Clinical Project Manager - Oncology

Role Description

Clinical Project Manager - Oncology (Client Dedicated/Remote)

Are you passionate about advancing cancer research and bringing innovative therapies to patients worldwide? We are seeking experienced Clinical Project Managers with strong global oncology clinical trial experience to join a high-performing sponsor-dedicated team supporting a diverse portfolio of oncology studies across multiple indications and phases of development.

This is a fully remote, US-based opportunity where you will play a critical role in the operational leadership and execution of global clinical trials. We are specifically seeking professionals with 3+ years of hands-on Clinical Project Management experience leading global oncology studies and collaborating with cross-functional teams, vendors, and international stakeholders.

Job Responsibilities

• Support and partner with Clinical Study Leads and cross-functional study teams on global oncology trials
• Lead day-to-day study management activities across study startup, conduct, maintenance, and closeout
• Manage study timelines, deliverables, risks, and issue resolution
• Oversee external vendors, CROs, central laboratories, imaging vendors, and specialty providers
• Coordinate Clinical Trial Team (CTT) meetings and drive action item follow-up
• Support study-level planning, forecasting, and operational strategy execution
• Monitor study performance metrics and proactively identify areas requiring intervention
• Ensure inspection readiness and compliance with applicable regulations and sponsor requirements
• Collaborate with stakeholders across Clinical Operations, Data Management, Biostatistics, Medical Monitoring, Regulatory Affairs, Safety, Supply Chain, and Quality
• Contribute to study status reporting and executive-level communications
• Support achievement of study milestones, enrollment targets, database locks, and study closeout activities

Qualifications

• Bachelor's degree in a scientific, healthcare, or related field is required
• 3+ years of Clinical Project Management experience supporting global oncology clinical trials
• Experience managing studies across multiple countries and regions (North America, Europe, Asia-Pacific, Latin America, or other global regions)
• Vendor management experience required
• Strong understanding of clinical trial operations and study lifecycle management
• Experience supporting Phase I, Phase II, Phase III, and/or Phase IV oncology studies
• Strong working knowledge of ICH-GCP guidelines and clinical research regulations
• Proficiency with Microsoft Office Suite
• Ability to work effectively within global, cross-functional matrix organizations

Oncology Therapeutic Area Experience

• Lung cancer (NSCLC, SCLC)
• Melanoma
• Renal cell carcinoma (kidney)
• Bladder cancer
• Head & neck squamous cell carcinoma
• Triple-negative breast cancer
• Cervical cancer
• Gastric and gastroesophageal cancers
• Esophageal cancer
• Hepatocellular carcinoma (liver)
• Endometrial cancer
• Ovarian cancer
• Colorectal cancer
• Biliary tract cancer
• Prostate cancer
• Urothelial carcinoma
• Hematologic malignancies (multiple myeloma, lymphoma, leukemia)
• Antibody-drug conjugates (ADCs)
• Personalized cancer vaccines
• KRAS inhibitors
• T-cell engagers
• Cell-directed immunotherapies

Preferred Qualifications

• Experience independently leading global oncology studies
• Experience supporting complex, multi-regional Phase II and Phase III programs
• Experience with early-phase oncology studies (Phase I/Ib)
• Experience with immuno-oncology, targeted therapies, cell therapy, or hematologic malignancies
• Familiarity with CTMS, eTMF, IRT/RTSM, and clinical data review platforms
• Experience working in sponsor-dedicated or FSP environments

Key Skills & Competencies

• Strong project management and organizational skills
• Excellent communication and stakeholder management abilities
• Proven ability to manage multiple priorities in a fast-paced environment
• Strong risk identification and mitigation capabilities
• Detail-oriented with a focus on quality, compliance, and execution
• Strong collaboration skills across global teams and functions
• Ability to influence without direct authority and drive accountability across study teams

Clinical Phase Experience

• Phase I / First-in-Human Studies
• Phase I/Ib Dose Escalation Studies
• Phase II Proof-of-Concept Studies
• Phase II/III Registrational Studies
• Phase III Global Pivotal Trials
• Phase IV and Post-Marketing Studies

Benefits

• Company car or car allowance
• Health benefits including Medical, Dental, and Vision
• Company match 401k
• Eligibility to participate in Employee Stock Purchase Plan
• Eligibility to earn commissions/bonus based on company and individual performance
• Flexible paid time off (PTO) and sick time

Salary Range

$120,000-135,000