Scientist I (R&D)

Company: Pharmaceutical Company Role: Scientist I R&D Location: Onsite in Cambridge, MA Contract: 1 year W2 Contract Hourly rate: 51/hour Start date: 1/4/2027 Benefits: Medical, Dental, and Vision An onsite opportunity is available in Cambridge, MA for a temporary Scientist to support discovery-stage research within an ALS-focused neurology team. This 12-month assignment will contribute to early research efforts centered on target identification and validation, with a focus on the molecular and cellular mechanisms underlying ALS and related neurodegenerative diseases. In this role, you will design, execute, and analyze experiments investigating genomic and proteomic changes in ALS-relevant pathways. Responsibilities include performing molecular biology assays such as qPCR, ddPCR, gel electrophoresis, and western blotting to assess gene and protein expression. You will also support proteomic studies using immunoprecipitation and protein quantification platforms including HTRF, AlphaLISA, and MSD. Additional responsibilities include routine mammalian cell culture, plasmid transfection, viral transduction, and work with human iPSC-derived neurons and established cell lines. You will contribute to target validation studies through immunostaining, fluorescence microscopy, quantitative image analysis, and co-localization, morphological, and phenotypic assessments. The role also involves assay development, optimization, and validation, along with preparation of data summaries, figures, and internal scientific presentations. The ideal candidate has a strong background in molecular and cellular biology, with hands-on experience in genomics- and proteomics-based assays. A PhD or MS in molecular biology, biochemistry, neuroscience, or a related discipline is preferred. Success in this role requires strong analytical and problem-solving skills, scientific rigor, careful documentation, and the ability to work both independently and collaboratively while maintaining high standards for safety, quality, and data integrity. Must-Have Skills: qPCR, ddPCR, western blotting, mammalian cell culture, immunostaining, fluorescence microscopy, image analysis, iPSC-derived neurons Nice-to-Have Skills: gel electrophoresis, immunoprecipitation, HTRF, AlphaLISA, MSD, plasmid transfection, viral transduction, genomics, proteomics, assay development, assay optimization, target validation EOE Statement: Specialist Staffing Group is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status. In addition to base pay, employees may be eligible for benefits such as health insurance, health savings accounts, retirement savings plans, life and disability insurance, and paid leave where required by applicable law. Eligibility may vary based on factors such as location and hire date and is subject to change. #J-18808-Ljbffr Real Staffing