Senior Scientist, PK/ADME Biotherapeutics
Amgen SA
Amgen in South San Francisco seeks a Senior Scientist to advance PKDM programs by designing and executing biological and biophysical experiments to characterize ADME of large molecules in discovery and early development. The role emphasizes lab-based assay development, data interpretation, collaboration with project teams, and potential leadership in department strategy for PKDM project teams. #J-18808-Ljbffr Amgen SA
- ...motivated DMPK leader to drive strategy and oversee non-clinical ADME/PK studies across discovery and development. You will serve on... ...project leadership, and strong communication skills to inform senior stakeholders and regulatory discussions. #J-18808-Ljbffr RocheSenior
- Amgen in South San Francisco, CA, is seeking a Senior Scientist - PKDM-BA to design and execute biological and biophysical experiments to understand ADME properties of large molecule therapeutics in support of drug discovery and early development. This lab-based role emphasizes...Senior
- Amgen in the United States seeks a Senior Scientist - PKDM-BA to design and execute biological and biophysical experiments to understand ADME properties of large molecule therapeutics, supporting drug discovery and early development programs. The role is lab-based with...Senior
- Kardigan is seeking a Scientist, Drug Metabolism and Pharmacokinetics (DMPK) to join the Discovery Research team in South San Francisco,... ...site four days a week. The role focuses on generate high-quality ADME/PK data across early discovery to development, with emphasis on...Suggested
- Amgen seeks a scientist in Pharmacokinetics & Drug Metabolism - Bioanalytical Sciences (PKDM-BA) to develop and apply LC-MS-based bioanalytical assays for endogenous proteins, proteoforms, and target-drug complexes. The role spans discovery to regulatory support, requiring...Senior
- ...Quantitative, Translational ADME Sciences (QTAS) department at... ...is seeking a highly motivated scientist to join the Novel Biologic Entities... ...to support in vivo PK, TK, and PK/PD studies as well... ...characterization of complex biotherapeutic modalities. The candidate will...SeniorTemporary work
- Merck & Co., Inc. in South San Francisco seeks a laboratory-based scientist to generate in vitro and in vivo ADME and PK data to support biologics programs in the DMPK group. You will apply protein biochemistry and biophysics to understand how molecular properties influence...
- Switch Therapeutics in South San Francisco is seeking a Senior/Principal Scientist to lead bioanalytical characterization of oligonucleotide therapeutics, integrating LC-MS/MS and LC-HRMS with PK/PD interpretation. This hands-on role guides method strategy and mentors junior...SeniorFull time
- AbbVie is seeking a highly motivated scientist in QTAS to develop and implement LC/MS-based bioanalysis for novel biologics. You will lead... ...method development, and data interpretation to support in vivo PK, TK, and PK/PD studies. The candidate should have PhD/MS/BS with...Senior
- Genentech is seeking a Senior Scientist in translational PKPD to advance preclinical ADME/PKPD studies and support INDs/BLAs under supervision. The role involves independent design, data interpretation, and collaboration with Clinical Pharmacology, Biochemical Sciences...SeniorRelocation package
- Genentech is seeking a Senior Scientist in the translational Pharmacokinetics and Pharmacodynamics (tPKPD) team within gRED to advance PKPD science... ...pipeline. You will design and execute in vitro and in vivo ADME/PKPD studies, generate regulatory-ready documents, and...SeniorRelocation package
$174.9k - $185.2k
We are growing the team with a hands-on antibody conjugation scientist who will build this capability from the ground up by developing and... ...conjugation runs (mg to multi-mg) to produce material for pharmacology, PK/PD, and other advanced studies on program timelines. Purify...Senior- ...interactions, and etc., across discovery and development programs. This scientist will be expected to identify the appropriate analytical approach... ...project teams to interpret bioanalytical data in the context of PK/PD, translational biomarkers, target biology, and mechanisms of...Senior
$143.82k - $194.58k
...transform the lives of patients while transforming your career. Senior Scientist - PKDM-BA What you will do The responsibilities of the... ...execute biological and/or biophysical experiments to understand the ADME properties of large molecule therapeutics (and non-traditional...SeniorFlexible hours$120.7k - $224.1k
