Senior Product Manager, Provider and RWD Health Systems Applications

Senior Product Manager, Provider and RWD Health Systems Applications

Natera's RWD platform at the clinic connects an ecosystem of real-world evidence, molecular data, and clinical insights to deliver actionable information to physicians. We are seeking a Senior Product Manager to help build and scale physician-facing RWD applications. We seek to unlock the full potential of real-world data to improve treatment outcomes and make molecular results actionable in everyday treatment decisions. In this role, you'll own a physician-facing RWD application for a patient's molecular and clinical journey and workflow integrations behind it, partnering with cross-functional product teams, engineering, AI/ML teams, and clinical teams to deliver intuitive tools centered on enriched patient insights.

What You'll Do

Advance Data Integration and Intelligence

• Collaborate with clinical product management, EMR, user experience product management, marketing, medical and a broad cross functional team to drive product strategy and roadmap,
• Drive integration of genomic tests into the platform (Signatera/ctDNA, hereditary risk, tumor/normal and NGS profiling, liquid CGP, etc.) as part of a unified oncology digitized experience.
• Work closely with AI/ML teams to build applications for patient-level insights and clinic-level insights, including cohort comparison, clinical trial matching, and cohort analytics back to individual patient care.
• Partner with legal, privacy, and security so HIPAA obligations, PHI handling, and data-governance requirements are designed into the product.

Elevate the User Experience

• Own the single- and multi-patient views that bring a patient's molecular results and clinical events together in one physician-facing application.
• Integrate AI-powered clinical trial matching that connects patients and physicians to the most relevant investigational therapies based on molecular, clinical, and patient criteria.
• Help reduce friction points at both the provider and patient level to enroll in clinical trials.
• Partner across Natera to enable EMR/EHR integration and mobile access, ensuring seamless experiences for providers.
• Contribute to an analytics framework that captures user analytics and informs continuous product development.

Enhance the Utility of Genomic Testing

• Support delivery of a physician-facing platform that highlights therapies, tracks treatment response, and monitors disease progression in real time.
• Ship tools and functionality to aid physician collaboration.
• Connect molecular and clinical findings to relevant treatment pathways and outcomes data to make testing more actionable at the point of care.
• Partner with Product Marketing, MSL, Sales, and Clinical Operations on enablement, training, and adoption.

Launch the De-Identified Aggregated Research Platform for Health Systems

• Partner with the Health Systems BU to define, build, and launch a de-identified, aggregated research platform that turns clinic data into a health-system-wide resource for precision medicine and research.

Engage Key Stakeholders

• Engage with physicians, KOLs, and academic collaborators to translate clinical needs into features.
• Help track KPIs centered on the physician experience with RWD at the clinic.
• Support representation of RWD at the clinic at conferences, industry forums, and customer discussions as needed.

What We're Looking For

Required:

• 5+ years of product management or related experience, including experience in healthcare, engineering, genomics, or AI/ML.
• Deep understanding of the oncology domain with direct experience building requirements and collaborating with physicians.
• Experience building clinician-facing software that fits into real clinical workflows.
• Experience delivering AI/LLM-derived clinical data into provider-facing products, including human-in-the-loop review, confidence labeling, and data transparency.
• Backlog ownership: writing and grooming user stories in Jira and driving PM perspective in Agile ceremonies (sprint planning, standups, retros).
• Hands-on with data: comfortable writing SQL (or equivalent) to check status, investigate issues, and measure outcomes, and in the habit of asking 'is this correct, and are we ready to ship?’
• Track record of setting product KPIs and moving them, with specifics on adoption, engagement, and quality.
• Fluency in oncology / genomics clinical concepts (staging, lines of therapy, biomarkers, MRD/ctDNA).
• Commitment to user-centered design thinking, with a track record of translating user needs into intuitive and impactful product experiences.
• Strong written and verbal communication skills with clinical, technical, and commercial audiences.

Preferred:

• Using AI tools day to day to prototype and draft specs.
• EHR integration experience (SMART on FHIR, HL7/FHIR, Epic or other EHR app ecosystems).
• Strong technical fluency; comfortable working with engineers, scientists, and data teams, and reasoning about what AI/ML and LLMs can and can't reliably do.
• Familiarity with PHI-handling applications, HIPAA, or regulated clinical software.
• Familiarity with FDA clinical decision support or SaMD considerations.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$165,800—$207,300 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

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For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page