Senior IS Technical Project Manager - Project Management Office
$130.93k - $140.23kDana–Farber Cancer Institute
Overview
POSITION SUMMARY
The Technical Senior Project Manager III leads high-profile, matrixed projects aligned with the Institute’s strategic plan and process improvement priorities, often spanning multiple divisions. This role involves planning and managing several projects simultaneously, ensuring timely delivery within scope and budget. Engaging with diverse stakeholders, including senior leadership, the manager drives project success and fosters cross-departmental collaboration, focusing on strategic outcomes and innovation. With proven technical expertise, they partner with engineering and development teams to mitigate risks and lead technology decisions, while also driving system architecture discussions, IT policy development, code reviews, and technical feasibility assessments. Incumbent will report to the Manager of the Dana-Farber Cancer Institute (DFCI) Information Services (IS) department Project Management Office (PMO), managing large projects identified by DFCI IS leadership while utilizing the PMO’s established project management methodology. The focus of this position is: 1) manage large-scale initiatives, 2) represent the PMO with the use of the PMO’s proven methodologies and tools, 3) support DFCI staff in project management best practices through coaching, mentoring, and training, 4) communicate the PMO’s mission and purpose throughout the IS and user community, and 5) drive the deployment, support, and continuous improvement of standard project management tools, including templates and applications, throughout DFCI. The incumbent will:•work closely with a multi-disciplinary team including IT technical staff, business analysts, institute leaders, and external vendors/teams throughout each project
•establish and maintain respectful relationships with project sponsors and stakeholders
•become familiar with institute processes, strategic goals, and systems
•collaborate with the business in needs definition, business assessment, requirements gathering, vendor selection, resource allocation, project prioritization, risk analysis and mitigation, implementation, testing, training, and project closeout
•lead and assist teams in project design
•aid in the periodic review and auditing throughout a project’s lifecycle
•guide projects in process content, application of tools, and knowledge management
•proactively identify, analyze, mitigate, and manage risks
•regularly and proactively communicate with project stakeholders regarding schedule, status, issues, risks, scope changes, and milestone achievements The estimated duration of this position is 24-36 months.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
PRIMARY DUTIES AND RESPONSIBILITIES
- Scope and Complexity: Oversee highly complex projects with budgets exceeding $1M, critical to strategic objectives, involving multiple departments and external partners.
- Strategic Leadership and Planning: Lead strategic decision-making with full accountability for project outcomes and resource management, collaborating with senior leadership to translate initiatives into detailed project plans that align with institutional priorities and ensure measurable success.
- Analysis: Translate business processes into technical solutions, expertly guiding analysts in requirement gathering and performing analysis as needed.
- Stakeholder Interaction and Communication: Engage with executive leadership and diverse stakeholders to drive project success and foster organizational collaboration.
- Project Oversight: Lead planning, execution, and evaluation of large-scale projects, ensuring timely delivery within scope and budget, while proactively managing portfolio impact.
- Quality and Risk Management: Drive innovation and continuous improvement by aligning quality objectives with organizational goals, while proactively identifying, analyzing, and managing risks to minimize issues and enhance project success.
- Vendor Management: Lead large vendor selections and implementations involving multiple vendors.
- Mentorship and Development: Mentor project teams, promoting professional growth and a culture of excellence.
KNOWLEDGE SKILLS AND RESPONSIBILITIES
- Extensive experience in project management, with a proven track record of delivering complex projects successfully.
- Strong leadership and interpersonal skills, with the ability to influence and engage stakeholders at all levels.
- Exceptional problem-solving and decision-making abilities, with a focus on strategic thinking and innovation.
- Expertise in project management software and templates, with a strong application of project management methodologies and scheduling solutions such as MS Project
- Exceptional communication skills, both written and verbal, with the ability to convey complex information clearly and concisely.
- Ability to manage multiple priorities and adapt to changing circumstances in a fast-paced environment.
- Strong analytical skills, with the ability to interpret data and make informed decisions.
- High success in applying complex IT concepts in application development and support, networking, system integration, and information security.
- Expertise with Software Development Life Cycle (SDLC)
- Champion of formal project management methodologies, including waterfall, spiral, agile, lean, DMAIC, etc.
- Accomplished written and verbal communications skills with staff through leadership of varying levels of technical aptitude, translating business needs into technical solutions and driving decisions
Education Required
Bachelor's Degree
Area of Study Required
Computer Science, Information Technology, Engineering, or a related technical field.
Experience Required
Ten (10) years of relevant experience with progressively increasing responsibility of which at least six (6) years must be in project management OR comparable roles.