...have more time with the people we love. This opening is for a Senior Scientist position in the translational Pharmacokinetics and... ...Design, conduct, analyze and interpret all in vitro and in vivo ADME and PKPD studies that are necessary to understand the pharmacology...SeniorLocal areaRelocation package- NewLimit seeks a Scientist/Senior Scientist of In Vivo Pharmacology to lead in vivo studies evaluating epigenetic reprogramming therapeutics. You will design, execute, and interpret PK/PD, efficacy, and dose-response studies across disease models, collaborating with Epigenetic...Senior
$130k - $180k
...unprecedented scale. Description NewLimit is seeking a talented Scientist / Senior Scientist of In Vivo Pharmacology to join our Translational... ...entire portfolio.As a subject matter expert in nonclinical and PK/PD study design, you will lead in vivo pharmacology strategies...Senior- TCG Labs-Soleil seeks a Senior Scientist, Bioanalytical Sciences to lead PK/ADA and biomarker assays across discovery to clinical development. The role demands strategic vision, hands-on expertise, and strong collaboration with cross-functional teams in a dynamic biotech...Senior
$134.8k - $240.8k
Senior Scientist, Bioanalytical Sciences Department: Bioanalytical Sciences / Nonclinical Development Position Summary: TCG Labs-Soleil is... ...teams, formulates the bioanalytical strategy for pharmacokinetic (PK), anti-drug antibody (ADA), and biomarker assays across a...SeniorTemporary workFlexible hours$143.07k - $162k
...abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok. Job Description Senior Scientist 1, Bioassay Development, CMC Biologics, Analytical Research & Development, AbbVie Biotherapeutics Inc., South San Francisco, CA: Onsite (onsite 5 days per week). Key...SeniorTemporary workWork experience placement- ...the world’s most complex and serious diseases. Within the Biotherapeutics and Genetic Medicine (BGM) organization, the newly established... .... AbbVie is seeking a highly talented and motivated Senior Scientist I to join our siRNA therapeutics team within BGM at the South...SeniorFull timeTemporary workLocal area
$167.88k - $178.5k
...on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok . Job Description Senior Scientist II – CMC Developmental Sciences, AbbVie Biotherapeutics Inc., South San Francisco, CA (100% onsite). Key Responsibilities • Perform on various aspects...SeniorFull timeTemporary workWork experience placement$148k - $183k
...medicinal chemistry concepts: structure-based design, SAR-driven design, multi-parameter optimization, physicochemical properties, and ADME/pharmacology principles. - Desire to continually learn and stay current in drug discovery and structure-based design. Total Rewards...Senior$141.31k - $171.24k
...it. Position Summary We are seeking an experienced and highly motivated Senior Scientist to lead and expand high-throughput biologics production capabilities within Discovery Biotherapeutics. This hands-on, laboratory-facing leadership role will oversee the design,...SeniorHourly payFull timeSummer workLive inLocal areaRemote workFlexible hours$148k - $183k
...parameter optimization, physicochemical properties of drugs, and ADME and pharmacological principles applied to drug discovery... ...programs. The expected salary range for the role of Senior Research Scientist, Medicinal Chemistry is $148,000 - $183,000. The final salary...SeniorContract workTemporary workWork at officeLocal area- ...mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs... ...teams We are seeking a Senior Associate Scientist, Bioanalytical Sciences... ...including independent, hands-on development of PK, anti-drug antibody (ADA) and/or biomarker...SeniorLocal areaFlexible hours
$170k - $200k
...Position Summary: We are seeking a talented and highly motivated Senior Clinical Scientist to join our Clinical Development team. This position offers... ..., indication(s), compound(s) under study (including MOA, PK/PD, biomarker & safety profile) Proficient critical...SeniorWork at officeShift work2 days per week3 days per week- Enigma Search is seeking a Scientist I, Bioanalytical to oversee the development, validation, and execution of bioanalytical assays for PK/PD across preclinical and clinical programs. The role involves managing CROs, ensuring data integrity, and contributing to regulatory...
- NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development to lead PD biomarker assays that characterize the biological activity of our mRNA-LNP medicines in preclinical and IND-enabling studies...Senior
- Freenome seeks a Senior Development Scientist I to advance our multiomic, clinical-grade DNA/NGS assays in a production-ready setting. You will lead verification/validation studies, design robust experiments, analyze data, and present findings to diverse teams across a...Senior
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