Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

ER - RN

PRN Healthcare Services

ER RN

South Carolina is the perfect place for traveling medical professionals to live the life they've always dreamed of. In the summer, South Carolina has fantastic beaches with surf, sun, and sand for you to enjoy. But that's not all, there's also fantastic shopping, great food, historic sites, and great outdoor fun. This is all waiting for you in South Carolina.

Your adventure starts here with PRN Healthcare!

Take control of your career with a travel contract or local contract. Our recruiters are trained matchmakers. By building authentic relationships, we get to know your wants, needs, and everything in between when it comes to your next contract. Armed with this knowledge, we curate opportunities that check your boxes. At PRN our mission is to put our travelers first, make a difference in our communities, and provide exceptional client satisfaction. See why so many are making PRN Healthcare their preferred healthcare staffing company:

  • Top-tier access to premium healthcare jobs nationwide
  • Decades of strong relationships with hospitals and facilities
  • A robust credentialing team that helps locate and pay for pre-employment labs and testing
  • Reliable and consistent support staff who ensure you have an exceptional experience from start to finish
  • Real people are always here to answer your questions and concerns 24/7
  • We make it easy to travel with your fur baby, family, or friend

At PRN Healthcare, our people are our most important asset. We prioritize taking care of the healthcare professionals who spend their careers taking care of patients in our communities. Here are some benefits of working with PRN:

  • Competitive pay
  • Generous housing stipends
  • Medical, Dental, Vision
  • 401(k) with company match
  • Refer-a-friend bonus
Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the ER - RN in Lancaster, SC vacancy
  • MUSC Health is seeking a compassionate and quick-thinking RN to join our Emergency Department Night Team in Lancaster, South Carolina. The ideal candidate will provide safe and competent patient care while supporting patients and families through their health journeys.... 
    Suggested
    Relocation package
    Night shift

    MUSC Health

    Lancaster, SC
    2 days ago
  • The Medical University of South Carolina is seeking a PRN Registered Nurse to provide safe, competent patient care in Lancaster, SC. Responsibilities include educating patients and their families about health conditions and providing emotional support. This position requires...
    Suggested
    Relief
    Flexible hours

    Medical University of South Carolina

    Lancaster, SC
    1 day ago
  • $2,721 per week

     ...THP Healthcare Staffing is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Lancaster, South Carolina....  ...Employment Type: Travel Our Client is currently seeking RN - ER positions in Lancaster, SC for a 4x12 Nights shift. You must have... 
    Suggested
    Weekly pay
    Extra income
    Contract work
    Zero hours contract
    Shift work
    Night shift

    THP Healthcare Staffing

    Lancaster, SC
    6 days ago
  • The Medical University of South Carolina in Lancaster is seeking a compassionate Registered Nurse (RN) for the Emergency Department Night Team. Responsibilities include providing safe patient care, educating families, and offering emotional support. The ideal candidate... 
    Suggested
    Relocation package
    Shift work
    Night shift

    Medical University of South Carolina

    Lancaster, SC
    2 days ago
  • $49 per hour

     ...Stability Healthcare is seeking a local contract nurse RN ED - Emergency Department for a local contract nursing job in Lancaster, South...  ...Type: Local Contract Stability Healthcare is looking for a ER RN contract position in Lancaster, SC. Emergency room (ER) nurses... 
    Suggested
    Hourly pay
    Contract work
    Summer work
    Local area
    Shift work
    Night shift

    Stability Healthcare

    Lancaster, SC
    6 days ago
  • $2,754 per week

     ...Wellspring Nurse Source is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Lancaster, South Carolina....  ...with tax-free stipend amount to be determined. Posted job title: RN ER About Wellspring Nurse Source Wellspring is nurse owned and... 
    Zero hours contract
    Shift work
    Night shift

    Wellspring Nurse Source

    Lancaster, SC
    6 days ago
  • $2,721 per week

     ...THP Healthcare Staffing is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Lancaster, South Carolina....  ...Employment Type: Travel Our Client is currently seeking RN - ER positions in Lancaster, SC for a 4x12 Nights shift. You must have... 
    Weekly pay
    Extra income
    Contract work
    Zero hours contract
    Shift work
    Night shift

