Senior Director, Digital & Technology, Portfolio & Financial Management

Regeneron is a leading biotechnology company built on a simple but powerful mission: to use the power of science to bring new medicines to patients, over and over again. Founded and led by physician-scientists, we've turned that mission into one of the industry's most productive pipelines, nearly all of it homegrown in our own laboratories, powered by proprietary technologies like our VelociSuite® platform. From Dupixent and EYLEA to a rapidly expanding portfolio across oncology, cardiovascular and metabolic disease, neuroscience, and rare disease, our science is reaching millions of patients worldwide, and we're just getting started.

As we invest billions in new manufacturing capacity, expand our global footprint, and build the next generation of digital and technology capabilities to match the scale of our ambition, Regeneron offers a rare combination: the resources and reach of an industry leader, paired with the energy, curiosity, and relentless focus on invention of a company still writing its next chapter. This is a place where technology doesn't just support the business, it accelerates the science that changes patients' lives.

This role will sit on-site in our Sleepy Hollow, NY office a minimum of 4 days/week.

Role Description

Regeneron is seeking a Senior Director to lead technology portfolio management, IT financial management, and business management for its Commercial and G&A Digital & Technology organization during a period of significant transformation, including Oracle Fusion implementation and enterprise AI adoption. This leader will establish the strategy, governance, and operating model for portfolio and financial management while driving investment prioritization, value realization, and organizational effectiveness across the technology portfolio. The role also serves as Chief of Staff to the SVP of Commercial and G&A Digital & Technology, acting as a trusted advisor responsible for leadership planning, communications, and execution of key strategic initiatives. Working closely with senior technology, finance, and business leaders, this individual will influence major investment decisions and help ensure technology investments deliver measurable business outcomes.

What You'll Lead

• Lead enterprise technology portfolio management across Commercial and G&A D&T, overseeing intake, prioritization, planning, and investment sequencing based on business value, risk, and delivery capacity.
• Own IT financial management, including budgeting, forecasting, cost transparency, chargeback/allocation models, and technology investment value realization.
• Lead value realization across the Digital & Technology portfolio by developing business cases, defining success metrics, and tracking, monitoring, and reporting realized business value against investment objectives.
• Establish and govern enterprise portfolio and financial management standards, including intake processes, stage-gate reviews, investment frameworks, and governance forums.
• Direct annual and ongoing technology planning cycles, aligning budgets, resource capacity, and prioritization with enterprise strategy and performance objectives.
• Build and mature Technology Business Management (TBM) capabilities, leveraging cost and performance data to improve executive decision-making and demonstrate technology value.
• Lead and develop a high-performing team while driving improvements in portfolio predictability, forecast accuracy, resource utilization, cost visibility, and executive reporting.
• Serve as Chief of Staff to the SVP, managing leadership operating rhythms, strategic initiatives, executive communications, stakeholder engagement preparation, standardized executive reporting, AI-enabled portfolio management initiatives, and key vendor relationships.

What You Bring

• BS/BA in Information Systems, Finance, Business, or a related field required; MS or MBA preferred.
• 15+ years of progressive leadership across technology portfolio management, PMO, or IT financial management, ideally within a complex, matrixed enterprise.
• Strong command of portfolio and financial management disciplines (platform-agnostic, e.g., PPM/SPM, technology business management, and stage-gate governance frameworks).
• Experience designing and facilitating executive governance forums, such as steering committees and investment review boards, and driving decisions among senior stakeholders.
• Experience partnering directly with a senior executive in a chief-of-staff, business-management, or executive-office capacity, including executive communications and board-level preparation, is strongly preferred.
• Comfort operating with a high degree of autonomy and discretion, exercising sound judgment on behalf of senior leadership. Proven ability to influence senior leaders, drive accountability across functional areas, and attract top talent.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$216,100.00 - $360,200.00