Medical Doctor

Job Title: Physician

Clinical Research Physician (No Research Experience Required)

MD or DO – Principal Investigator Role

Location: Knoxville, TN

Pay: $300,000 (DOE)

Benefits: Full Benefits Package, 401(k), PTO

Schedule: Full-time, Weekdays Only | No Nights | No Weekends | No Call

About the Opportunity

Clinical research changes the course of lives — sometimes in small, unseen ways, and sometimes in ways that transform the future of medicine. A patient with a rare disease gaining years they never thought they’d have. A new therapy turning a once-debilitating condition into something manageable. A breakthrough that lets a parent return to work, care for their family, and live fully again.

Every medical advancement starts somewhere — and it starts with physicians willing to lead the way. That physician could be you.

Join a leading national clinical research organization with over 30 U.S. sites as a Principal Investigator . You do not need prior research experience — if you’re an MD or DO in any specialty , we’ll provide complete training and the tools to succeed.

In this role, you’ll directly impact lives by overseeing and participating in clinical trials for innovative new treatments and federally funded studies. You’ll keep practicing medicine while enjoying predictable hours, zero call, and no overnight shifts — all in a supportive, well-structured environment that allows you to focus on what matters most: advancing patient care.

Our culture is built on experience, integrity, and collaboration . You’ll join a team of dedicated professionals and strong leadership who value your contributions, respect your expertise, and work together toward a shared mission. Many of our physicians and staff have been with us for years — a testament to the trust, camaraderie, and fulfillment they find here.

Why This Role Stands Out

• No research experience required – full training provided
• Excellent work-life balance – no nights, no weekends, no call
• Competitive compensation – $250k+ DOE plus bonus
• Wide variety of studies – 30+ therapeutic areas including vaccines, chronic conditions, CNS, and more
• Strong infrastructure – dedicated coordinators, regulatory staff, and admin support handle logistics so you can focus on patients
• Meaningful impact – help bring new treatments to patients faster

Who This Is Ideal For

• ER doctors or hospitalists seeking steady hours and reduced stress
• Primary care physicians or internists looking for a career change
• Physicians approaching retirement who still want to make an impact
• New grads interested in a unique clinical path
• Tech-comfortable doctors (experience with EHRs or digital systems)

Qualifications

• MD or DO with active medical license (any specialty)
• Strong patient care skills and sound clinical judgment
• Comfortable using medical and research software systems
• Prior PI experience welcome, but not required

Apply today for a confidential discussion about transitioning into clinical research while keeping work-life balance a top priority.

Keywords for Job Boards: Clinical Research Physician | No Research Experience Needed | Principal Investigator | MD or DO Jobs | Knoxville TN Physician Job | Doctor Career Change | Vaccine Trials | No Call Physician Role | Weekday Only Doctor Job | Clinical Trials | Alternative to Hospital Medicine | Semi-Retired Physician Opportunity | Work-Life Balance for Doctors | Research Training Provided | Clinical Research Organization | FDA-Regulated Trials