Principal Scientist, Protein Formulation & DP Development
Denali Therapeutics Inc
Denali Therapeutics Inc in South San Francisco, CA, seeks a Principal Scientist to lead formulation and drug product development for a growing portfolio of protein biologics. You will design studies, establish shelf life, and support comparability across development stages. The role requires a PhD with 10+ years in DP/CMC for protein therapeutics, strong analytical skills, and hands-on LC-MS, HPLC, and cIEF experience. Collaboration with CMOs, QA, and other R&D teams is essential. #J-18808-Ljbffr Denali Therapeutics Inc
$140k - $210k
Senior Scientist/Principal Scientist, Protein Sciences: Analytical & Biophysical Characterizations Work Location... ...collaboratively with research and development teams to generate critical data... ...teams; ensure alignment with formulation and process development Troubleshooting...PrincipalFull timeTemporary workFlexible hours$159k - $207k
...candidates across all stages of development, we are advancing toward... ...support rapid process and formulation development for our diverse... ...a talented and motivated Principal Scientist to provide strategic technical... ...development experience for protein therapeutics in the biotech...PrincipalContract workLocal area- JLSa2 Therapeutics in South San Francisco seeks a Senior Protein & Peptide/Conjugate Formulation Scientist to lead development, optimization, and characterization of stable formulations for protein and peptide-drug conjugates. The role blends hands-on work with cross-functional...Suggested
$175k - $190k
Principal Scientist / Associate Director, Developability & Protein Sciences About Cartography Biosciences Cartography Biosciences... ...1214, is a T-cell engager in development for colorectal cancer. CBI-12... ...mapping LC-MS), and early formulation development. Help define and...Principal$164k - $205k
...Principal Scientist, Protein Engineering South San Francisco, California, United States Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to...PrincipalFlexible hours$159k - $207k
...therapeutics to patients.We are seeking a Principal Scientist to join our Formulation & Drug Product Development team to serve as a formulation... ...for our growing portfolio of protein biologics. This individual will... ..., establish shelf life of DS & DP, assess in-use compatibility,...PrincipalContract workLocal area- Denali Therapeutics is seeking a Principal Scientist to provide strategic leadership for late-phase and commercial analytical development and extended characterization. You will oversee control strategy development and implementation at CDMOs, lead method qualification...Principal
$197k - $220k
...Alphabet-founded research and development company whose mission is to... ...Calico is seeking a Principal Scientist, Peptide Chemistry to join... ...medicinal chemists, DMPK and formulation scientists to investigate structure... ...design and validation for protein binders. The...Principal- Denali Therapeutics invites you to join our Formulation & Drug Product Development team as a Principal Scientist, leading formulation and DP development for a portfolio of protein biologics. You will work with analytical, bioprocess and QA to drive stability, compatibility...
$175k - $200k
...currently developing a robust pipeline of novel protein-drug conjugate therapies to better address... ...Protein & Peptide/Chemical-Protein Conjugate Formulation Scientist is a technical leader responsible for the development, optimization, and characterization of stable...$164k - $205k
...leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the... .... About the Role We are looking for a Principal Scientist with a strong background in immunology...PrincipalFlexible hours$159k - $207k
...therapeutic candidates across all stages of development, we are advancing toward our goal of... ...synthesis, purification, formulation, and degradation pathways to resolve technical... ...program teams, collaborating with discovery scientists, process chemists, formulation, quality...PrincipalLocal area$197k - $230k
...Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and... ...cross-functional partners including analytical chemistry, formulations, and quality assurance Prepare clear, data-driven reports...PrincipalContract workShift work$177k - $235k
...) is an Alphabet-founded research and development company whose mission is to harness advanced... ...:We are seeking an innovative Senior Scientist / Principal Scientist to bridge the gap between... ...) post-PhD experience in antibody/protein engineering within the biotech or biopharma...Principal$167.4k - $310.8k
...transforming drug discovery and development. Roche’s Research and Early... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...We are seeking a Senior or Principal Machine Learning Scientist to... ...molecular modalities (e.g., protein sequences, chemical graphs,...PrincipalFull timeLocal areaWorldwideRelocation package$167.4k - $310.8k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...learning machine learning models for protein and antibodies in zero-shot and few-...Full timeLocal areaWorldwideRelocation packageShift work$32 - $39.05 per hour
...science a step beyond through research, development and delivery of life-changing therapies... ...intrathecal, intravitreal). We develop formulations, innovative drug delivery approaches,... ...collaborative, curious, and highly motivated Scientist to support parenteral formulation...Hourly payContract workTemporary workWork at officeRelocationRelocation package$180k - $215k
...Principal Scientist, BioinformaticsSouth San Francisco, California, United StatesNkarta is a publicly traded (Nasdaq symbol NKTX), clinical... ...in South San Francisco, focused on advancing the development of allogeneic, off-the-shelf natural killer (NK) cell therapies...PrincipalWork at officeFlexible hoursShift work- Genentech is seeking a Principal Engineer/Scientist in Pharma Technical Development to lead scalable microbial (E. coli) process development for biologics. The role supports CCBO and collaborates across R&D, manufacturing, quality, and regulatory groups. The position requires...PrincipalRelocation package
- Amgen Inc. in South San Francisco seeks a Principal Scientist in Medicinal Chemistry to design, synthesize, and purify novel compounds for potential clinical development. This onsite role participates in Amgen’s IPP PROTAC initiatives and advances targets through innovative...Principal
- ...vision to become the industry‑leading G protein‑coupled receptor (GPCR)-focused drug... ...from a talented team of drug hunters, scientists, and business professionals; and contribute... ...as a team. We are committed to the development of meaningful therapeutics for patients...
$100k - $110k
...vision to become the industry-leading G protein-coupled receptor (GPCR)-focused drug... ...from a talented team of drug hunters, scientists, and business professionals; and contribute... ...as a team. We are committed to the development of meaningful therapeutics for patients...Full time$171k - $223k
...growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective... ...leadership audiences Mentor and guide the scientific work of other scientists across lab and project teams Advance expertise in rare...PrincipalLocal area$164k - $205k
...leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the... ...Therapeutics is seeking a lab-based Principal Scientist in Inflammation and Immunology to join...PrincipalFlexible hours- Thermo Fisher Scientific in South San Francisco, CA, seeks a collaborative Scientist to support parenteral formulation development within the SMP group. You will independently prepare drug products, characterize formulations, analyze data, and guide development through...
$130k - $161k
...Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies... ....Position Description:We are seeking a Senior/Principal Associate Scientist to join an interdisciplinary, collaborative team working...Principal$173.1k - $321.5k
...that we all have more time with the people we love.The Senior Principal Scientist serves as the scientific leader for Bioanalytical Strategy... ...critical scientific questions that enable the successful development of cell therapy products. The Senior Principal Scientist will...PrincipalFull timeLocal areaRelocation package$120.7k - $224.1k
...Genentech provides translational research to inform clinical development in disease areas of Ophthalmology, Metabolism,... ...biomarker approaches. We are seeking a highly motivated Senior Scientist or Principal Lab Group Head to join TM-OMNI to drive biomarker and drug...PrincipalLocal areaRelocation package$147.8k - $274.4k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...motivated and collaborative Senior/Principal Machine Learning Scientist to join the...PrincipalFull timeLocal areaWorldwide$141.5k - $262.9k
...spanning from drug discovery through clinical development. By employing state-of-the-science in... ...:The responsibilities of this Senior Scientist position will :1. Portfolio Strategy &... ..., or CRO environments.Senior Principal Scientist: Ph.D. with >5+ years of industry...PrincipalFull timeLocal areaRelocation package
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