Lead Purification Scientist for Large-Molecule Development
Scorpion Therapeutics
Scorpion Therapeutics in the United States seeks a senior scientist to lead purification process characterization and validation for large molecule development, supporting IND/BLA submissions. You will design and execute chromatography, filtration, and analytical studies; author protocols, review data, generate reports, and prepare IND/BLA sections; and coordinate with internal teams and CMOs for late-stage data transfer to manufacturing. #J-18808-Ljbffr Scorpion Therapeutics
- Role Lead purification process characterization and validation for large molecule development, supporting IND/BLA submission. Responsibilities design and execute chromatography, filtration, and analytical studies author protocols, review data, generate reports, and prepare...Suggested
- ...The Biologics CMC Development team at AbbVie in the... ...of highly experienced scientists and managers who have... ...a member of the CMC Purification Development group, you... ...strategy as a functional lead on cross-functional... ...multispecifics, antibody-like molecules, and other complex...SuggestedFull timeContract workLocal area
- Role Lead and mentor the Oligonucleotide & Small Molecule CMC Analytical Development team, providing scientific leadership in analytical method development, testing, and... ...knowledge of oligonucleotide synthesis, purification, and impurity profiling; experience coordinating...Suggested
$159k - $207k
...Responsibilities: Serve as downstream purification technical lead for commercial manufacturing... ...interpret small-scale process development studies that inform large-scale manufacturing decisions, support... ...on the collaboration of leading scientists, industry experts, and investors...SuggestedWork experience placementLocal area- Scorpion Therapeutics seeks a senior scientist to lead and mentor the CMC Analytical Development team, overseeing method development, testing, and characterization... ...strategy across oligonucleotide and small-molecule programs, validate methods, and coordinate CROs/CDMOs...Suggested
- ...Francisco Bay Area (South San Francisco) is seeking an senior scientist for Biologics CMC Purification Development. You will design and optimize drug substance purification processes for complex biologics and lead technology transfers to GMP manufacturing sites. You will...Contract work
- ...close collaboration with medicinal chemistry and cross-functional teams. The successful candidate will hold a PhD in analytical chemistry with 5+ years in drug discovery, focusing on HPLC/SFC purification, method development, and CRO management. #J-18808-Ljbffr IDEAYA
$164k - $205k
...Principal Scientist, Protein Engineering South... ...drug discovery and development. The company is leading the development of... ...evaluate designed molecules. You will engineer,... ...biopharma R&D supporting large-molecule... ...formats, production, purification, and characterization...Flexible hours- ...for an Oligonucleotide Scientist II for a contract... ...oligonucleotide therapeutics, large molecule drug discovery, would... ...-up synthesis of lead molecules and... ...chemistry, oligonucleotide purification and characterization... ...experience in research and development of RNAi therapeutics...Contract work
$124.3k - $230.9k
...leader who will be supporting small molecule projects in discovery and development. The DMPK group is dedicated to... ...pharmacology and regulatory to optimize leads, select clinical candidates,... ...supporting diverse modalities (small/large molecules, peptides, degraders, conjugates...Full timeLocal areaRelocation$124.3k - $230.9k
...enabling the discovery, development and commercialization... ...properties of small molecule drug candidates. We accomplish... ...to optimize leads, select clinical candidates... ...a Ph.D. level Senior Scientist who is highly... ...diverse modalities (small/large molecules, peptides, etc...Full timeLocal areaRelocation$167.4k - $310.8k
...sciences are transforming drug discovery and development. Roche’s Research and Early... ...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... ...we are driving a paradigm shift in how large molecule drug discovery is conducted. Our...Full timeLocal areaWorldwideRelocation packageShift work$201.3k - $373.8k
...transforming drug discovery and development. Roche’s Research and Early... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...driving a paradigm shift in how large molecule drug discovery is conducted.... ...:Drive portfolio impact by leading the application of machine...Full timeLocal areaWorldwideShift work- Merck & Co. in South San Francisco seeks a Principal Scientist to lead in vivo antibody discovery strategies within the Discovery Biologics... ...will drive cross-functional projects, oversee technology development, and mentor teams to advance challenging targets with aggressive...
