Postdoctoral Fellow - Imaging Technology and Compound Screening, Regev & Singh Labs

Postdoctoral Fellow – High-Throughput Imaging & Computational Methods A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech. The Opportunity High-Plex Assay Development: Develop and optimize high-plex imaging assays that capture rich, multiplexed readouts of cell state and morphology. Computational Methods: Develop computational approaches that expand the information extracted from each sample and improve the efficiency and quality of imaging-based measurements. Large-Scale Screening: Design and execute large-scale compound screens across diverse, disease-relevant model systems, generating systematic, multimodal readouts of cellular response. Data-Driven Discovery: Apply single-cell and multi-omics style analyses to build maps of perturbation relationships and to prioritize the most promising compounds for a given function or activity. Automation & Scale: Leverage laboratory automation and high-throughput workflows to iteratively design, run, and learn from screens at scale. Collaborative Research: Collaborate productively with experimental and computational scientists across departments, present your work to project teams, and contribute to high-impact scientific publications. Professional Development: Join the Genentech postdoctoral training program, which provides an outstanding environment and the opportunity to pursue fundamental scientific questions while building methods that drive breakthrough discoveries in drug development. Who You Are Ph.D. with a proven track record of excellence in single-cell genomics, imaging, bioengineering, biophysics, quantitative biology, or a related field, with hands‑on experimental expertise. Must have advanced at least one key research project as evidenced by a first‑author paper published or accepted in a leading peer‑reviewed journal. Strong hands‑on experience in microscopy and quantitative imaging; experience with multiplexed, high-content, or optical pooled screening approaches is a plus. Computational expertise spanning image analysis and machine learning, with a track record of developing or adapting methods and programming fluently in Python or a comparable language. Independent scientist with outstanding communication skills, a strong passion and commitment to science, who works well within a team. Excited about building new methods to screen compounds at scale and to discover what drives cellular function and activity. Preferred Qualifications Experience developing or deploying multiplexed imaging assays. Experience with AI/ML applied to imaging or other high-dimensional biological data. Experience with laboratory automation, liquid handling, and high-throughput experimental workflows. Experience analyzing large-scale perturbation datasets and integrating multimodal data. Salary and Benefits Expected salary range for this position based on the primary location of South San Francisco, California is $100,000 to $106,500. Benefits details: Relocation benefits are available for this job posting. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. #J-18808-Ljbffr F. Hoffmann-La Roche AG