Principal Scientist, High-Content Imaging
Johnson & Johnson Innovative Medicine
Role Principal Scientist in High-Content Imaging within Johnson & Johnson's Innovative Medicine division, focusing on advancing therapeutic discovery in Immunology, Neuroscience, and Oncology. Responsibilities include developing, validating, and deploying complex high-content imaging assays across diverse cell models and tissues, establishing workflows, troubleshooting, and optimizing protocols. The role involves collaborating with internal teams, CROs, and external partners to generate high-quality data, support data analysis pipelines, and translate imaging readouts into biological insights. Qualifications Ph.D. in Biochemistry, Systems Biology, or related field; minimum of 4 years industry experience with proven expertise in high-content imaging, assay development, and computational image analysis; excellent communication and collaborative skills. Preferred Experience with complex cell/tissue models, external collaborations, data integration, and programming in R/Python; familiarity with AI/ML approaches is a plus. High-value specifics include application across disease-relevant models in Immunology, Neuroscience, and Oncology, with a focus on drug discovery workflows. The position is based in Spring House, PA, with an emphasis on technical leadership and innovation in high-dimensional biological assays. #J-18808-Ljbffr Johnson & Johnson Innovative Medicine
$173.2k - $272.6k
Job DescriptionJob Description Summary: Principal Scientist/Director, Biologics Drug Substance... ...position oversees a team of scientists, leads high-impact process development, and manages... ...authoring regulatory submission content (e.g., BLA sections) and/or working with...PrincipalContentFull timeContract workFor contractorsLocal areaFlexible hours$231.9k - $365k
...is seeking an experienced anatomic pathologist to join a highly collaborative team of scientists (12 anatomic pathologists, 3 clinical pathologists, and... ...microscopyImmunohistochemistry and in situ hybridizationQuantitative digital image analysis and targeted machine learning...PrincipalFull timeFor contractorsLocal area$255.8k - $402.7k
...exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in... ...peripheral system. We are seeking a highly qualified individual for a position... ..., including blood/tissue sampling, imaging, electrophysiological, wearable devices...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours$117k - $201.25k
...Johnson & Johnson Innovative Medicine R&D is recruiting for a Principal Scientist, CMC Regulatory Affairs - Combination Products. This... ...Review device and combination product‑specific submission content for clinical trial applications, marketing applications, Notified...PrincipalContentLocal areaImmediate start$255.8k - $402.7k
...exciting opportunity for a physician-scientist to join our group as a- Principal Scientist (Clinical Director) in... ...peripheral system. We are seeking a highly qualified individual for a position... ..., including blood/tissue sampling, imaging, electrophysiological, wearable devices...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$255.8k - $402.7k
...exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in... ...peripheral system. We are seeking a highly qualified individual for a position... ..., including blood/tissue sampling, imaging, electrophysiological, wearable devices...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$117k - $201.25k
...& Johnson company, is recruiting for a Principal Scientist, R&D Data, Data Science & Artificial Intelligence... ...teams to define, evaluate, and execute high-impact data science, digital health, AI... .... Develop a deep understanding of imaging, digital health, clinical, and real-...PrincipalTemporary workLocal areaRemote work$92k - $111k
...recruiting for a Postdoctoral Scientist - Multimodal Representation... ...areas. We are looking for a highly motivated and innovative Postdoctoral... ...in deep learning for imaging microscopy and multi-omics. The... ...biological data (e.g., high-content imaging, phenomics, transcriptomics...ContentTemporary workFixed term contractLocal areaRemote work$190.8k - $300.3k
...scientific concepts into sound development strategies.Deliver high-quality nonclinical strategies, risk assessments, and regulatory... ...Coordinators, Discovery Preclinical Leaders, Compound Leaders, and scientists across NDS and/or Preclinical Development, while ensuring...PrincipalFull timeFor contractorsLocal areaFlexible hours$173.2k - $272.6k
...Pennsylvania, is seeking a dynamic and collaborative scientist for the Drug Metabolism and Pharmacokinetics (DMPK) group. The Principal Scientist will be a key contributor to multi-... ...will be to work within teams of highly collaborative, cross-functional scientists to...PrincipalFull timeFor contractorsLocal areaFlexible hours$190.8k - $300.3k
Job DescriptionDescriptionThe Senior Director (Sr. Principal Scientist), Regulatory Affairs Liaison reports to the Executive Director or Associate... ...programs. The individual functions with a strategic focus, a high degree of independence and provides regulatory oversight for...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours$173.2k - $272.6k
...treatment of diseases in people and animals.We are seeking a Principal Scientist to join our Analytical Commercialization Technology (ACT)... ...Point, PA sites. This is an exciting opportunity to lead a highly collaborative team of scientists utilizing innovative analytical...PrincipalFull timeFor contractorsLocal areaFlexible hours$142.4k - $224.1k