- Genentech is seeking a Principal Scientist in Translational Medicine Oncology to lead biomarker discovery and translational strategy across oncology pipelines... .... You will bridge discovery research and clinical development, guiding end-to-end PD and predictive biomarker...
- Noetik Inc. in South San Francisco is seeking a Senior Scientist to advance spatial biology and AI model development. You will execute and optimize spatial assays on human tissues, mentor junior staff, and collaborate across Histology, Scientific Operations, and Engineering...
$147.6k - $274k
...sciences are transforming drug discovery and development. Roche’s Research and Early Development... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...patients worldwide. Join the small-molecule team within AI for Drug Discovery (AI4...Full timeLocal areaWorldwideRelocation package$158.2k - $293.8k
...OpportunityThe PDQ Principal Quality Lead supports the Roche/Genentech Organization through the development and delivery of Quality... ...conclusions for entities (e.g. molecules in development, post approval... ...unprecedented problems, leading large/global cross-functional...Full timeLocal areaRelocation package- ...Job Description The Cell Line Development group in South San Francisco, CA is seeking a Scientist I to join a talented and... ...both platform and non-platform molecules, so the work varies considerably... ...based screening assays to rank large numbers of clones in 96-well and...Full timeTemporary workLocal area
$128.42k - $155.61k
...are seeking a highly motivated Scientist to expand high-throughput... ...scalable protein expression, purification, normalization, and characterization... ...reagents and therapeutic molecules. Operate, maintain,... ...safe laboratory operations. Lead or contribute to root-cause analysis...Hourly payFull timeSummer workLive inLocal areaRemote workFlexible hours- ...biopharmaceutical company focused on the discovery, development, and commercialization of targeted... .... Nurix Therapeutics is seeking a Scientist to lead bioanalytical strategies supporting... ...at the interface of small and large molecule bioanalysis, and will contribute to assay...
$159k - $207k
...medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision... ...countries, we are seeking a Principal Scientist to join our Large Molecule Analytical Development Team to serve as a Commercial Analytical Lifecycle...Contract workLocal area- Amgen in California is seeking a Senior Scientist - PKDM-BA to design and execute ADME-related experiments for large molecule therapies, supporting discovery and early development. The role emphasizes assay/technology development, mechanistic insights, and collaboration...
- Amgen in the United States seeks a Senior Scientist - PKDM-BA to design and execute biological and biophysical... ...experiments to understand ADME properties of large molecule therapeutics, supporting drug discovery and early development programs. The role is lab-based with emphasis...
- Genentech's Immunology Department is seeking a Scientist 3 to investigate novel mechanisms and... ...to treat inflammatory diseases. You will lead projects advancing immune regulation research and contribute to early clinical development. The role requires strong industry...Relocation package
$148k - $183k
...committed to the discovery, development, and commercialization of transformative... ...expertise in small-molecule drug discovery, structural... ...and reduce difficult purifications Rapidly gather reaction information... ...the role of Senior Research Scientist, Medicinal Chemistry is $148...Work at officeLocal areaWork from home1 day per week$92.6k - $172k
...Roche Group!As part of Pharma Technical Development (PTD) our organization is committed to... ...OpportunityThe Principal Associate Scientist ensures robust clinical and commercial... ...experienceExpertise in process development for large molecule parenteral Drug Product...Full timeLocal area$169.32k - $219.12k
...critical role in the discovery and development of life-changing scientific... ...and motivated Senior Scientist to join the Discovery Sciences... ...support target validation, lead identification, lead optimization... ...pharmacology of small and large molecules. This individual will...Full timeFor contractorsLocal area$173.1k - $321.5k
...we love.The Senior Principal Scientist serves as the scientific leader... ...that enable the successful development of cell therapy products. The... ...Bioanalytical Sciences project leads to developing integrated... ...manufacturing insights to support molecule progression, development...Full timeLocal areaRelocation package$100.4k - $186.4k
...and enable reverse translation to accelerate therapeutic development.The OpportunityAs a Scientist 3 in Translational Medicine OMNI, you will play a... ...or Python for analyzing, visualizing, and interpreting large-scale preclinical and clinical omics datasets.Independent...Full timeLocal areaRelocation package
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