Senior Associate Scientist

Position Summary Senior Associate Scientist – Discovery Biotherapeutics (Cambridge, MA). The role advances high‑throughput, automated mammalian antibody expression capability, integrating automation‑enabled platforms, software‑enabled workflows, and scalable discovery approaches. Key Responsibilities Operate and troubleshoot automation‑enabled platforms that accelerate antibody discovery and engineering. Perform discovery‑stage mammalian expression of antibodies and antibody‑derived formats (IgGs, fragments, multispecific biologics) in high‑throughput, plate‑based workflows. Develop and maintain high‑throughput, automated expression and purification workflows (4mL to 100mL scale) and perform QC analytics (A280, CE‑SDS, SDS‑PAGE, HT‑anSEC, endotoxin testing). Use liquid handling systems (e.g., Lynx 1800, Biomek i7) and participate in integrating liquid handling, incubators, culture handling, and downstream processing steps. Interface with laboratory software platforms (Benchling, Geneious Prime, Electronic notebook) to ensure traceable data generation compatible with computational and ML‑driven discovery. Collaborate with AI/ML, binder discovery, molecular interaction, and functional assay teams to support binder discovery campaigns. Participate in mid‑scale production and purification as needed. Qualifications & Experience B.S. with 4+ years of experience or M.S. with 2+ years of pharmaceutical R&D or related industry experience. Strong background in molecular biology (primer design, cloning, sequence analysis, HT‑PCR). Experience with high‑throughput and mid‑scale protein production and automated expression workflows. Hands‑on operation and control of AKTA chromatography workstations and liquid handling systems (Lynx 1800, Biomek i7). Knowledge of mammalian antibody expression systems (HEK293, CHO, CFE or equivalent). Strong interpersonal skills and ability to work independently while influencing cross‑functional teams. Excellent written and verbal communication skills; ability to work with urgency under tight deadlines. Experience with LIMS systems and Electronic Notebook is a plus. Compensation Overview Cambridge Crossing: $106,510 – $129,059 per year. Additional incentive cash and stock opportunities may be available based on eligibility. Compensation is ultimately determined by demonstrated experience and qualifications. Benefits Medical, pharmacy, dental, and vision coverage. Wellbeing support programs (BMS Well‑Being Account, Living Life Better, Employee Assistance Programs). 401(k) plan, disability insurance, life insurance, accident insurance, supplemental health insurance. Business travel protection, personal liability protection, identity theft benefit, legal support, survivor support. Paid time off: flexible time, unlimited sick leave (subject to approval), optional volunteer days, summer hours flexibility, leaves of absence, annual global shutdown. Additional benefits available based on location and eligibility. Equal Employment Opportunity Bristol Myers Squibb is an equal opportunity employer. We celebrate diversity and encourage applicants from all backgrounds to apply. #J-18808-Ljbffr Bristol-Myers Squibb