Lead Incident Response Analyst

Job-ID: 12676Category: Information ServicesLocation: Marlborough, MA, United StatesSchedule: Full timePosted: 2026-11-05As a Lead Incident Response Analyst, you will be a senior member of Hologic’s enterprise Threat Detection and Response team. The team provides 24x7x365 monitoring of security-related information sources to detect and manage cyber, privacy, and data-protection incidents affecting Hologic data and infrastructure. The team regularly hunts across the Hologic network for signs of compromise, malware, or unauthorized access; develops and maintains incident response plans, playbooks, and procedures; and collects and analyzes incident response data.Your Daily Impact at Hologic: Lead security incidents from detection through containment, eradication, and recovery, serving as incident commander and coordinating response across IT, Legal, Privacy, Communications, and business stakeholders.Stay current on relevant vulnerabilities, threat actors, indicators of compromise (IOCs), tactics, techniques, and procedures (TTPs), and emerging trends, and turn that intelligence into actionable insights.Partner with Crisis Management to activate and execute crisis procedures when necessary.Use threat intelligence to proactively hunt across the Hologic enterprise for anomalous or malicious activity.Work with Security Engineering to baseline user behavior and events, and to build new detections and response workflows.Mentor and guide analysts, review investigations and escalations, and set quality standards for the team’s detections, playbooks, and case documentation.Lead post-incident reviews, documenting root cause and lessons learned, and drive remediation actions to closure.Recommend and build countermeasures based on threat analysis and intelligence.Develop, implement, and maintain security incident playbooks and runbooks, including building SOAR-driven automation workflows.Routinely test and improve operational effectiveness through purple team exercises.Prepare and present findings and recommendations through briefings, reports, and dashboards to managers, team leads, and senior leadership.This position supports a 24x7x365 operation and may require shift and/or on-call work, including weekends.You Bring to Hologic:Bachelor’s degree in a related field, or equivalent experience5+ years of information security experience, focused on incident response or threat detectionDemonstrated experience leading incidents and mentoring or guiding other analystsStrong knowledge of incident response principles and processesExperience with EDR (Endpoint Detection & Response) analysis and rule creation, and with dissecting attacker tactics and techniquesExpert-level experience with Splunk, including reporting and data correlationExcellent analytical and problem-solving skillsA learning mindset and enthusiasm for new technologies and security disciplinesBonus points for: In-depth knowledge of Splunk’s architecture and underpinningsPrevious experience in cloud-native or technology environmentsNetwork or Linux knowledgeProgramming or scripting experienceExperience developing SOAR workflows, including agentic and non-agentic automation (training provided for candidates new to SOAR)Security certifications such as GCTI, GCIH, GCIA, or GPENThe annualized base salary range for this role is $114,000 - 178,300 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, geography, education, business needs, and market demand.Why Hologic?We are committed to making Hologic the company where top talent comes to grow. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career.If you have the right skills and experience, apply today!#LI-AV1Agency and Third Party Recruiter Notice:Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.Hologic, Inc. is proud to be an Equal Opportunity Employer inclusive of disability and veterans