Senior Program Manager, Informatics R&D

Senior Program Manager

We are seeking an experienced Senior Program Manager to lead complex, cross-functional Informatics R&D programs involving software-intensive medical products, including Software as a Medical Device (SaMD) and Software in a Medical Device (SiMD) deployed on electro-mechanical systems or cloud platforms.

This role owns end-to-end program outcomes across multiple related programs, releases, product lines, or platform capabilities, driving execution, alignment, and decision-making in a regulated medical device environment. The Senior Program Manager operates at both strategic and tactical levels, managing cross-program dependencies, influencing roadmap priorities, aligning and balancing across stakeholder expectations, and ensuring predictable delivery across programs.

To be successful the ideal candidate would be able to operate across ambiguity and detail thinking across programs and portfolios while engaging deeply enough to keep execution moving with rigor, clarity, and accountability.

Role Scope

The Senior Program Manager owns execution and outcomes across multiple related programs, releases, or product areas. This role is accountable for delivery predictability, cross-program alignment, dependency management, and resolution of systemic execution risks.

This includes:

• Owning delivery outcomes across related programs, releases, or product areas.
• Managing cross-program dependencies, sequencing, risks, resources, and tradeoffs.
• Influencing roadmap, release, and prioritization decisions.
• Monitoring and analyzing project trends to predict future operational risks and mitigations.
• Driving alignment across functional leaders, executive stakeholders, and cross-functional teams.
• Facilitating decisions under ambiguity where priorities, constraints, or decision criteria may differ.
• Helping mature program management standards, planning discipline, operating cadence, decision frameworks, and cross-functional accountability.

Essential Duties and Responsibilities

• Lead complex cross-functional Informatics R&D programs involving software, systems engineering, data platforms, cloud technologies, medical device software, and related informatics capabilities.
• Build and maintain integrated program plans covering scope, milestones, schedules, dependencies, resources, risks, decisions, execution priorities, and cross-program tradeoffs.
• Drive program execution through regular operating cadence, clear status reporting, decision tracking, risk management, dependency management, and timely escalation.
• Coordinate deliverables across software engineering, systems engineering, data and informatics, product management, regulatory, quality, verification and validation, clinical, operations, and other stakeholder groups.
• Lead core team meetings, program reviews, and planning discussions, ensuring actions, owners, decisions, risks, and open issues are clearly captured and followed through to closure.
• Lead programs involving SaMD and SiMD products deployed on electro-mechanical systems or cloud platforms, ensuring execution aligns with applicable design controls, quality system expectations, regulatory strategy, and controlled documentation processes.
• Partner with Systems Engineering, Regulatory Affairs, and Quality to coordinate development, verification, validation, risk management, and regulatory deliverables.
• Manage scope, schedule, risks, dependencies, and tradeoffs across related products, releases, and platform capabilities.
• Drive timely decision-making under ambiguity, including alignment on priorities, sequencing, tradeoffs, risks, and resource constraints.
• Support and influence roadmap, release, and portfolio planning for multiple related projects or product lines.
• Help mature Informatics R&D operating practices, including program management standards, planning discipline, execution cadence, decision frameworks, and cross-functional accountability.
• Use modern project planning, development support, and collaboration tools to create visibility, manage execution, track dependencies, and support decision-making.
• Communicate program status, risks, tradeoffs, recommendations, and decisions clearly to functional leaders, executive stakeholders, and cross-functional teams.