Principal Scientist, Protein Formulation & DP Development
Denali Therapeutics Inc
Denali Therapeutics Inc in South San Francisco, CA, seeks a Principal Scientist to lead formulation and drug product development for a growing portfolio of protein biologics. You will design studies, establish shelf life, and support comparability across development stages. The role requires a PhD with 10+ years in DP/CMC for protein therapeutics, strong analytical skills, and hands-on LC-MS, HPLC, and cIEF experience. Collaboration with CMOs, QA, and other R&D teams is essential. #J-18808-Ljbffr Denali Therapeutics Inc
- Denali is seeking a Principal Scientist to lead formulation and drug product process development for its protein biologics portfolio in California. You will drive formulation studies, understand degradation mechanisms, and support scale-up and validation. The role requires...Principal
$140k - $210k
...Senior Scientist/Principal Scientist, Protein Sciences: Analytical & Biophysical Characterizations Department... ...collaboratively with research and development teams to generate critical data... ...teams; ensure alignment with formulation and process development Troubleshooting...PrincipalFull timeTemporary workFlexible hours$159k - $207k
...candidates across all stages of development, we are advancing toward... ...support rapid process and formulation development for our diverse... ...a talented and motivated Principal Scientist to provide strategic technical... ...development experience for protein therapeutics in the biotech...PrincipalContract workLocal area$176.2k - $277.3k
...group based in South San Francisco, CA is seeking a Principal Scientist with expertise in formulation development and candidate selection of peptides. DPS is a... ...Pharmacokinetics, Pharmacology, Product Formulation, Protein Biochemistry, Protein Chemistry, Quality by Design...PrincipalFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$159k - $207k
...therapeutics to patients.We are seeking a Principal Scientist to join our Formulation & Drug Product Development team to serve as a formulation... ...for our growing portfolio of protein biologics. This individual will... ..., establish shelf life of DS & DP, assess in-use compatibility,...PrincipalContract workLocal area$176.2k - $277.3k
...Job Description Principal Scientist in Peptide Formulation (Discovery Pharm Sci) - Position Description... ...Scientist with expertise in formulation development and candidate selection of... ...Pharmacology, Product Formulation, Protein Biochemistry, Protein Chemistry, Quality...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- Denali Therapeutics invites you to join our Formulation & Drug Product Development team as a Principal Scientist, leading formulation and DP development for a portfolio of protein biologics. You will work with analytical, bioprocess and QA to drive stability, compatibility...
$176.2k - $277.3k
...Merck's Discovery Pharmaceutical Sciences group seeks a Principal Scientist to lead peptide formulation development, characterization, and early-stage developability assessment. The role bridges preclinical research with clinical candidate selection across multiple peptide...Principal- IDEAYA Biosciences in South San Francisco seeks a Senior Principal Research Scientist to lead Protein Sciences, supervise a small team, and solve challenging protein-production problems across multiple programs. You will oversee expression, purification, and characterization...Principal
- Merck & Co. in South San Francisco, CA is seeking a Principal Scientist in Peptide Formulation (Discovery Pharm Sci) to lead early formulation development and developability assessments for peptide modalities. You will perform hands-on experiments and drive strategies...Principal
- Genentech in South San Francisco, CA, invites a Principal Scientist in Structural Biology to lead cross-functional efforts integrating cryoEM... ...X-ray crystallography and computational modeling to reveal protein dynamics and ligand interactions. You will guide discovery teams...Principal
- Xaira Therapeutics in the San Francisco Bay Area is seeking a Principal Scientist to lead AI-driven protein engineering for therapeutic proteins and antibodies. You will design, produce, and characterize molecules, guiding experimental strategies and collaborating with...Principal
- ...Xaira Therapeutics seeks a Principal Scientist to lead protein engineering efforts in AI-driven therapeutic discovery. The role combines hands-on... ...Deep expertise in protein engineering and antibody format development Strong knowledge of developability metrics and...Principal
$177k - $235k
...) is an Alphabet-founded research and development company whose mission is to harness advanced... ...:We are seeking an innovative Senior Scientist / Principal Scientist to bridge the gap between... ...) post-PhD experience in antibody/protein engineering within the biotech or biopharma...Principal$159k - $207k