Job DescriptionWe are seeking an Associate Principal Scientist to join our Separations Sciences team, within the Analytical Enabling Capabilities... ...in the Separations Sciences team, you will work within a highly collaborative team to enable the advancement of the...PrincipalFull timeFor contractorsLocal areaFlexible hours- ...Principal Scientist position in biologics optimization at Johnson & Johnson's Spring House, PA facility. Leads integration of experimental data... ...platforms Experience with yeast display, NGS, high-throughput screening, or related discovery technologies Demonstrated...Principal
$137k - $235.75k
...every step of the way. Learn more at Purpose: The Senior Principal Scientist will be a key member of discovery project teams and interact... ...and simulation, supported by peer-reviewed publications is highly desired. Excellent interpersonal, organizational, oral/written...PrincipalLocal area- Johnson & Johnson Biologics Discovery in Spring House, PA seeks a Principal Scientist, Protein Purification, Team Lead to guide a team delivering... ...to align strategy with program goals while building an inclusive, high-performance culture. #J-18808-Ljbffr Johnson JohnsonPrincipal
- ...Merck seeks a physician-scientist to lead translational medicine and early clinical development for neuroscience therapeutics. The role... ...biomarker validation strategies incorporating blood/tissue sampling, imaging, electrophysiology, and wearable devices Support regulatory...Principal
- ...way. Learn more at are searching for the best talent for Principal Scientist Protein Purification Team Lead in Spring House PA. Purpose... ...developing scientists and creating an inclusive collaborative high-accountability team. A drug-discovery orientation including...PrincipalFull timeLocal area
- Job Description Description The Senior Director (Sr. Principal Scientist), Regulatory Affairs Liaison reports to the Executive Director or Associate... ...programs. The individual functions with a strategic focus, a high degree of independence and provides regulatory oversight for...PrincipalLocal areaWorldwide
$55k - $64k
...Engagement. Visit NMSLabs.co. Job Summary We are seeking an R&D scientist with deep expertise in LC‑MS/MS method development for the... ...matrices. Lead and/or manage projects, ensuring timely delivery of high‑quality results. Mentor junior team members, fostering a...PrincipalFull timeWork at officeMonday to FridayShift workDay shift- ...talent for a PharmD Fellow Safety Analysis Scientist to be located in Horsham PA. About... ...as required. The Fellow will gain a high-level understanding of case processing safety... ...members be able to link discussions to content and deliver quality results with guidance...ContentFull timeLocal area
$142.4k - $224.1k
...Associate Principal Scientist supporting vaccine and infectious disease products within a regulatory affairs team. The role involves developing... ...Experience in anti-infectives and/or vaccine development highly preferred Compensation: $142,400–$224,100 base...Principal- Role Principal Scientist and Team Lead in Protein Purification within Johnson & Johnson's Biologics Discovery, focusing on advancing therapeutic... ...or complex protein formats early-stage CMC development high-throughput automation and external scientific contributions Location...Principal
- ...tomorrow.Section 1: Position SummaryThe Principal Security Ops Analyst will be responsible... ...Endpoint ProtectionCASBUBADLPWeb Proxy/Web content filteringVulnerability managementFile... ...professionally) with all levels within Ascensus.Highly organized and able to process and manage...PrincipalContentFull timeWork experience placementSecond jobRemote work
- ...Principal Scientist position leading immunology biomarker strategy across clinical development programs. The role combines scientific expertise... ...development decisions Demonstrated ability to lead highly matrixed teams and influence cross-functional stakeholders...Principal
$190.8k - $300.3k
Job DescriptionWe are seeking an accomplished and highly motivated Principal Scientist (Director) to serve as an Immunology Biomarker Lead within Translational Clinical Biomarkers. This role provides strategic and scientific leadership in the design, execution, analysis...PrincipalFull timeFor contractorsLocal areaFlexible hours$190.8k - $300.3k
...company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-... ...design meetings to ensure that the data evaluated are in high quality and satisfy analysis requirements. May lead a team of statisticians...PrincipalContract workWork experience placementLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$117k - $201.25k
...at Johnson & Johnson Innovative Medicine is recruiting for a Principal Scientist, AI & Autonomous Discovery Systems, to advance AI-powered... ...increase experimental throughput, reduce cycle times, and advance high-value therapeutic programs. The primary location for this...PrincipalTemporary workLocal areaRemote work$142.4k - $224.1k
...marketing applications and lifecycle management. The Early Clinical Scientist (ECS) provides operational and scientific leadership for the... ...requirements, supporting study objectives and the delivery of high-quality data. Ensures appropriate clinical safety assessment...PrincipalFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$260.3k - $409.7k
...focused on Cardiovascular Disease and related conditions. The Principal Scientist (Clinical Director) must have a strong background in basic... ...platforms utilizing established and novel biomarkers, including imaging, electrophysiological and behavioral responses to...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work
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