PRINCIPAL SYSTEMS ARCHITECT, IS&T Research Computing
$150.4kBoston University
CategoryCharles River Campus --> Information TechnologyJob LocationBOSTON, MA, United StatesTracking Code26500998960407Posted Date4/7/2026Expected Hiring Range Minimum$150,400.00Expected Hiring Range Maximum$180,000.00The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, training and internal pay comparison. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.Position TypeFull-Time/RegularBoston University Information Services & Technology (IS&T) is seeking applicants with diverse skills and experiences to join our innovative and inclusive community. Join us as a Principal Systems Architect, where you will lead the design, development, and operations of Boston University's cloud-based research computing infrastructure, serving as the senior technical authority for IaaS, PaaS, and SaaS platforms that support data intensive research across multiple disciplines.You will combine deep hands-on operational expertise with strategic vision to architect next generation cloud systems whose impact will shape future University and communitywide research computing decisions. You will also oversee and advance major initiatives such as the New England Research Cloud (NERC) and its follow on projects, collaborating closely with partner universities and industry partners to develop shared research computing capabilities and standards. You will work closely with partner universities and industry partners to advance shared research computing goals.Required SkillsBachelor's degree or equivalent work experience. Experience: 7+ years of relevant experience.We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, natural or protective hairstyle, religion, sex, age, national origin, physical or mental disability, sexual orientation, gender identity, genetic information, military service, pregnancy or pregnancy-related condition, or because of marital, parental, or veteran status. We are a VEVRAA Federal Contractor.
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$142.5k - $256.5k
The Role:Moderna’s Therapeutics Research group is seeking a talented, experienced, and highly motivated Principal Scientist to support computational protein design across therapeutic research. This role will focus primarily on the design and optimization of T cell receptors...PrincipalPermanent employmentFull timeWork at officeWork from home$160k - $200k
...diseases. Role We are seeking an exceptional Associate Principal or Principal Computational Biologist / Bioinformatics Data Scientist with deep expertise... ...with biologists and chemists to translate complex research questions into well-designed omics studies, and you will...PrincipalMinimum wageLocal area$166.77k - $202.09k
...patient benefit. IPS conducts applied computational research in areas that include genomic, structural... ...informatics, computational and systems biology, patient selection and translational... ...to Chat with Ripley. R1603662 : Principal Scientist, Computational Biology #J-1...PrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$138.6k - $257.4k
...Pathology and Biomarkers group within Oncology Translational Research at Novartis Biomedical Research is seeking an accomplished Imaging... ...and technical leader with expertise in digital pathology, computational image analysis, AI/ML, and tissue-based oncology biomarkers....PrincipalFull time- QuEra Computing Inc. in Boston, MA is seeking a Ph.D. level scientist to contribute... ...to advance quantum computing systems. The ideal candidate will have... ...quantum platforms, proven ability in architecting complex systems, and a solid research background in AMO physics. This...
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Job title: Senior Principal Scientist/Principal Scientist, Real-World... ...'s Target, Disease and Systems Biology (TDSB) team and become... ...Working alongside world-class computational and experimental scientists,... ...meets bold, AI-powered research. In R&D, you’ll drive breakthroughs...PrincipalFull time$146k - $236k
...legacy of founding cutting-edge science and computational ventures, harnessing recent advances in... ..., and data to accelerate fundamental research and create a portfolio of AI-first... ...Pioneering Intelligence (PI) is building AI systems that accelerate translational decision...Principal$160k - $200k
Dewpoint Therapeutics in Boston is looking for an Associate Principal or Principal Computational Biologist to drive innovative drug discovery through multi-omics data analysis. You will collaborate with a team to design, execute, and interpret bioinformatics analyses that...Principal$270k - $300k
...and peak performance.We are seeking a Principal AI Researcher to join our Foundation AI team. This team... ...reported inputs to create scalable AI systems that understand human physiology and... ...at WHOOP, shaping the platform, compute, and infrastructure choices the team operates...PrincipalFull timeWork at officeRelocation- SummaryWe are seeking a Principal Systems Engineer to play a critical role in aligning engineering... ...development of large-scale quantum computers.This role sits at the intersection of... ...tools.Experience working closely with research or experimental teams.Exposure to quantum...Principal
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$148.19k - $231.98k
