Principal Clinical Study Manager

Stryker is seeking a Principal Clinical Study Manager to join our Neurovascular Division. This is a remote position based anywhere within the United States.

As the Principal Clinical Study Manager , you will lead the planning and execution of complex clinical studies that advance innovation in stroke care. You will collaborate with cross-functional teams, ensure compliance with regulatory standards, and drive operational excellence to deliver high-quality results.

What You Need

• Lead cross-functional clinical project teams, setting study strategy, timelines, budgets, and performance expectations across multiple global trials.

• Design and develop clinical study protocols and investigational plans in collaboration with physician advisors and internal stakeholders.

• Ensure compliant execution of clinical studies aligned with IRB/EC requirements, global regulatory standards, and company policies.

• Own end-to-end study management, including budget development, cost control, and delivery of high-quality, ethical, and publishable results.

• Oversee site selection, qualification, monitoring, and close-out, while directing CRAs and resolving operational and site-level issues.

• Drive study start-up and execution activities, including contracts, site training, CRF design, data management coordination, and CRO oversight.

• Monitor study performance through metrics and reporting, implementing corrective actions and maintaining clear communication with sites and stakeholders.

• Support regulatory submissions (e.g., IDEs, amendments) and lead study reporting, from progress updates through final reports and publication.

Required

• Bachelor's degree in science or health care related field

• 8+ years of relevant work experience in clinical research with minimum 4 years of clinical study management experience

• Experience in the Medical Device or Pharmaceutical industry

• Proven ability to manage complex study programs, budgets, schedules, and cross-functional teams

• Strong leadership, communication, and stakeholder management skills

Preferred

• CCRP, ACRP, PMP, PgMP, or equivalent professional certification

• Experience leading cross-functional teams

Posting Date: 06/02/2026

Posted Date: 06/02/2026

This role will be posted for a minimum of 3 days.

United States of America Pay Ranges:

• USN : $118,000 - $196,700 USD Annual

• US5 : $123,900 - $206,500 USD Annual

• US10 : $129,800 - $216,400 USD Annual

• US15 : $135,700 - $226,200 USD Annual

• US20 : $141,600 - $236,000 USD Annual

• US30 : $153,400 - $255,700 USD Annual

View the U.S. work location and transparency guide ( to find the pay range for your location.

Health benefits include: Medical and prescription drug insurance, dental insurance, vision insurance, critical illness insurance, accident insurance, hospital indemnity insurance, personalized healthcare support, wellbeing program and tobacco cessation program. Financial benefits include: Health Savings Account (HSA), Flexible Spending Accounts (FSAs), 401(k) plan, Employee Stock Purchase Plan (ESPP), basic life and AD&D insurance, and short-term disability insurance. Stryker offers innovative products and services in MedSurg, Neurotechnology, Orthopaedics and Spine that help improve patient and healthcare outcomes. Alongside its customers around the world, Stryker impacts more than 150 million patients annually. Depending on customer requirements employees and new hires in sales and field roles that require access to customer accounts as a function of the job may be required to obtain various vaccinations as an essential function of their role.

Stryker Corporation is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, or protected veteran status. Stryker is an EO employer - M/F/Veteran/Disability.