Upstream/Downstream Manufacturing Scientist

Position Summary

• The Upstream Manufacturing Scientist is a hands-on position responsible for executing mammalian cell culture processes and producing recombinant proteins for a wide range of mammalian based biosimilars. The candidate will be responsible for executing cell culture experiments from 50 L to 2000 L volumes engineering and clinical batches in a cGMP environment. This position requires technical expertise in bioreactor operations, cell biology and knowledge of initiating batch records, protocols, investigations and other technical documents. Work in a team environment to execute batches and can work independently with minimum supervision.

Education and Experience

• Requires a Bachelor or Master’ degree in chemical, biological or biochemical sciences and a minimum of 2-5 years of related experience in the biopharmaceutical industry.
• Previous experience working in GMP and aseptic manufacturing environment.
• Experience working with single use manufacturing consumables such as bags, tube sets, columns and process manifolds.

Upstream (USP) Common questions:

1. Do you have hands on experience on Fermenter / Bioreactor ?
2. Do you have hand on experience on Monoclonal Antibodies(mab’s)?

Job Description: (Downstream)

• The Downstream Manufacturing Scientist is position responsible for executing purification of mammalian cell-based cultures and producing recombinant proteins for a wide range of mammalian based biosimilars. The candidate will be responsible in the purification of 50L to 2000L volumes engineering, clinical and commercial batches in a cGMP environment. This position requires technical expertise in AKTA purification skids or similar, TFF and knowledge of initiating batch records, protocols, investigations and other technical documents.

Requirements

Education:

• Requires a Bachelor or Master’ degree in chemical, biological or biochemical sciences and a minimum of 0-2 years of related experience in the biopharmaceutical industry.
• Previous experience working in GMP and aseptic manufacturing environment.
• Experience working with AKTA Process skids or similar and familiarity of single use manufacturing consumables such as bags, tube sets, columns and process manifolds.
• Possess knowledge to execute engineering and clinical batches; familiar with GMP documentation

Downstream (DSP) Common questions:

1. Do you have hands on experience on TFF/ AKTA?
2. Do you have hand on experience on in depth filtration?