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Clinical Project Manager - Oncology

$120k - $135k
Full-time

Syneos Health Careers

Role Description

Clinical Project Manager - Oncology (Client Dedicated/Remote)

Are you passionate about advancing cancer research and bringing innovative therapies to patients worldwide? We are seeking experienced Clinical Project Managers with strong global oncology clinical trial experience to join a high-performing sponsor-dedicated team supporting a diverse portfolio of oncology studies across multiple indications and phases of development.

This is a fully remote, US-based opportunity where you will play a critical role in the operational leadership and execution of global clinical trials. We are specifically seeking professionals with 3+ years of hands-on Clinical Project Management experience leading global oncology studies and collaborating with cross-functional teams, vendors, and international stakeholders.

Job Responsibilities

  • Support and partner with Clinical Study Leads and cross-functional study teams on global oncology trials
  • Lead day-to-day study management activities across study startup, conduct, maintenance, and closeout
  • Manage study timelines, deliverables, risks, and issue resolution
  • Oversee external vendors, CROs, central laboratories, imaging vendors, and specialty providers
  • Coordinate Clinical Trial Team (CTT) meetings and drive action item follow-up
  • Support study-level planning, forecasting, and operational strategy execution
  • Monitor study performance metrics and proactively identify areas requiring intervention
  • Ensure inspection readiness and compliance with applicable regulations and sponsor requirements
  • Collaborate with stakeholders across Clinical Operations, Data Management, Biostatistics, Medical Monitoring, Regulatory Affairs, Safety, Supply Chain, and Quality
  • Contribute to study status reporting and executive-level communications
  • Support achievement of study milestones, enrollment targets, database locks, and study closeout activities

Qualifications

  • Bachelor's degree in a scientific, healthcare, or related field is required
  • 3+ years of Clinical Project Management experience supporting global oncology clinical trials
  • Experience managing studies across multiple countries and regions (North America, Europe, Asia-Pacific, Latin America, or other global regions)
  • Vendor management experience required
  • Strong understanding of clinical trial operations and study lifecycle management
  • Experience supporting Phase I, Phase II, Phase III, and/or Phase IV oncology studies
  • Strong working knowledge of ICH-GCP guidelines and clinical research regulations
  • Proficiency with Microsoft Office Suite
  • Ability to work effectively within global, cross-functional matrix organizations

Oncology Therapeutic Area Experience

  • Lung cancer (NSCLC, SCLC)
  • Melanoma
  • Renal cell carcinoma (kidney)
  • Bladder cancer
  • Head & neck squamous cell carcinoma
  • Triple-negative breast cancer
  • Cervical cancer
  • Gastric and gastroesophageal cancers
  • Esophageal cancer
  • Hepatocellular carcinoma (liver)
  • Endometrial cancer
  • Ovarian cancer
  • Colorectal cancer
  • Biliary tract cancer
  • Prostate cancer
  • Urothelial carcinoma
  • Hematologic malignancies (multiple myeloma, lymphoma, leukemia)
  • Antibody-drug conjugates (ADCs)
  • Personalized cancer vaccines
  • KRAS inhibitors
  • T-cell engagers
  • Cell-directed immunotherapies

Preferred Qualifications

  • Experience independently leading global oncology studies
  • Experience supporting complex, multi-regional Phase II and Phase III programs
  • Experience with early-phase oncology studies (Phase I/Ib)
  • Experience with immuno-oncology, targeted therapies, cell therapy, or hematologic malignancies
  • Familiarity with CTMS, eTMF, IRT/RTSM, and clinical data review platforms
  • Experience working in sponsor-dedicated or FSP environments

Key Skills & Competencies

  • Strong project management and organizational skills
  • Excellent communication and stakeholder management abilities
  • Proven ability to manage multiple priorities in a fast-paced environment
  • Strong risk identification and mitigation capabilities
  • Detail-oriented with a focus on quality, compliance, and execution
  • Strong collaboration skills across global teams and functions
  • Ability to influence without direct authority and drive accountability across study teams

Clinical Phase Experience

  • Phase I / First-in-Human Studies
  • Phase I/Ib Dose Escalation Studies
  • Phase II Proof-of-Concept Studies
  • Phase II/III Registrational Studies
  • Phase III Global Pivotal Trials
  • Phase IV and Post-Marketing Studies

Benefits

  • Company car or car allowance
  • Health benefits including Medical, Dental, and Vision
  • Company match 401k
  • Eligibility to participate in Employee Stock Purchase Plan
  • Eligibility to earn commissions/bonus based on company and individual performance
  • Flexible paid time off (PTO) and sick time

Salary Range

$120,000-135,000

Vacancy posted 1 day ago
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