Associate Scientist (Dr Ehrlich's Lab - Neurodegeneration and Brain Development) - Neurology

Position available for a Research Scientist in a neuroscience laboratory (Gandy/Ehrlich) focused on study of neurodegenerative diseases, including Alzheimer’s, X-linked dystonia parkinsonism, and Huntington’s disease. Applicants should have experience in molecular, cell and/or animal model systems. Experience with informatics is a plus. These projects involve a broad array of well-established techniques, including mouse breeding and genotyping (with assistance from a research associate and outsourcing of genotyping), molecular biology (e.g. CrispR), histology, cell culture including iPSCs, primary cells and cell lines, microdissection of tissues, RNA and protein preparation, and/or other specialized approaches to study neurodegeneration, including a multi-omic approach.

• Conducts research to develop methodologies, instrumentation and procedures for medical application, analyzing data and presenting findings.
• Designs and conducts complex clinical research studies requiring the determination and evaluation of alternative methods, computational modeling, diagnosis and treatment.
• Plans and directs studies to investigate human or animal disease, preventive methods, and treatments for disease.
• May assist in clinical laboratory operations.
• Follows strict safety procedures when handling materials to avoid contamination.
• Teaches principles of medicine and medical and laboratory procedures to physicians, residents, students, and research staff.
• Confers with health departments, industry personnel, physicians, and others to develop health safety standards and public health improvement programs.
• Develops treatments and designs research tools and techniques.
• Explores subject area and defines scope and selection of problems for investigation through conceptually related studies.
• Develops hypotheses to be tested and methodology for evaluating results.
• Examines the results of clinical trials and adjusts the dosage levels to reduce negative side effects or to induce better results.
• Communicates research results to the scientific community via published papers.
• Develops new proposals for research and obtain support for new and/ or continuing research activities.
• Makes recommendations that have a major impact on extensive scientific research activities.
• Performs other related duties.

• Ph.D. in Biological Science or related field
• Three years experience

Preferred Skills

• 3-years experience following a PhD in neuroscience, cell biology, pharmacology, immunology, biochemistry, molecular biology, pathology, or related discipline.
• Evidence for independent skills in molecular biology, and standard immunoprotein methods (e.g., immunoblotting, immunoprecipitation, immunohistochemistry, ELISA) required. Experience with mouse handling, husbandry and genotyping essential to work with Research Associates.
• Initially, research a topic chosen by the PI, but input from the person in this position is essential.
• Gather and analyze data.
• Prepare scientific reports, manuscripts including figures, and grant proposals, the latter either independently or assistance of an application from the PI.

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $58661 - $98978.78 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.