...Salesforce.The RoleAs a Core Technical Architect, you are a pre-sales, customer-facing expert... ...applications, delivery, and end-to-end system architecture. Coding experience and... ...Strategic & Soft Skills Bachelor’s degree in Computer Science, STEM field, or equivalent...PrincipalFull time$140.63k - $281.25k
Catapult Sports is seeking a Principal Computer Vision & Tracking Engineer based in Boston. This role involves leading a team to develop computer vision systems that provide athlete performance insights. Candidates should have 8+ years of experience in software engineering...Principal- Brigham and Women's Hospital, Inc. seeks a doctoral-level Senior Computational Scientist to provide intermittent leadership for epigenomics projects and to maintain a proprietary set of analytical frameworks. This per-diem role supports manuscripts in revision and publication...PrincipalDaily paid
- QUALIFICATIONSBachelor’s or master’s degree in computer science, engineering, or a related... ...command of data engineering, AI/ML systems, and deployment architecturesProven... ...and your family.WHAT YOU'LL DOAs a Principal AI Solution Architect at McKinsey, you will combine deep...PrincipalApprenticeshipImmediate startEasy workFlexible hours
- Job DescriptionJob Description: Principal, Business Consulting -Solution Architect The vision of the Data &Analytics team is to help our clients become Data... ...& Querying: SQL, NoSQL, Python, Distributed Computing…Analytics & BI Integration: Integration with BI Tools...PrincipalFull timeTemporary workWork experience placementLocal area
- Bristol Myers Squibb seeks a Principal Scientist, Computational Biology in Cambridge, MA to join the Neuroscience, Immunology, and Cardiovascular discovery team within IPS. You will apply advanced computational methods to multi-omics and single-cell data to drive early...Principal
$148.19k - $231.98k
...The Role As a Core Technical Architect, you are a pre-sales, customer-facing expert. You... ...applications, delivery, and end-to-end system architecture. Coding experience and willingness... ...& Soft Skills Bachelor’s degree in Computer Science, STEM field, or equivalent...Principal$170k - $200k
..., and oral exposure. The candidate must be able to integrate computational modeling, structural information, biophysical data, and biological... ...as well as with new patent application filings. ~ Lead research team or serve as medicinal chemistry lead from concept...Principal$126k - $234k
...#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal Scientist... ...clinical programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK... ...Prior experience with the integration of computational modeling and biological concepts is required...Principal$169.8k - $355.4k
...Job Description The computer vision team is responsible for growing our capabilities in image analysis and recognition. Our goal is... ...learning, and image processing Proven track record of leading research and development projects Strong understanding of machine...PrincipalTemporary workFlexible hours$122.25k - $176.58k
Job Title: Principal Scientist, Systems and Disease BiologyLocation: Cambridge, MAAbout the JobAs a Principal... ...Systems Biology function at Sanofi Research, is dedicated to delivering first-in... ...of innovative algorithms and computational models.Leading projects involving internal...PrincipalFull time$128k - $192k
...difference, there’s only one choice.Principal Machine Learning Scientist... ...activities, improving system performance through data analysis... ...(chemists, biologists, computational/data scientists, R&D leadership... ...related to drug development research, including biochemical,...PrincipalLocal area- ...Principal Analytics Solutions Architect, US AGS Specialist SA Job ID: 10496100 | Amazon Web Services, Inc.... ...on Amazon’s industry leading cloud computing platform. We are looking for an... ...designing entirely new cloud-based systems. Do you enjoy solving novel and unique...PrincipalWorldwideFlexible hours
$108.5k - $201.5k
...patients’ lives around the world. As a Principal Scientist I or II, Oligonucleotide Chemistry... ...medicines in a dynamic and fast-paced research environment. This is an exciting... ...Laboratory, Chemical Synthesis, Chemistry, Computational Chemistry, Creativity, Data Analysis,...PrincipalFull timeLocal areaWorldwideFlexible hours$142.5k - $256.5k
...programs, and rapid maturation of computationally designed candidates.The... ...as well as other members of Research, to advance novel candidates... ...deploy scalable screening systems that replace resource-intensive... ...ownership consistent with a Principal Scientist role.Here’s What...PrincipalPermanent employmentFull timeWork at officeWork from home- ...immunotherapies for cancer. Powered by computational protein design and proprietary technologies... ...competitive therapeutics, diagnostics, research tools, and/or technological... ...Therapeutics is seeking an experienced Principal Scientist to help establish and advance...PrincipalFull timeLocal area
- ...Scientist-Principal Scientist, Protein Design & Structure Boston, MA Superluminal... ...speed using a combination of deep biology, computational and medicinal chemistry, machine... ...internal/external meetings, and publish research findings. Required Qualifications...Principal
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