Lab Research Analyst I

Lab Research Analyst I

Work Arrangement: On-Site

Location: Durham, NC, US, 27710

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You. The Department of Surgery is looking for a Lab Research Analyst I. This role supports preclinical research by conducting animal studies, laboratory assays, specimen processing, and laboratory operations. The position requires hands-on experience with animal models, tissue collection, biochemical assays, data management, and collaboration with research staff.

Minimum Requirements: Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field. Work requires two years of research experience. A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE

Preferred Qualifications: Experience with small animal handling (rodents and preferably swine). Knowledge of tissue processing, protein analysis, and laboratory assays (ELISA, ELONA, coagulation assays, microscopy). Strong documentation, organizational, and record-keeping skills. Ability to work collaboratively in a research environment and train others. Familiarity with laboratory safety, animal research compliance, and inventory management.

Other Requirements: This position is onsite. The work is performed on-site or at a designated assignment location.

Be Bold. Animal Handling and Animal Modeling. Establish and maintain competency in handling and procedural skills for small animal models of traumatic injury (rodent and swine). Maintain required training, certification, and employee occupational health and safety requirements to allow animal handling and procedures. Interface with animal husbandry, veterinary, and other Department of Laboratory Animal Research (DLAR) staff to schedule and coordinate both care and experimentation with animals. Establish and maintain competency in tissue acquisition and processing protocols for typical experimentation: Microscopy with fixation and embedding; snap-freezing with homogenization for protein analysis. Assist with onboarding and training for other lab members working with animals and associated skills and assays.

Specimen Acquisition and Assay Performance. Review and update laboratory protocols for fixing, freezing, and storing plasma and tissue specimens from animal experiments. Perform assays with good record-keeping practices including data storage and archival in a shared digital laboratory notebook on plasma and tissue specimens: Enzyme-Linked Immunosorbent Assay (ELISA); optimize and perform both kits and assays de novo depending on the availability of commercial kits for target antigens (i.e., to single coagulation Factor proteins). ELONA (Enzyme-linked Oligonucleotide Assay); perform with commercially available oligonucleotides using laboratory protocol. Clot-based hemostatic assays; STAGO Start4 hemostasis analyzer provides consumer-oriented directions for partial thromboplastin time, prothrombin time, and single coagulation Factor-deficient assays. Microscopy; utilize immunostaining to localize coagulation enzymes in freshly fixed and frozen tissues from animal experiments at core microscopy facilities at Duke University. Assist with onboarding and training of other lab members who will utilize these assays and associated skills.

Organization, Administration, and Record-Keeping. Participate in bimonthly lab meetings (Fridays) by providing updates and feedback on the lab's ongoing projects. Participate in the lab's usual rotation schedule for cleaning and resupplying equipment, reagents, and glassware (typically one week of responsibility every other month). Assure digital laboratory notebook is up to date and compliant with laboratory standards. Assist with data organization and preliminary analysis, including preparation of data sets and experimental summaries for investigators in laboratory meetings. Monitor laboratory inventory and assist with ordering, organization, and management of laboratory supplies and reagents to ensure uninterrupted experimental operations. Perform other related laboratory duties incidental to the work described above.

Choose Duke. Join our award-winning team and be part of an inclusive culture that is committed to providing outstanding patient care, training tomorrow's leaders, and conducting innovative research. You'll also benefit from Duke's competitive benefits package, including health insurance plans, generous paid time off, retirement programs with employer contributions, tuition assistance for employees and their children, and more. Anticipated Pay Range: Duke University provides an annual base salary range for this position as USD $52,477.00 to USD $79,504.00. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate's work experience, education/training, and key skills; internal peer equity; as well as market and organizational considerations when extending an offer. Your total compensation goes beyond the dollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at: Equal Opportunity Employer: Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy- related conditions), sexual orientation, or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and reasonable accommodation(s) can be requested with Duke Access and Accommodations Services (email: View email address on click.appcast.io; phone: View phone number on click.appcast.io).