Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Director, Clinical Business Operations

Rapport Therapeutics

Rapport Therapeutics seeks a Director of Clinical Business Operations to lead financial planning, vendor management, and portfolio governance for clinical programs. The role involves building scalable operations infrastructure, overseeing budgets and contracts, and partnering across functions to support the advancement of precision neuromedicines in Boston.

Responsibilities

  • Lead business operations function overseeing budgets, contracts, vendor partnerships, and portfolio governance
  • Develop, manage, and monitor clinical operations budgets with forecasting and spend tracking
  • Negotiate and manage vendor contracts, statements of work, and consulting agreements
  • Establish portfolio-level reporting, dashboards, and governance processes for performance visibility
  • Partner with clinical leadership to evaluate risks, priorities, and resource needs for program support

Requirements

  • Leadership experience managing clinical operations budgets and financial planning
  • Expertise in vendor contract negotiation, management, and governance
  • Demonstrated ability to build and implement scalable business processes and systems
  • Strong cross-functional partnership skills with finance, legal, and clinical teams
  • Experience with portfolio-level reporting, dashboards, and operational metrics
  • Knowledge of regulatory requirements and inspection-readiness standards
Vacancy posted 8 days ago
Similar jobs that could be interesting for youBased on the Director, Clinical Business Operations in Boston, MA vacancy
  • $177k - $278.08k

     ...company to inspire you and empower you to shine? Join us as a Director, Clinical Operations, Oncology based remotely reporting to the Executive...  ...meet Takeda’s obligations described in ICH-GCP and Takeda’s business objectives.The assigned clinical program(s) will be large... 
    Operations
    Minimum wage
    Contract work
    Local area
    Remote work

    Takeda

    Boston, MA
    4 days ago
  • $177k - $278.08k

     ...company to inspire you and empower you to shine? Join us as a Director, Clinical Operations based remotely reporting to the Senior Director, Clinical...  ...Takeda’s obligations described in ICH-GCP and Takeda’s business objectives.The assigned clinical program(s) will be large... 
    Operations
    Minimum wage
    Contract work
    Local area
    Remote work
    Night shift

    Takeda

    Boston, MA
    1 day ago
  • $203k - $245k

    POSITION SUMMARY: Reporting to the Head of Clinical Operations, the Director, Clinical Operations provides strategic and operational leadership for...  ...cross-functional collaboration, team engagement, and business operations. Employees designated as onsite or hybrid who... 
    Operations
    For contractors
    Local area
    Remote work
    Flexible hours

    Rigel Pharmaceuticals

    Boston, MA
    3 days ago
  • $200k - $245k

    Job TitleLocation 221 CRESCENT ST STE 103A, Waltham, MA, 02453-3425, United StatesBase Pay $200,000.00 - $245,000.00 / YearJob Category Clinical OperationsRequired Degree 4 Year DegreeTravel 20%Minimum Experience 12 YearsDescription Requirements
    Operations

    Viridian Therapeutics, Inc.

    Watertown, MA
    5 days ago
  •  ...Role Director of Clinical Operations leading global Phase 2/3 clinical trials in a biopharma setting focused on hematologic diseases. Responsibilities oversee study execution, manage trial managers and vendors, develop and implement clinical strategies, ensure... 
    Operations

    Scorpion Therapeutics

    Watertown, MA
    4 hours ago
  • $207k - $253k

     ...Director, Clinical OperationsMassachusetts - HybridJoin our team in a dynamic hybrid role, offering...  ...Director, Clinical Development Operations, the Director, Clinical Operations is...  ...obligations described in ICH-GCP and Disc's business objectivesTrack key performance... 
    Operations
    Work at office
    Remote work
    Flexible hours
    Shift work

    Disc Medicine

    Watertown, MA
    21 hours ago
  • $175k - $195k

     ...Senior Director, Clinical OperationsJoin our global team dedicated to innovation and initiative...  ...SummaryThe Senior Director, Clinical Operations, is a key member of the Executive Leadership...  ...portfolio reviews.Financial & Business OperationsPartner closely with the Chief... 
    Operations