License/Certification/Registration Required
Project Management Professional (PMP) or Program Management Professional (PGMP) certification required, with expectation to maintain credential.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
.Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$130,930.00 - $140,230.00$113.83k - $124.89k
...Overview POSITION SUMMARY: The Technical Project Manager III leads and executes complex... ...(DFCI) Project Management Office (PMO) in Information Services (IS), managing medium to large complex... ...and Communication: Engage with senior leadership and external partners...PMOFull time$94k - $176k
...Senior IT Project Manager Information Technology All Practice Areas Boston, Charlotte... ...experience and superior technical knowledge, and is both... ...educates others outside of IS on department’s standard Project... ...knowledge in MS Project, MS Office and Visio. Education Required...SeniorPMOFull timeTemporary workLocal areaRelocationFlexible hours- ...Health Insurance Exchange team as a Senior IT Project Manager. The Senior IT Project Manager is a key... ...of the Enterprise Project Management Office (EPMO) team, supporting key... ...effective communication between non-technical and technical teams. Monitor results...SeniorPMOWork at office
- Talentify is seeking a Senior IT Project Manager to join the Health Insurance Exchange team within the Enterprise PMO. You will oversee large IT projects, define roles, coordinate activities, and ensure delivery on time and budget while aligning with agency standards. You...SeniorPMO
$130.93k - $140.23k
...Overview The Senior Technical Project Manager leads high-profile, matrixed projects supporting Blood Donor Services, Apheresis, and Blood Bank operations, often spanning multiple departments and external partners. The role’s initial primary focus will be leading...SeniorFull time- The TeamWe are seeking a Project Manager to join American Tower’s Information Security Team. The... ...initiatives while providing Program Management Office (PMO) support. You will be responsible... ...Management, and/or related field is required.Project Management Professional...SeniorPMOWork experience placementWork at officeLocal area
$128k - $155k
...as we help shape a brighter way forward. Senior Director, Performance - JLL (Life Sciences... ...role. It is a function builder, not a people manager, and it is accountable for whether... ...performance role in Life Sciences. The account is the hiring manager; this role has a documented...SeniorPMOFull timeContract workLocal areaRemote work$120k - $202.5k
...Looking For We are seeking a Senior Security Testing... ...coordination, and operational management of State Street’s... ...is ideal for a strong technical program leader who can... ...succeed in this roleStrong project management and... ...driven security programs is preferredFinancial services...SeniorFull timeTemporary workFlexible hours$133k - $155.7k
...Job Profile Summary The Senior Consulting Manager supports large-scale transformations at Dana-Farber... ...in-depth analysis, and maintains project structure to drive large-scale organizational... ...risks • Manages project management office functions including program management...SeniorPMOWork experience placement$114.11k - $148.35k
...DEPARTMENT: Office of the Chief Information Officer (OCIO) SUMMARY The Senior Salesforce Administrator works on the Enterprise... ...CRM Team leading the management of digital customer relationship... ...COBIT, SOX, GDPR Support Project Activity Define and contribute...SeniorPMOWork at office- The Executive Office of Health and Human Services... ...to fill the Senior Business Analyst/Data... ...Enterprise Data Management & Engineering (... ...The ideal candidate is an expert in Data... ...both business and technical stakeholders to ensure... ...and technical projects of a wide range of...SeniorPMOWork at office
$172k - $220k
...ServicesCompensation:Salaried ExemptLocation: Position can be performed from any U.S. company office, with opportunity for office and remote work.Position DescriptionThe IS Lead Technical Project Manager HQ leads complex, cross-functional technology projects and coordinated programs...Work at officeRemote work- ...focused environment. If you are a technically proficient, nimble, user-... ...as building strong people and project management skills. Learn more here: .Job DescriptionThe Senior Project Manager leads project... ...Onstie work is performed in an office settingVisa Sponsorship Information...SeniorContract workWork experience placementWork at office
- ...effective and sustainable imaging data management. From product development to implementation... ...and business strategies. The Senior Project Manager must plan, execute, deliver, implement... ...Project Management and other Microsoft Office products Proficient in tools and...SeniorPMOLive inRemote workWork from homeHome officeShift workAfternoon shift
$131k - $218.3k
...Operations Integration and Delivery, Managed Services Manager on the... ...relationshipsAbility to lead projects or workstreamsAbility to... ...management, project management office operations, modernization, process... ...entry-level employees to senior leaders, we believe there’s always...PMOContract workFor contractorsFor subcontractorLocal area- ...ideal candidate will have a strong background in enterprise IT project management and organizational change management, with experience... ...implementation support. Experience working with business teams, technical teams, and executive-level stakeholders. Demonstrated...Senior