    THP Healthcare Staffing

    Lancaster, SC
    2 days ago
  • $2,830 per week

     ...Registered Nurse (RN) | Med/Surg / Telemetry Location: Lancaster, SC Agency: Lancesoft Inc Pay: $2,830 per week Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 6/29/2026 About the Position TravelNurseSource... 
    Long term contract
    Permanent employment
    Full time
    Contract work
    Temporary work
    Work at office
    Shift work
    Night shift

    TravelNurseSource

    Lancaster, SC
    9 days ago
  • $2,293 per week

     ...Registered Nurse (RN) | Telemetry Location: Lancaster, SC Agency: OneStaff Medical Pay: $2,293 per week Shift Information: Rotating - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: ASAP About the Position TravelNurseSource... 
    Hourly pay
    Full time
    Contract work
    Temporary work
    Work experience placement
    Work at office
    Immediate start
    Flexible hours
    Shift work

    TravelNurseSource

    Lancaster, SC
    20 days ago
  • $2,211 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Atlas MedStaff Pay: $2,211 per week Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 6/22/2026 About the Position TravelNurseSource... 
    Hourly pay
    Full time
    Contract work
    Work at office
    Remote work
    Shift work
    Night shift
    Weekend work

    TravelNurseSource

    Lancaster, SC
    10 days ago
  • $2,585 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Accurate Staffing Consultants Pay: $2,585 per week Shift Information: 4 days x 10 hours Start Date: 7/20/2026 About the Position Accurate Healthcare Staffing is currently... 
    Full time
    Shift work

    Accurate Staffing Consultants

    Lancaster, SC
    1 day ago
  • $2,494 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Coast Medical Service Pay: $2,494 per week Shift Information: 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/13/2026 About the Position TravelNurseSource... 
    Daily paid
    Full time
    Contract work
    Shift work

    TravelNurseSource

    Lancaster, SC
    2 days ago
  • $2,416 per week

     ...Registered Nurse (RN) | Neuro ICU Location: Lancaster, SC Agency: Magnet Medical Pay: $2,416 per week Shift Information: Days - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/13/2026 About the Position Purpose of the Position... 
    Full time
    Contract work
    Work experience placement
    Shift work

    Magnet Medical

    Lancaster, SC
    2 days ago
  • $2,585 per week

     ...Registered Nurse (RN) | Med/Surg / Telemetry Location: Lancaster, SC Agency: Accurate Staffing Consultants Pay: $2,585 per week Shift Information: 4 days x 10 hours Start Date: 7/13/2026 About the Position TravelNurseSource is working with... 
    Full time
    Shift work

    TravelNurseSource

    Lancaster, SC
    2 days ago
  • $2,033.82 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: ATC Healthcare Services Pay: Competitive weekly pay (inquire for details) Contract Duration: 13 Weeks Start Date: ASAP About the Position TravelNurseSource is working... 
    Weekly pay
    Daily paid
    Full time
    Contract work
    Local area
    Immediate start
    Flexible hours
    Shift work
    Night shift

    TravelNurseSource

    Lancaster, SC
    1 day ago
  •  ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Fiber Staffing Pay: Competitive weekly pay (inquire for details) Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 6/22/2026 About... 
    Weekly pay
    Extra income
    Full time
    Contract work
    Shift work
    Night shift

    Fiber Staffing

    Lancaster, SC
    21 days ago
  • $2,268 - $2,468 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Ventura MedStaff Pay: $2,268 to $2,468 per week Shift Information: Nights - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/20/2026 About the Position... 
    Weekly pay
    Full time
    Contract work
    Flexible hours
    Shift work
    Night shift

    Ventura MedStaff

    Lancaster, SC
    1 day ago
  • $2,520 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: THP Healthcare Staffing Pay: $2,520 per week Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/20/2026 About the Position... 
    Extra income
    Full time
    Contract work
    Shift work
    Night shift

    THP Healthcare Staffing

    Lancaster, SC
    1 day ago
  • $2,176 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: GetMed Staffing Pay: $2,176 per week Shift Information: Nights - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/20/2026 About the Position GetMed... 
    Full time
    Contract work
    Shift work
    Night shift

