Physician Assistant/Advanced Registered Nurse Practitioner - Department of Medicine, Division of Metabolism, Endocrinology and Nutrition

Physician Assistant/Advanced Registered Nurse Practitioner

The Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, has an outstanding opportunity for a Physician Assistant/Advanced Registered Nurse Practitioner to join their team.

Reporting to the UWMDI Executive Director, and the Director of Clinical Trial Safety, the Physician Assistant/Advanced Registered Nurse Practitioner is an integral part of our vibrant and growing clinical research team, working closely with principal investigators, research coordinators, and clinical research staff to conduct groundbreaking clinical and translational research studies. This position offers the unique opportunity to contribute to world-class research while developing expertise in advanced clinical and translational research methodologies.

The University of Washington Medicine Diabetes Institute (UWMDI) is a world-renowned research institute dedicated to advancing our understanding and treatment of diabetes and its complications. Located in South Lake Union, Seattle, the UWMDI combines cutting-edge bench and clinical research with a mission to improve outcomes for patients with diabetes across the lifespan. Our clinical research program, led by the Bjornstad-Tommerdahl-Pyle Lab, focuses on diabetic kidney disease, obesity-related kidney disease, and cardiovascular and liver complications in both pediatric and adult populations.

Key Responsibilities

Clinical Research Responsibilities (40%)

• Conduct comprehensive history and physical examinations for research participants
• Determine participant eligibility based on study inclusion and exclusion criteria
• Assess participant safety throughout study procedures and follow-up visits
• Provide detailed study information, clinical results, and education to research participants
• Screen and consent research participants in accordance with IRB protocols
• Serve as lead clinician for assigned research studies
• Document social history, medical history, and physical assessment data
• Make clinical assessments, order laboratory tests, and provide medical oversight
• Review and interpret continuous glucose monitor and insulin pump downloads and provide insulin dosing recommendations
• Perform blood glucose assessments and treatment of hypoglycemia and hyperglycemia
• Monitor and document adverse events (AEs), serious adverse events (SAEs), and protocol deviations (PDs) in adherence with study requirements and regulatory standards

Advanced Research Procedure Supervision and Performance (30%)

• Supervise and perform hyperinsulinemic-euglycemic and hyperglycemic clamps
• Supervise and perform titration of insulin infusions and other IV fluids
• Oversee renal clearance studies using iohexol, para-aminohippurate, and dextran
• Oversee intravenous glucose tolerance tests (IVGTT's), oral glucose tolerance tests (OGTT's), and mixed meal tolerance tests (MMTT's)
• Assist with, supervise, and perform j-wire endovascular biopsies in pediatric and adult participants
• Support cardiovascular research assessments including pulse wave analysis, pulse wave velocity, flow-mediated dilation (FMD), echocardiograms, and ambulatory blood pressure monitoring
• Participate in research kidney and liver biopsy procedures
• Coordinate multiparametric MRI and PET imaging studies of kidney, liver, heart, and brain
• Perform DXA scans and other body composition assessments
• Conduct venipuncture and specialized specimen collection
• Perform laboratory sample processing
• Administer investigational medications and monitor for efficacy and adverse effects

Team Leadership and Coordination (20%)

• Supervise and mentor research coordinators for both pediatric and adult studies
• Provide clinical oversight and guidance to research supervisors and program managers
• Collaborate closely with research nurses at the Clinical Research Unit (CRU) at UWMDI
• Interface with Pediatric Clinical Research Center (PCRC) staff at Seattle Children's Hospital
• Participate in sponsor study initiation visits and regulatory monitoring visits
• Support protocol development and implementation
• Design and implement study recruitment strategies
• Maintain accurate patient charts and study records for research protocols
• Perform specimen preparation, collection, packaging, and shipping as required

Professional Development and Scientific Contribution (10%)

• Participate in multidisciplinary team meetings and research planning sessions
• Opportunities for scientific writing and conference presentations (encouraged but not required)
• Develop and revise study materials including protocols, consent forms, case report forms, standard operating procedures, study operation manuals, and other study-related materials as needed
• Collaborate with data science team members on clinical data integration
• Contribute to grant applications and research proposals
• Mentor junior research staff in clinical research best practices

Note: Competency in specialized research procedures is not expected upon hire. Comprehensive training and ongoing support will be provided to ensure comfort and expertise with all research methodologies.

Required Qualifications

To be considered for this opportunity your application must demonstrate you meet both the minimum qualifications and additional qualifications listed below. Equivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and/or registration.

Minimum Qualifications

• License as an Advanced Registered Nurse Practitioner in the State of Washington or a Physician's Assistant (PA) in the State of Washington, or equivalent legal license/certification.
• Must be eligible to receive hospital staff appointments for adjunct staff membership by the organized medical staff of the hospital under Medical Staff By-Laws for Hospital-based positions.
• Equivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and/or registration.

Preferred Qualifications

• Clinical experience in direct patient care
• Strong attention to detail and ability to follow complex research protocols
• Excellent written and verbal communication skills
• Proficiency in Microsoft Office Suite and electronic medical records systems
• Ability to work with patients from diverse social, economic, and cultural backgrounds
• Flexibility to work occasional weekends and early morning or late evening shifts, as required by study visit schedules
• Previous clinical research experience, particularly in diabetes, endocrinology, or nephrology
• Pediatric clinical experience (significant plus given work at Seattle Children's Hospital)
• Experience with clinical procedures including venipuncture, IV access, and comprehensive physical assessments
• Familiarity with Good Clinical Practice (GCP) guidelines and IRB processes
• Experience working in academic medical centers
• Interest in diabetes complications research and translational medicine
• Background in endocrinology, nephrology, or related specialties

Working Conditions

• Position is fully funded with stable, diversified funding sources
• Work locations include UWMDI in South Lake Union, Seattle and Seattle Children's Hospital
• May work variable hours as dictated by study visits, but not expected to work consistent weekends and holidays
• Potential exposure to contrast agents, investigational medications, and medical procedures involving bodily fluids such as blood and urine
• Must be able to communicate clinical information effectively to clinicians, support staff, patients, and parents
• May perform lifting up to 25 lbs
• Extended periods of computer work and documentation
• Travel between multiple work locations required

About the Team

Join a vibrant, growing research team with internationally recognized leadership in diabetes complications research. This position offers the opportunity to contribute to groundbreaking translational research while working in a collaborative, mentorship-focused environment. The successful candidate will be part of a team with solid and diversified funding sources, ensuring career stability and growth opportunities. Professional development opportunities include scientific writing, conference presentations, and advancement within academic clinical research.

The UWMDI fosters a culture of scientific integrity, innovation, and patient-centered care, providing an exceptional environment for career growth in clinical research. Our team's commitment to mentorship and professional development creates unique opportunities for advancement in academic medicine and clinical research leadership.

Compensation, Benefits and Position Details

Pay Range Minimum: $121,440.00 annual

Pay Range Maximum: $190,080.00 annual

Other Compensation: -

Benefits: For information about benefits for this position, visit