Vice President, Head of Data Science & Biostatistics

Role Description

We are seeking a Vice President, Head of Data Science & Biostatistics to provide strategic and operational leadership for data sciences across late-stage clinical development for multiple Phase 3 gene trials as well as early stage clinical studies focused on neuromuscular and cardiac diseases. This role will partner cross-functionally to ensure the integrity, rigor, and translational value of clinical data, enabling decisive regulatory, clinical, and commercial outcomes. This leader will oversee a team of biostatisticians and serve as the accountable executive for statistical strategy, data science innovation, and biostatistics integration across clinical programs. The VP will play a critical role in advancing registrational studies, regulatory filings, and lifecycle management while building scalable capabilities to support commercialization and post-marketing evidence generation.

Reporting to the Chief Medical Officer, the role will be flexible based on location and alignment with the CMO.

Key Position Responsibilities

• Define and execute the company’s data science, biostatistics, and biostatistics strategy aligned to Phase 3 execution and regulatory success.
• Serve as a core member of the Clinical Leadership Team and partner with the CMO on clinical strategy.
• Lead statistical design and execution of Phase 3 trials, including SAPs, protocols, and interim analyses.
• Ensure compliance with GCP, ICH guidelines, and regulatory expectations.
• Support regulatory submissions (BLA/MAA) and health authority interactions.
• Integrate biost and multi-omics data into clinical development.
• Advance modern data science approaches, including modeling and AI/ML where appropriate.
• Lead and develop a team of 4 biostatisticians.
• Lead and develop a team of 3 database managers.
• Manage CROs and external partners.
• Partner cross-functionally across Clinical, Regulatory, Medical Affairs, and Commercial.

Qualifications

• Master’s degree or higher in Biostatistics, Statistics, or related field.
• 15+ years in biotech/pharma with late-stage clinical experience.
• Proven success supporting regulatory submissions and FDA/EMA interactions.
• Experience in gene therapy, rare disease, or neuromuscular/cardiac indications preferred.
• Expertise in clinical trial design, statistical methods, and regulatory standards.
• Strong leadership and communication skills.

Key Position Attributes

• Strategic Judgment with Clinical Impact: Translates complex data into clear, decision-ready insights and anticipates risks in trial design, endpoints, and data interpretation. Balances scientific rigor with speed in a late-stage environment.
• Executive Communication & Influence: Distills statistical complexity into concise messaging for the CMO, ELT, and Board; effectively represents the company with regulators and external stakeholders.
• Ownership & Accountability: Operates as the single point of accountability for statistical strategy and data integrity; drives critical milestones with urgency and accountability.
• Hands-On Leadership in a Lean Environment: Functions as a player-coach, willing to engage deeply in technical work while leading a small, high-impact team and prioritizing effectively.
• Talent Development & Team Leadership: Builds, mentors, and retains a high-performing team of biostatisticians; elevates technical rigor, communication, and execution standards.
• Cross-Functional Integration: Seamlessly integrates clinical, biostatistics, and translational data; aligns stakeholders across Clinical, Regulatory, and Technical functions.

Compensation

The base compensation range for this role is: $288,275 - $377,128. Base salary offered is determined through an internal analysis utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity. Regular employees are eligible to receive both short-term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward individual performance and align incentives to Solid’s long term company performance.

Benefits

• Competitive Health and Dental programs with flexible plan offerings, including FSA and HSA programs.
• 401(k) program participation with competitive company matched contributions.
• Eligibility to participate in Solid’s Employee Stock Purchase Plan.
• Mobile phone subsidy for eligible employees.
• Tuition Reimbursement.
• Vision Coverage.
• Life Insurance.
• Voluntary Pet Insurance.
• Employee Discount Program on Travel, Entertainment, and Services.
• Daily Subsidized Lunch Delivery (onsite @ Hood Park).
• Free Onsite Full-Service Gym (onsite @ Hood Park).
• Employee Parking (onsite @ Hood Park).