Vice President, Regulatory Science

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi‑selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C‑selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D‑selective inhibitor; and RMC-5127, a RAS(ON) G12V‑selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity The Vice President will be the head of Regulatory Science at Revolution Medicines and will report to head of Regulatory and Quality. The position is responsible for expanding and leading a high functioning group that provides clinically focused global regulatory strategy. Provide ethical and mission‑driven leadership of the Regulatory Science function. Embody and practice the company’s mission‑driven culture. Ensure that our core values guide our strategic vision and our day‑to‑day decision making. Provide a vision for the Regulatory Science organization and develop a plan to achieve it. Design and rapidly scale a function that meets the needs of an explosive pipeline in areas of high unmet medical need and intense industry competition. Ensure high‑quality, well‑vetted, globally relevant regulatory research, strategies and advice are provided to project teams, working groups, and management via Global Regulatory Leads. Influence decision‑making of senior leadership Collaborate closely and form effective relationships with other functional heads to ensure high quality, cross‑functionally sound decision‑making. Collaborate with peer leaders and management to ensure regulatory considerations are integrated upstream appropriately, e.g., target product profiles, clinical development plans, financial planning. Ensure consistency in approach (one playbook) and that learning occurs across staff. Continue to build the Regulatory Science organization, strategizing with other leaders to maximize enterprise‑wide impact. Actively lead the function and support team member career development. Required Skills, Experience and Education Local to San Francisco Bay Area or able to travel to headquarters frequently and for adequate durations (up to 25%). BA/BS degree in life sciences or related disciplines. At least 15 years of experience in drug development regulatory affairs. Minimum of 10 years of experience in regulatory leadership or executive role. Significant oncology experience. Expertise in navigating global regulatory environments in a commercial setting. Ability to successfully work in a fast‑paced, demanding and highly cross‑functional environment. Experience scaling an organization rapidly. Clearly understands the role of regulatory science in drug development and global commercialization, and is comfortable with ambiguity, risk, and optimizing for business needs. Preferred Skills Advanced degree in life sciences enabling technical fluency in oncology. Prior senior regulatory executive in oncology drug development at a medium or large pharmaceutical enterprise but who also understands the startup environment. Base Pay Salary Range $284,000—$355,000 USD Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. #J-18808-Ljbffr