    Alira Health

    Boston, MA
    1 day ago
  • $183k - $231k

     ...program in Alzheimer’s disease. We are building an early clinical development capability designed to generate rigorous, decision...  ...Therapeutics is seeking an experienced, hands-on Director of Clinical Operations to lead the operational execution of an innovative early-... 
    Operations
    Work from home

    Vesalius Therapeutics

    Cambridge, MA
    3 days ago
  • $253.33k - $286.67k

     ...City Therapeutics is seeking a seasoned, Sr. Director-level subject matter expert to drive the advancement of our clinical programs while upholding our core values and mission. Reporting to the Head of Clinical Operations, the Senior Director will play a pivotal role... 
    Operations
    Full time

    City Therapeutics

    Cambridge, MA
    3 days ago
  • $190k - $220k

     ...Director, Clinical OperationsCambridge, MAAlkeus Pharmaceuticals, Inc. is a clinical-stage biotech company focused on the development of innovative...  ...blindness in the U.S.Position SummaryThe Director, Clinical Operations is responsible for leading and managing global, late-stage... 
    Operations
    Temporary work
    Work experience placement
    Flexible hours

    Alkeus Pharmaceuticals Inc

    Cambridge, MA
    3 days ago
  •  ...GroupContact: ApplicationsEmail: ****@*****.*** SummaryWe are seeking an experienced Associate Director, Clinical Operations to lead the execution of a multinational Phase 2/3 clinical study. This individual will serve as the operational lead for... 
    Operations

    Planet Pharma

    Boston, MA
    4 days ago
  • $210k - $230k

     ...mission to unlock and inspire performance for life. As the Director, Clinical Research Operations, you will lead the clinical operations function...  ...expectations of regulators, investigators, participants, and the business.QUALIFICATIONS:Own the clinical operations strategy... 
    Operations
    Full time
    Work at office
    Remote work
    Relocation

    WHOOP

    Boston, MA
    2 days ago
  • $160k - $240k

    Who we are:Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines...  ...is provided to functional groups for review.Partner with Operational Excellence and assigned Site Engagement Leads to help drive... 
    Operations
    Contract work

    Kymera Therapeutics

    Watertown, MA
    2 days ago
  • $175k - $210k

     ...Monte Rosa Therapeutics is seeking a highly experienced Clinical Operations professional to lead the successful planning, implementation...  ...Reporting to the Head of Clinical Operations, the Associate Director, Clinical Operations will be responsible and accountable for... 
    Operations
    Interim role
    Work at office
    Local area

    Monte Rosa Therapeutics

    Boston, MA
    3 days ago
  • Aditum Bio is seeking a Senior Director, Clinical Operations to lead strategic and operational planning for assigned early-stage clinical development programs across its biotechnology portfolio. Reporting to the SVP, Clinical Development Operations, this role will independently... 
    Operations

    Aditum Bio

    Cambridge, MA
    6 days ago
  • $171.62k - $257.43k

     ...Director, Early Oncology Clinical Operations Technology & Vendor Excellence This is a newly created strategic leadership role, established as part of the...  ...— including EO KPI frameworks, escalation pathways, business review cadences, and contract compliance monitoring.... 
    Operations
    Hourly pay
    Contract work
    Temporary work
    Cambridge, MA
    13 days ago
  • $275k - $285k

     ...Novartis Institutes for Biomedical Research, the firm in-licenses promising therapies that for some reason are not advancing toward the clinic. The firm focuses on the translational phase of medicine to generate data that can support full clinical development, and eventual... 
    Operations
    Full time
    Local area

    Aditum Bio

    Cambridge, MA
    6 days ago
  • $215k - $253k

     ...oversight, and end-to-end execution of clinical trials, while ensuring compliance with regulatory...  ..., supports data integrity, and drives operational efficiencies to ensure studies are...  ...requirements of society, the law, sound business practices and individual dignity. If you... 
    Operations
    Contract work
    For contractors
    Work at office
    Local area
    Relocation

    Collegium Pharmaceutical

    Boston, MA
    2 days ago
  • $255k - $290k

    About Parabilis Medicines Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary...  ...us on LinkedIn. What's the opportunity? The Senior Director, Clinical Operations will provide strategic and operational leadership across... 
    Operations
    Work at office
    Local area
    Remote work
    Shift work

