Senior Medical Director, Clinical Development Rare Cardiology

The Senior Medical Director Clinical Development will lead the clinical team for a high‑visibility program and report to the Global Clinical Head. This role offers an excellent opportunity for an experienced and motivated drug developer to advance an innovative, late‑stage study. Responsibilities Lead cross‑functional clinical program teams to deliver high‑quality studies and research strategies, ensuring scientific rigor and optimal benefit–risk management. Serve as the clinical authority for assigned programs, overseeing study design, execution, data interpretation, and regulatory deliverables in compliance with GCP. Provide strategic medical and scientific input across R&D, translational science, commercial, and business development activities, including due diligence and collaborations. Mentor and develop Medical Directors, Clinical Development Scientists, and fellows to build organizational scientific and leadership capability. Represent the program internally and externally through governance presentations, regulatory interactions, scientific publications, and engagement with key opinion leaders. Required Qualifications MD with specialty training in Internal Medicine. 7+ years of experience in clinical development, clinical research, global regulatory, and product development. Has prepared documents and attended regulatory meetings with FDA and other regulatory agencies. Experience designing and executing multinational clinical trials. Demonstrated ability to lead cross‑functional teams to define clinical strategy and study design. Experience supporting business development activities. Ability to learn rapidly, think critically, and operate effectively in a fast‑paced environment. Ability to work in an office environment, use a computer, engage in communications, and collaborate with others during standard business hours. Preferred Qualifications Board certification. Experience in ATTR amyloidosis. Advanced knowledge of the assigned therapy area. PhD in related discipline. Experience with BLA/MAA submissions. Demonstrated experience as a clinical trialist with a strong external network. Experience operating at the clinical‑commercial interface and shaping clinical strategies with commercial insight. Broad awareness of the global therapeutic landscape and regulatory environment within rare or cardiometabolic diseases. Willingness and ability to travel nationally and internationally. Compensation Annual base pay range: USD $280,895.20 to $421,342.80. Eligibility for short‑term incentive bonuses, equity‑based awards for salaried roles, and commissions for sales roles. Benefits include qualified retirement programs, paid time off, and health, dental, and vision coverage. Equal Opportunity Our organization is a designated Equal Employment Opportunity and affirmative action employer. We do not make decisions about employment, training, compensation, promotion, or other terms and conditions of employment based on race, color, religion, creed, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy or related medical conditions, parental status, military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness, or other characteristics protected by law. We comply with all applicable laws and regulations on non‑discrimination in employment and work authorization. #J-18808-Ljbffr AstraZeneca