Director, Data Architecture and Analytics (Waltham)

Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases. Our core business strategy combines our experienced leadership team with a disciplined product candidate acquisition approach to identify, acquire and develop product candidates globally that we believe can provide superior clinical benefits to patients living with autoimmune diseases. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. We believe that obexelimab’s unique mechanism of action and self-administered, subcutaneous injection regimen may broadly and effectively address the pathogenic role of B cell lineage in chronic autoimmune disease. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Zenas’ earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcγRIIb monoclonal antibody.

We are seeking top talent who share our commitment to patients and have a track record of success in acquiring, developing and commercializing products across the globe. Our colleagues have an opportunity to engage in a fast-paced learning environment and experience individual and organizational success as we work towards becoming a global immunology and autoimmune disease leader, while living our values of Transparency, Relationships, Urgency, Excellence and Innovation – TRUE Innovation !

Position Summary

Zenas is currently looking for an individual to join our growing IT team. Reporting to the Executive Director of Commercial Systems, the Director, Data Architecture & Analytics will play a significant role, starting with Commercial related data, in crafting the overall data architecture within Zenas. This individual will leverage their expert specialist skills and knowledge to architect, design, and implement data driven solutions across the Zenas technology landscape. While the initial focus will be Commercial data in support of our first product launch, the scope of this role is expected to expand over time to encompass other enterprise data across Zenas.

Key Responsibilities

• Lead the design, development, implementation, and maintenance of complex data solutions across Pharma domains, including Commercial and Medical Affairs
• Serve as primary point of accountability for the data warehouse and data aggregation vendors, managing both through implementation and into steady-state operations
  • During implementation: oversee vendor delivery against project plans, timelines, and requirements; manage issue resolution and change requests; ensure solutions are built to spec and ready for go-live
  • In ongoing operations: own the day-to-day vendor relationship, including performance against SLAs, platform stability, enhancement requests, contract/renewal management, and escalation resolution
• Ensure channel partner data feeds (e.g., HUB, specialty pharmacy, 3PL, distributor/wholesaler) flowing through these platforms are monitored for accuracy and completeness; establish quality checks and hold vendors accountable to SLAs for feed reconciliation and issue resolution
• Partner with third-party vendors to implement and govern master data management solutions, providing ongoing oversight of the deployed solution
• Lead the development of, advise on, and manage data integration solutions across multiple platforms, leveraging tools such as Informatica, MuleSoft, Talend, Boomi, Azure Data Factory, or Fivetran
• Identify opportunities for platform improvement and recommend data warehouse/AI solutions to meet immediate and long-term business needs
• Provide technical leadership and strategic direction on data technologies, standards, processes, and architecture across the enterprise
• Establish a scalable data architecture and roadmap that extends beyond the initial Commercial launch to support additional enterprise data domains over time
• Troubleshoot data issues and proactively design solutions to prevent recurrence
• Design and implement data architecture to support BI and reporting initiatives
• Serve as a trusted advisor to internal stakeholders, including senior commercial and medical affairs leadership

Qualifications

• Bachelor's degree in Computer Science or related field; MBA/MS preferred, or equivalent experience
• 12+ years of experience in technical leadership across Business Technology, Data Strategy, Data Warehousing, Data Governance, or Cloud technology
  • Hands-on experience with cloud platforms (AWS, Azure) and data technologies such as Snowflake, Databricks, Glue, S3, Amazon EMR, and Redshift
• 8+ years of experience in Pharma data management with a Commercial focus, including data warehousing and master data management
• Strong experience managing third-party data platform vendors, including RFP/contract processes, SLA management, and vendor governance
• Familiarity with channel partner data sources (HUB, specialty pharmacy, 3PL, distributor/wholesaler) and associated data quality/accuracy considerations

The position is eligible for a competitive compensation and benefits package.

Zenas is committed to fair and equitable compensation practices. The base salary pay range for this role is $183,300 to $229,174. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.

Zenas believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Zenas’ competitive total rewards strategy that also includes annual performance bonus, equity, full range of benefits and other incentive compensation plans.

Zenas BioPharma is proud to be an equal opportunity employer. We are committed to fostering an environment where diversity is valued. All qualified applicants will receive consideration for employment based on merit, qualifications and the needs of the business.