    Parabilis Medicines

    Cambridge, MA
    4 days ago
  •  ...living with serious and rare diseases, and we are getting closer to achieving this goal every day.Reporting to the VP, Clinical Operations, the Director, Clinical Operations is responsible for leading projects to support the execution of clinical studies aligned with the... 
    Operations
    Temporary work
    Work at office
    Local area
    Immediate start
    3 days per week

    Viridian Therapeutics

    Waltham, MA
    3 days ago
  • $219k - $235k

    The Director of Clinical Operations in the Discovery Medicine and Pharmaceutical Sciences plays a central role in the execution of Phase 1 clinical...  ...Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma... 
    Operations
    Work at office
    Local area
    Flexible hours
    3 days per week

    Alkermes

    Waltham, MA
    1 day ago
  • $140k - $165k

     ...services company powering the acceleration of clinical research to transform patient outcomes....  ...-wide.As the Senior Manager, Clinical Operations- GI at Iterative Health you will serve...  ...outcomesComfortable navigating evolving business priorities and opportunitiesBenefits... 
    Operations
    Temporary work
    Work at office
    2 days per week

    Iterative Scopes

    Cambridge, MA
    5 days ago
  • $164k - $199k

     ...healthcare discipline, with 8+ years of clinical operations experience, including 4+ years as a...  ...and oversight of Clinical Operations, Business Optimization and TMF functions. Meet our...  ...Talent Partner:Ben Hoogheem - Senior Director, Head of Talent ManagementAs Head of Talent... 
    Operations
    Contract work
    Local area

    Tessera Therapeutics

    Somerville, MA
    5 days ago
  • $124k - $280k

     ...providing consulting services on optimising operational efficiency and effectiveness. These...  ...processes, improve productivity, and drive business performance.As part of the Corporate...  ...trusted relationships and aligning diverse clinical, operational, and functional teams Guide... 
    Operations
    Full time
    H1b

    PwC

    Boston, MA
    4 days ago
  • $119k - $179k

     ...Clinical Operations ManagerThe Clinical Operations Manager serves as a dedicated functional expert within a cross-functional team, contributing...  ...teams, including managing research timelines across the business from inception to publication.Work across the Research/EvGen... 
    Operations
    Full time

    Verily

    Boston, MA
    5 days ago
  •  ...settings. Corporate sustainability – both environmental and social – is at the forefront of our decision making. About the Role The Clinical Operations Manager will play a critical role in the planning, execution, and oversight of Nanopath’s clinical studies. This role... 
    Operations
    Full time
    Work at office
    Remote work

    Nanopath

    Cambridge, MA
    5 days ago
  • $90k - $110k

     ...Clinical Study Operations ManagerBeacon Biosignals is transforming precision medicine for the brain, from clinical development to clinical care...  ..., psychiatric, and sleep disorders. Our Diagnostics business is building the most comprehensive at-home platform for precision... 
    Operations
    Contract work
    Work experience placement
    Work at office
    Remote work

    Beacon Biosignals

    Boston, MA
    5 days ago
  • $120k - $200k

     ...and communities.The RoleA Senior Product Manager for Veeva Clinical Operations will own the product strategy and roadmap for key applications...  ...success, inform data-driven decisions, and demonstrate business impact.Stay current with regulatory changes affecting the clinical... 
    Operations
    Work at office
    Local area
    Remote work
    Work from home
    3 days per week

    Veeva Systems

    Boston, MA
    4 days ago
  • $213k - $240k

     ...Director, Clinical OperationsWaltham, Massachusetts, United StatesAbout Us:Oruka Therapeutics...  ...nimble and flexible Director of Clinical Operations who has a track record of achievement...  ...ensuring alignment with program goals and business objectives.Proactively identify... 
    Operations
    Contract work
    Flexible hours
    3 days per week

    Oruka Therapeutics

    Waltham, MA
    1 day ago
  • $228.8k - $343.2k

     ...has an exciting opportunity to join the team as our Senior Director, Clinical Sciences. This is a hands-on leadership role that combines functional...  ...closely with Clinical Development physicians, Clinical Operations, Biostatistics, Clinical Pharmacology, Pharmacovigilance,... 
    Operations

    Tango Therapeutics

    Boston, MA
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Director, Clinical Business Operations. Be the first to apply!