Research - Associate Scientist II

Research Associate Scientist II

The experienced Research Associate Scientist II, with a background in in vitro screening, will be part of our dynamic, fast-paced and interdisciplinary lead development team. Our mission is to advance Client RNAi therapeutic programs from target discovery through lead candidate selection. The Associate Scientist II will be technically skilled in molecular and/or cell biology, and bring a rigorous, analytical approach to research.

This position is onsite and will be primarily located in Cambridge, MA.

Key Responsibilities

• Perform cell culture (iPSCs, primary cells, immortalized cell lines) to support the research needs of the group and high-throughput screening of siRNAs using qPCR and a variety of cell-based assays
• Execute day to day operations for RNASeq sample preparation, including: library preparation, QC and sequencing. Maintain sample tracking & records.
• Conduct assays that support in vivo studies (e.g. qPCR, ELISA) for the quantitative analysis of biomarkers or siRNA activity
• Support lab maintenance including equipment operation & maintenance, reagent inventory and reagent preparation
• Troubleshoot technical problems and participate in the continuing development and optimization of existing and new protocols.
• Utilize instrumentation and robotics to aid in high throughput (384-well) screening.
• Adapts well to the changing platform needs, in workflow, projects and other tasks as required by the platform.

Qualifications

• A BS in a biological science with at least 2 years of hands-on laboratory experience in cell or molecular biology are required
• Experience in cell culture and purification/quantification of nucleic acids/protein, including qPCR
• Experience with NGS workflow is desired
• Experienced with laboratory automation including liquid handling systems such as Perkin Elmer JANUS, Beckman i7 or other systems.
• The candidate should be intensely detail oriented, highly motivated, capable of managing multiple projects simultaneously, desire to drive innovation, and willingness to learn
• We particularly seek someone who is detail oriented and who will flourish in a goal-driven team environment under tight deadlines.
• Excellent interpersonal skills with the ability to work well with others in a dynamic and highly collaborative environment.

EEO Employer LanceSoft is a certified Minority Business Enterprise (MBE) and an equal opportunity employer. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship. LanceSoft makes hiring decisions based solely on qualifications, merit, and business needs at the time.