Principal Scientist, Protein Formulation & DP Development
Denali Therapeutics Inc
Denali Therapeutics Inc in South San Francisco, CA, seeks a Principal Scientist to lead formulation and drug product development for a growing portfolio of protein biologics. You will design studies, establish shelf life, and support comparability across development stages. The role requires a PhD with 10+ years in DP/CMC for protein therapeutics, strong analytical skills, and hands-on LC-MS, HPLC, and cIEF experience. Collaboration with CMOs, QA, and other R&D teams is essential. #J-18808-Ljbffr Denali Therapeutics Inc
$92.6k - $172k
...of Pharma Technical Development (PTD) our organization... ...), clinical supply, formulation, device, packaging,... ....The OpportunityThe Principal Associate Scientist ensures robust... ...pharmaceutical processing are DP liquid filling and... ...-on experience with protein processing, lab...PrincipalFull timeLocal area$159k - $207k
...to patients. We are seeking a Principal Scientist to join our Formulation & Drug Product Development team to serve as a formulation... ...lead for our growing portfolio of protein biologics. This individual will... ..., establish shelf life of DS & DP, assess in-use compatibility,...PrincipalContract workLocal area- ...highly skilled and hands-on Senior to Principal Scientist to join our Protein Science team. This role will focus... ...deep bioconjugation and process development expertise to a novel therapeutic... ...characterization, material requirements, formulation, and study timelines. Communicate...Principal
- Denali Therapeutics invites you to join our Formulation & Drug Product Development team as a Principal Scientist, leading formulation and DP development for a portfolio of protein biologics. You will work with analytical, bioprocess and QA to drive stability, compatibility...Suggested
$140k - $250k
...Principal Scientist, Protein Sciences, Analytical Characterizations September 2025 Department: Technology Position Summary:... ...Manage CROs and external collaborations on analytical development. Prepare precise technical summaries, protocols, and maintain...PrincipalFull timeTemporary workFlexible hours$175k - $200k
...currently developing a robust pipeline of novel protein‑drug conjugate therapies to better address... ...Protein & Peptide/Chemical‑Protein Conjugate Formulation Scientist is a technical leader responsible for the development, optimization, and characterization of stable...$177k - $235k
...) is an Alphabet-founded research and development company whose mission is to harness advanced... ...:We are seeking an innovative Principal Scientist to bridge the gap between traditional... ...years’ post-PhD experience in antibody/protein engineering within the biotech or biopharma...Principal$167.4k - $310.8k
...transforming drug discovery and development. Roche’s Research and Early... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...We are seeking a Senior or Principal Machine Learning Scientist to... ...molecular modalities (e.g., protein sequences, chemical graphs,...PrincipalFull timeLocal areaWorldwideRelocation package$155k - $180k
...biotechnology company pioneering the development of allogeneic chimeric antigen receptor... ...:Allogene Therapeutics is seeking Principal Scientist, Cell Starting Material - Process Sciences... ...viral transduction, cell expansion, formulation).Proven track record of leading...PrincipalFull timeLocal area$155k - $180k
...biotechnology company pioneering the development of allogeneic chimeric antigen receptor... ...is seeking a highly motivated Principal Scientist to lead the Pilot Plant function within... ...viral transduction, cell expansion, formulation).Experience supporting regulatory filings...PrincipalFull timeInternshipLocal area$167.4k - $310.8k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...learning machine learning models for protein and antibodies in zero-shot and few-...Full timeLocal areaWorldwideRelocation packageShift work$162k - $186k
...focused on the discovery, development, and commercialization of targeted protein degradation medicines,... ...an experienced Senior Scientist to join the Analytical... ...responsible for drug product (DP) analytical development... ...for drug product formulations, including amorphous...Contract work$173.1k - $321.5k
...that we all have more time with the people we love.The Senior Principal Scientist serves as the scientific leader for Bioanalytical Strategy... ...critical scientific questions that enable the successful development of cell therapy products. The Senior Principal Scientist will...PrincipalFull timeLocal areaRelocation package$143.29k - $266.11k
The PositionThis role is a vital part of our Cell Therapy Process Development team within Pharma Technical Cell and Gene Therapy Development (PTCC), which is committed to advancing next-generation cell therapies through innovative metabolomics research and media optimization...PrincipalFull timeLocal areaRelocation package$202.8k - $376.6k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...frontier of AI for biology.As a Senior Principal Scientist, you will lead a team...PrincipalFull timeLocal areaWorldwideRelocation package$144.9k - $269.1k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in delivering more innovative and transformative... ...years equivalent experience after PhD (Principal Scientist). The ideal candidate will...PrincipalFull timeLocal areaWorldwideRelocation package3 days per week$147.8k - $274.4k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...motivated and collaborative Senior/Principal Machine Learning Scientist to join the...PrincipalFull timeLocal areaWorldwide$201.3k - $373.8k
...and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at... ...power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative...PrincipalFull timeLocal areaWorldwideShift work$201.3k - $373.8k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... .... We're looking for an exceptional Principal Scientist who can architect how our...PrincipalFull timeLocal areaWorldwide$201.3k - $373.8k
...and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at... ...power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative...PrincipalFull timeWork experience placementLocal areaWorldwideRelocation package$90k - $210k
South San Francisco, CAProcess Sciences - Process Development /Full Time /On-sitePosition SummaryWe are seeking an innovative and highly motivated Supervising Principal Scientist with expertise in cell therapy process development and people management. This individual...PrincipalFull timeFlexible hours$91k - $130k
Job Description Scientist I (Formulation Development) Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians...$200k - $240k
...possible to patients, and who lead with the desire to work on novel ideas. As a Principal Scientist, Potency, you will report to the Sr. Director, Head of Molecular and Potency Method Development. You will either lead or support the development and implementation of...PrincipalTemporary workWork at officeImmediate startWeekend work$180k - $215k
...Principal Scientist, Bioinformatics South San Francisco, California, United States Nkarta is a publicly traded (Nasdaq symbol NKTX)... ...headquartered in South San Francisco, focused on advancing the development of allogeneic, off-the-shelf natural killer (NK) cell...PrincipalWork at officeFlexible hoursShift work$155k - $200k
...using experiments of unprecedented scale. This Position NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development. In this role, you will lead the discovery, development, and qualification of...Principal- Cytokinetics, Inc. in South San Francisco, CA, is seeking an Associate Scientist, Formulation Development, to advance small-molecule therapies across our development pipeline. You will manage internal formulation lab operations and support prototype formulation and drug...
$121.5k - $141.75k
...patients suffering from diseases of cardiac muscle dysfunction. Cytokinetics is seeking a highly motivated Associate Scientist, Formulation Development, to contribute to the advancement of innovative small-molecule therapies across our development pipeline. In this role...- ...Astellas Pharma Inc. is seeking a Scientist I in Formulation Development to design, evaluate, and develop formulations and manufacturing processes for rAAV drug products. The role supports AGT’s pipeline with stability-focused formulation work for clinical use. The candidate...
- About the Role Onsite (South San Francisco, CA). Principal Scientist, Potency; reports to Sr. Director, Head of Molecular and Potency Method Development. Responsibilities Develop and qualify pivotal stage potency, immunoassay, and other cell-based methods to support characterization...PrincipalWork at office
$159k - $207k
## Principal Scientist, Commercial & Late-Stage Cell Culture Process DevelopmentApplylocations: South San Franciscotime type: Full timeposted... ...technical activities for commercial and late-stage process development for Denali’s commercial and near-commercial biologics...PrincipalWork experience placementLocal area
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