- ...DescriptionThe RoleWe're looking for a Senior Program Manager to join our PMO team and lead complex,... ...environment. This person will drive projects delivery across engineering, product,... ...Bring to the Team7–10 years of program/technical program management experience, majority...SeniorPMOFull timeFlexible hours
- ...MasterThe Scrum Master will be responsible for supporting complex projects/products and programs using pre-existing knowledge, skills,... ...phases of the project/product lifecycle using project/product management practices. This position is responsible for concurrently...Senior
- Boston, MA100% RemoteFull Time$123k - $144kWe are looking for an IT Project Manager II for a full-time, remote opportunity with a leading insurance and risk management organization. Candidates local to the Boston, MA area are preferred. This person will lead technology...SeniorFull timeLocal areaRemote work
$155.6k - $306.8k
...for this role ends on 10/31/2026. Work You'll Do As a Senior Manager on the team, you will be responsible for: Owning end-to-end project delivery, including the integrated project plan and schedule across technical and functional workstreamsLeading full implementation...SeniorPMOFor subcontractorLocal area$86.8k - $165.2k
...after day 1Raytheon Company, Managed by Collins AerospaceCollins Aerospace... ...portfolio and deep technical expertise, we help customers... ...Collins Aerospace is seeking an Senior Agile Scrum Master to support... ...process in-person at one of our office locations, regardless of...SeniorTemporary workWork experience placementWork at officeRemote workRelocation packageFlexible hours$130k
...to unlock potential in every person or project and redefine the boundaries of ambition.... ...people we want to join us on our journey.Managing, and may directing, the implementation and... ...: 43616Date posted : 2026-06-25Profession: Technical ServicesEmployment type: Full-timeSeniorPMOFull timePart timeFlexible hours$117k - $170k
...Senior Delivery ManagerThe Senior Delivery Manager is responsible for managing the full lifecycle of technical product and program delivery — from business case creation and approval,... ...based work and traditional technology project management. This person will have strong...SeniorFull timeTemporary workFor contractorsWork from homeWork visaFlexible hours3 days per week$165k
Keolis Commuter Services in Somerville, MA is seeking a PMO Director with 12+ years in project management for large capital transit programs. You will lead multiple projects from planning through execution, ensuring schedule, cost, risk, and safety standards are met. A...SeniorPMOContract work$97.9k - $133.5k
...caring community The Senior Scrum Master... ...ensuring the team focuses on technical needs, including improvements... ...leveraging change management frameworks such as... ..., technically complex projects. ~ Thorough understanding... ...Home or Hybrid Home/Office employees’ ability to...SeniorFull timeTemporary workApprenticeshipWork at officeRemote workWork from homeHome office$110k
...Defense, Automotive & Assembly, Capital Projects & Infrastructure, Chemicals, Consumer Packaged... ...up and run best-in-class transformation offices and performance infrastructures that... ...analytical tools to support program management, impact capture, and financial modeling....SeniorPMOApprenticeshipEasy workShift work$124k - $280k
...SummaryThe OpportunityAs a Cloud Infrastructure and Operations Senior Manager you will lead client-facing cloud infrastructure and... ...infrastructure operations background, and ability to translate technical needs into practical actions for clients.In this role, you will...SeniorFull timeH1b$80k - $140k
...Engineering & Operations (TPEO) is seeking a highly motivated Technical Project Manager (AVP) to lead the delivery of complex technology programs... ...some or all of the following:Microsoft ProjectMicrosoft Office SuiteMicrosoft Power BIJira and ConfluenceInfrastructure technologies...PMOFull timeContract workTemporary workWork at officeFlexible hours$120k - $145k
...Senior Project ManagerAre you ready to trade your job for a journey? Become a FlyMate!Passion... ...more than 40 nationalities, and in 12 offices world-wide, we're looking for FlyMates... ...Opportunity:We are seeking a Senior Project Manager with deep business transformation...SeniorPMOFull timeLocal areaImmediate startShift work$116.25k - $178.25k
...individual to join the Program Management Office (PMO) and help support the... ...Product Management and technical teams, to formulate and manage... ...OpportunityYou will partner with senior leadership in the PMO and... ...Development ProgramsYou will create project plans, run cross-functional...SeniorPMOWork at officeLocal areaRelocation package
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior IS Technical Project Manager - Project Management Office. Be the first to apply!
- senior digital project manager Boston, MA
- IT project manager Boston, MA
- technical project manager Boston, MA
- remote technical project manager Boston, MA
- digital project manager Boston, MA
- web project manager Boston, MA
- senior IT project manager Boston, MA
- project manager medical device Boston, MA
- bi project manager Boston, MA
- senior project manager Boston, MA