...therapeutic candidates across all stages of development, we are advancing toward our goal of... ...synthesis, purification, formulation, and degradation pathways to resolve technical... ...program teams, collaborating with discovery scientists, process chemists, formulation, quality...PrincipalLocal area$164k - $205k
...leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the... ...with computational design. As a Principal Scientist, you will provide scientific and...PrincipalFlexible hours$159k - $207k
...oversee, and interpret small-scale process development studies that inform large-scale... ...clinical production. Expertise in AKTA protein purification systems, antibody characterization... ...on the collaboration of leading scientists, industry experts, and investors who share...PrincipalWork experience placementLocal area$159k - $207k
...the collaboration of leading scientists, industry experts, and investors... ...countries, we are seeking a Principal Scientist to join our Large Molecule Analytical Development Team to serve as a Commercial... ...glycan analysis) relevant to protein/enzyme‑Fc fusion products Direct...PrincipalContract workLocal area$155k - $180k
...biotechnology company pioneering the development of allogeneic chimeric antigen receptor... ...is seeking a highly motivated Principal Scientist to lead the Pilot Plant function within... ...viral transduction, cell expansion, formulation). Experience supporting regulatory filings...PrincipalInternshipLocal area$197k - $230k
...Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and... ...cross-functional partners including analytical chemistry, formulations, and quality assurancePrepare clear, data-driven reports and...PrincipalContract workShift work$162k - $196k
...focused on the discovery, development, and commercialization of targeted protein degradation medicines,... ...an experienced Senior Scientist to join the Analytical... ...responsible for drug product (DP) analytical development... ...for drug product formulations, including amorphous...Contract work$196k - $242k
...company committed to the discovery, development, and commercialization of transformative... ...are seeking an accomplished Senior Principal Research Scientist in Computational Chemistry with... ...challenging target classes, including protein-protein interactions and allosteric...PrincipalTemporary workWork at officeLocal areaWork from home1 day per week$91k - $130k
Job Description Scientist I (Formulation Development) Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians...- ...role involves hands-on analytical lab work, method development, and product characterization for proteins and oligonucleotides. Responsibilities... ...validation Hands-on lab experience in process or formulation development Ability to work independently and collaborate...Temporary work
- ...Thermo Fisher Scientific seeks a scientist to support parenteral formulation development and drug delivery for novel oligonucleotide therapeutics. The role involves independent formulation preparation, analytical characterization, and data analysis within a customer-based...
$33 - $37 per hour
...science a step beyond through research, development and delivery of life-changing therapies... ...intrathecal, intravitreal). We develop formulations, innovative drug delivery approaches,... ...collaborative, curious, and highly motivated Scientist to support parenteral formulation...Hourly payFull timeContract workTemporary workWork at officeRelocationRelocation package- Genentech is seeking a Principal Engineer/Scientist in Pharma Technical Development to lead scalable microbial (E. coli) process development for biologics. The role supports CCBO and collaborates across R&D, manufacturing, quality, and regulatory groups. The position requires...PrincipalRelocation package
- Role Lead and mentor the Oligonucleotide & Small Molecule CMC Analytical Development team, providing scientific leadership in analytical method development, testing, and characterization for biotherapeutics crossing the blood-brain barrier. Responsibilities oversee analytical...Principal
- Cytokinetics, Inc. in South San Francisco, CA, is seeking an Associate Scientist, Formulation Development, to advance small-molecule therapies across our development pipeline. You will manage internal formulation lab operations and support prototype formulation and drug...
$121.5k - $141.75k
...patients suffering from diseases of cardiac muscle dysfunction. Cytokinetics is seeking a highly motivated Associate Scientist, Formulation Development, to contribute to the advancement of innovative small-molecule therapies across our development pipeline. In this role...
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