Senior Network Systems Architect

Be a hero for our rare disease patients

Why Join Us?

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life‑changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Position Summary

We are seeking a seasoned Senior Network Systems Architect to lead the evolution of our global hybrid network and systems infrastructure. This role requires a strong foundation in Cisco Meraki, Azure Cloud networking, and Cisco ASA. The ideal candidate will bring hands‑on expertise in designing, scaling, and supporting both on‑premises and cloud environments, while contributing to a secure, reliable, and high‑performing enterprise network. Familiarity with automation tools such as Python, Terraform, and Ansible is preferred, but not mandatory for success. Experience working with Managed Service Providers (MSPs) and global telecom carriers to negotiate contracts and provision circuits is essential. This position combines architecture with day‑to‑day operational support, requiring a balance of strategic planning and practical execution.

Work Model

Flex: This role will typically require onsite work 2-3 days each week or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite.

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Responsibilities

• Manage day to day operations, Architect, deploy, and manage hybrid infrastructure environments using Cisco Meraki, Azure networking services, and Cisco ASA firewalls
• Design and templatize scalable Meraki configurations and maintain consistent deployment practices across locations
• Create and maintain Hub-and-Spoke network architectures across Azure regions, ensuring resiliency, segmentation, and traffic control
• Provide a solid understanding of routing protocols, Azure routing, UDRs, NAT gateways, VPN/ExpressRoute gateways, and NVA-based architectures with multi‑region failover support
• Develop and maintain architectural documentation including high‑level designs, topology diagrams, and operational procedures
• Support operational excellence by serving as an escalation point for L1/L2/L3 network and systems issues and ensuring timely resolution
• Perform deep packet inspection and network troubleshooting using tools like Wireshark and NetFlow
• Participate in the planning, procurement, and provisioning of global circuits, including direct engagement and negotiation with carriers and service providers
• Collaborate with MSPs and internal teams to manage operations, incidents, capacity planning, and global deployments
• Familiar with automation tools such as Python, Terraform, and Ansible to streamline network and systems workflows
• Utilize tools like ThousandEyes, Azure Monitor, and log analytics to ensure observability and proactive incident response
• Ensure strong cross‑functional collaboration with IT security, infrastructure, and compliance teams
• Support growth and scaling initiatives by addressing evolving infrastructure needs, integrating new locations, and expanding global connectivity
• Contribute to the recruitment, mentorship, and development of junior and mid‑level engineers

Requirements

• 7+ years of experience in network and systems architecture, with a blend of cloud and on‑premises responsibilities
• Strong hands‑on experience with Cisco Meraki, Cisco ASA, and Azure Firewall, as well as Azure network design and deployment
• Solid understanding of core networking concepts such as BGP, IPsec, and high‑availability configurations
• Demonstrated experience managing or collaborating with MSPs and supporting global operations
• Experience negotiating with and provisioning circuits through global telecom carriers
• Strong analytical and troubleshooting skills, especially in production environments
• Comfortable handling operational demands, including incident response, change control, capacity planning, and documentation
• Excellent communication and interpersonal skills, with experience engaging both technical teams and senior stakeholders
• Ability to manage shifting priorities and infrastructure needs as the company grows and scales globally

Preferred Qualifications

• Bachelor’s degree in computer science, Engineering, or a related field, or equivalent work experience
• Prior experience working in pharmaceutical or regulated industries
• Working knowledge of Windows Server, Active Directory, DNS, DHCP, and group policy configurations and core systems operations
• Experience with zero‑trust network design, hybrid cloud security models, and compliance frameworks
• Certifications such as CCNP, Azure Network Engineer Associate, or equivalent

Pay Range: $161,200 USD - $199,200 USD

Benefits

• Generous vacation time and public holidays observed by the company
• Volunteer days
• Long‑term incentive and Employee stock purchase plans or equivalent offerings
• Employee wellbeing benefits
• Fitness reimbursement
• Tuition sponsoring
• Professional development plans
• Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at View email address on click.appcast.io.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.