Scientist (LNP Formulation/Nucleic Acid)

Job Description

Scientist (LNP Formulation/Nucleic Acid)

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Russell Tobin is partnering with a leading biotechnology organization to identify a Scientist to support formulation development and characterization of lipid nanoparticles (LNPs) for nucleic acid delivery. This hands-on laboratory role involves optimizing formulations, executing screening studies, and supporting non-viral delivery research.

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Responsibilities

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· Formulate and optimize targeted and non-targeted lipid nanoparticles (LNPs) encapsulating nucleic acids, including mRNA, siRNA, and DNA, for in vitro and in vivo studies.

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· Characterize LNP formulations and evaluate formulation performance under the guidance of senior formulation scientists.

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· Execute Design of Experiments (DoE)-based screening campaigns to identify optimal LNP compositions and processing parameters.

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· Collaborate with cross-functional teams to fulfill formulation requests and support research objectives.

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· Assist with early-stage formulation development and downstream processing, including cryoprotection, scale-up, and stability studies.

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· Maintain detailed and accurate laboratory records documenting formulation procedures, experimental results, and observations.

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· Analyze, interpret, and present experimental data to the formulation team.

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· Support routine laboratory operations, including inventory tracking, supply ordering, buffer preparation, and autoclaving.

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Requirements

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· Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering, or a related discipline with 5+ years of biopharmaceutical industry experience , or a Master's degree with 2+ years of industry experience .

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· Minimum 2 years of hands-on laboratory experience in LNP formulation and nucleic acid encapsulation .

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· Proficiency in LNP characterization techniques, including Dynamic Light Scattering (DLS), zeta potential, and RiboGreen assays.

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· High proficiency in Microsoft Excel; experience with statistical and data analysis software such as JMP or Prism is preferred.

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· Strong experimental, analytical, and organizational skills with a focus on reproducibility and data integrity.

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· Excellent written and verbal communication skills and the ability to collaborate effectively in a fast-paced laboratory environment.

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· Experience preparing targeted LNPs using antibodies or fragments such as mAb, Fab, scFv, or VHH is highly desirable.

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· Experience with immune cell delivery is a plus.

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Additional Details:

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• Location model: On-site — San Diego, CA
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• Schedule: 1st shift, standard business hours
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• Position Type: 3-month contract with a very high possibility of extension
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• Pay range: $45–$48/hr , depending on experience.
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APPLY NOW!

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Russell Tobin is a professional recruitment and staffing advisory firm that connects job seekers and employers across various industries. We are a staffing arm of Pride Global. Affiliates include Russell Tobin, Pride Health, Pride Now and Pride One.

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For workers in the United States, PrideGlobal and it's affiliates offers eligible employee’s comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance and hospital indemnity), 401(k)-retirement savings, life & disability insurance, an employee assistance program, legal support, pet insurance and employee discounts with preferred vendors.

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Equal Employment Opportunity

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PrideGlobal and it's affiliates are an equal opportunity employer. We do not discriminate on the basis of the race, religious creed, color, national origin, ancestry, physical disability, mental disability, reproductive health decision making, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, age, sexual orientation, veteran or military status, or any other characteristic protected by applicable federal, state, or local law.

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Fair Chance Employment

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PrideGlobal and it's affiliates are a Fair Chance employer. We consider all qualified applicants, including those with criminal histories, in a manner consistent with applicable state and local Fair Chance laws and ordinances, including, the California Fair Chance Act and all applicable local Fair Chance ordinances.

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Accommodations

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We are committed to providing reasonable accommodations to applicants and employees with disabilities. If you require a reasonable accommodation to participate in the application or interview process, or to perform the essential functions of this role, please contact us.

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Only applicable for San Francisco Candidates : Under the San Francisco Lactation in the Workplace Ordinance, we will provide written notice of lactation accommodation rights, and this notice will automatically be given upon hiring, any inquiry of parental leave or lactation accommodation.

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Only applicable for Kentucky positions: For this type of employment, state law requires a criminal record check as a condition of employment. This applies to direct care staff (Examples: RN, LPN, Nurse Aides, Therapists) referred to Kentucky nursing facilities, assisted living communities, or long-term care facilities, in accordance with KRS 216.793.