Senior Internal Auditor II - IT (San Diego/Hybrid)

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people. The Senior Internal Auditor II – IT is a key member of Illumina’s Internal Audit function and reports to the Associate Director, Internal Audit – IT. This role supports both the planning and execution of the Company’s SOX compliance program and IT advisory engagements for system implementations. Full‑time position (Monday through Friday) with an expectation of 2–3 in‑office days per week. Candidates must reside in the San Diego area and be able to commute to our offices. Relocation assistance is available for employees who must move, to be completed within a three‑month period or mutually agreed upon time. Key Responsibilities Lead and/or execute assigned components of the Company’s SOX compliance program, including risk assessment, scoping, walkthroughs, and testing of IT general and application controls Collaborate with external auditors to support SOX‑related assurance activities and SEC reporting timelines Independently evaluate control deficiencies, perform root cause analysis, and partner with control owners in their design and implementation of remediation actions, through to closure Review and maintain high‑quality SOX documentation, including narratives, process flowcharts, control descriptions, and risk and control matrices Support periodic updates to control design to improve efficiency, effectiveness, and scalability Build strong, trusted relationships with cross‑functional partners at various levels of management Maintain Internal Audit systems and tools infrastructure and implement departmental technology initiatives Assist with and/or lead departmental initiatives, special projects, and Finance‑wide initiatives as needed All About You You are a business‑and tech‑savvy audit professional with strong analytical and critical thinking skills. You thrive in a fast‑paced environment, adapt quickly to change, and take pride in delivering high‑quality work. You communicate clearly and confidently, can work independently or as part of a team, and build effective relationships across the organization. Requirements Typically requires a minimum of 8 years of progressive audit experience in a public accounting firm and/or multinational public company with a bachelor’s degree; or 6 years and a master’s degree; or a PhD with 3 years of experience; or equivalent experience. Experience designing, monitoring, and evaluating internal controls in a multinational environment. Knowledge of IT General Controls, Application Controls, cybersecurity, and ERP environments (SAP preferred). Experience working in life sciences, biotech, technology, or pharmaceutical industries preferred. Core Capabilities Demonstrates the highest standards of ethics and integrity Strong analytical and critical thinking skills, with the ability to assess risk and drive sound conclusions Experience analyzing large datasets and using data analytics to generate meaningful insights Proficient with audit management tools (such as AuditBoard, Optro, or TeamMate) and process flowcharting tools Experience leveraging AI tools to improve efficiency and effectiveness Excellent written and verbal communication skills, including the ability to clearly discuss risks, findings, and recommendations with senior management Strong project management skills, with the ability to balance multiple priorities and meet deadlines while delivering high‑quality work with minimal revisions Education & Certifications Bachelor’s or Master’s degree in Computer Science, Finance, Accounting or equivalent CISA, CISM, CIA, or equivalent professional certification required Compensation and Benefits Base salary range: $107,700 – $161,500. Employees may receive variable cash programs (bonus or commission) and equity as part of compensation. Benefits include health/dental/vision coverage, paid time off, retirement benefits, and other standard benefits. The role is hybrid (San Diego office) and full‑time Monday through Friday with 2‑3 in‑office days. Legal & EEO Statement Illumina is an equal‑opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact View email address on click.appcast.io. To learn more, visit: The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship. #J-18808-Ljbffr