    GetMed Staffing

    Lancaster, SC
    1 day ago
  • $2,468 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Cynet Health Pay: $2,468 per week Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/20/2026 About the Position TravelNurseSource... 
    Full time
    Contract work
    Temporary work
    Shift work
    Night shift
    Weekend work

    TravelNurseSource

    Lancaster, SC
    1 day ago
  • $2,304 per week

     ...Registered Nurse (RN) | Telemetry Location: Lancaster, SC Agency: Medical Solutions Pay: $2,304 per week Shift Information: Nights Start Date: 6/15/2026 About the Position A facility in Lancaster, SC is seeking its next amazing RN (Registered... 
    Full time
    Shift work
    Night shift

    Medical Solutions

    Lancaster, SC
    14 days ago
  • $2,246 per week

     ...Registered Nurse (RN) | Telemetry Location: Lancaster, SC Agency: Medical Solutions Pay: $2,246 per week Shift Information: Nights Start Date: 6/8/2026 About the Position TravelNurseSource is working with Medical Solutions to find a qualified... 
    Full time
    Contract work
    Temporary work
    Relief
    Local area
    Shift work
    Night shift

    TravelNurseSource

    Lancaster, SC
    28 days ago
  • $1,554 - $1,723 per week

     ...Registered Nurse (RN) | Med/Surg / Telemetry Location: Lancaster, SC Agency: LRS Healthcare Pay: $1,554 to $1,723 per week Shift Information: Nights Contract Duration: 13 Weeks Start Date: ASAP About the Position TravelNurseSource is... 
    Full time
    Contract work
    Immediate start
    Flexible hours
    Shift work
    Night shift

    TravelNurseSource

    Lancaster, SC
    1 day ago
  • $1,754 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Magnet Medical Pay: $1,754 per week Shift Information: Nights - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/20/2026 About the Position The Registered... 
    Full time
    Contract work
    Shift work
    Night shift

    Magnet Medical

    Lancaster, SC
    1 day ago
  • $2,663 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Infojini Healthcare Pay: $2,663 per week Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 7/20/2026 About the Position RN... 
    Full time
    Contract work
    Shift work
    Night shift

    Infojini Healthcare

    Lancaster, SC
    1 day ago
  • $2,293 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: OneStaff Medical Pay: $2,293 per week Shift Information: Rotating - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: ASAP About the Position We. Are.... 
    Hourly pay
    Full time
    Contract work
    Temporary work
    Work experience placement
    Immediate start
    Shift work

    OneStaff Medical

    Lancaster, SC
    1 day ago
  • $2,468 per week

     ...Registered Nurse (RN) | Med/Surg / Telemetry Location: Lancaster, SC Agency: Cynet Health Pay: $2,468 per week Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 6/22/2026 About the Position TravelNurseSource... 
    Full time
    Contract work
    Temporary work
    Shift work
    Night shift
    Weekend work

    TravelNurseSource

    Lancaster, SC
    24 days ago
  • $2,293 per week

     ...Registered Nurse (RN) | Telemetry Location: Lancaster, SC Agency: OneStaff Medical Pay: $2,293 per week Shift Information: Rotating - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: ASAP About the Position We. Are. OneStaff... 
    Hourly pay
    Full time
    Contract work
    Temporary work
    Work experience placement
    Immediate start
    Shift work

    OneStaff Medical

    Lancaster, SC
    24 days ago
  •  ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Health Advocates Network Pay: Competitive weekly pay (inquire for details) Shift Information: Days Start Date: ASAP About the Position TravelNurseSource is working... 
    Weekly pay
    Daily paid
    Full time
    Local area
    Immediate start
    Shift work

    TravelNurseSource

    Lancaster, SC
    24 days ago
  • $2,211 per week

     ...Registered Nurse (RN) | Medical-Surgical Location: Lancaster, SC Agency: Atlas MedStaff Pay: $2,211 per week Shift Information: Nights - 4 days x 12 hours Contract Duration: 13 Weeks Start Date: 6/22/2026 About the Position Atlas Medstaff... 
    Hourly pay
    Full time
    Contract work
    Work at office
    Shift work
    Night shift

    Atlas MedStaff

    Lancaster, SC
    10 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to ER - RN. Be the first to apply!