and evaluate risks to regulatory activities.Previous experience in leading major Health Authority interactions.Excellent oral, written, and presentation skills.Strong organisational skills.Ability to work in a fast-paced environment in a hands-on fashion.Flexible and proactive, with the ability to manage multiple projects and successfully adapt to changing business needs and priorities.Desirable Skills/Experience:Experience in the development or application of radio-conjugates would be highly advantageous.Experience with FDA advisory committee and CHMP oral explanation.Experience working on due diligence activities and in a business alliance environment.Experience in leading and growing people through coaching or mentorship.Contribution to non-project business initiatives (e.g. at a portfolio or cross functional level).Experience in Oncology (small molecules and biologics) is preferred.​Why AstraZeneca?At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.So, what’s next? Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!Competitive salary and benefits package on offer:Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. The annual base salary for this position ranges from $211,581.60 - 317,372.40. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.  Date Posted17-Jul-2026Closing Date24-Jul-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.SummaryLocation: US - Gaithersburg - MDType: Full time