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Drug Discovery Scientist (Remote | $60-$90/hr)

$60 - $90 per hour

Synthires

West Virginia
  • Remote job

Job Description

Drug Discovery Scientist

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Position: Drug Discovery Scientist

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Type: Hourly Contract

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Compensation: $60–$90/hour

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Location: Remote

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About the Opportunity

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This opportunity is for experienced Drug Discovery Scientists to contribute to an advanced AI research and evaluation project focused on pharmaceutical research and development.

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You'll apply your scientific expertise to design realistic, evidence-driven drug discovery problems that require AI models to reason through incomplete, indirect, and potentially misleading scientific evidence . You'll create research prompts, build supporting data rooms using real source-grounded information, develop rigorous grading frameworks, and validate the resulting tasks.

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The role is ideal for experts who can distinguish genuine scientific reasoning from pattern matching and confidently evaluate the quality of complex research conclusions.

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Responsibilities

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  • Design challenging, realistic drug discovery research problems based on authentic scientific workflows.
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  • Develop research scenarios where the correct conclusion must be derived from multiple pieces of evidence rather than directly stated.
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  • Build comprehensive data rooms using real, source-grounded scientific data and documentation.
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  • Ensure every decisive scientific value and piece of evidence can be traced back to a reliable source.
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  • Create detailed grading documents and evaluation rubrics that assess scientific reasoning and substantive conclusions.
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  • Evaluate AI-generated research outputs for scientific accuracy, logical consistency, and defensibility .
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  • Run verification and calibration processes to ensure tasks are reproducible, appropriately difficult, and objectively scorable.
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  • Identify weaknesses in task design, evidence, or evaluation criteria and revise them accordingly.
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  • Provide expert judgment on scientific questions, task difficulty, and the quality of AI reasoning.
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  • Collaborate with project reviewers and other domain experts to refine research tasks.
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Required Qualifications

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  • Professional expertise in one or more of the following areas:
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  • Mechanistic enzymology
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  • Structure-guided peptide design
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  • Structure-guided antibody design
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  • Fragment-based drug discovery
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  • Structure-based medicinal chemistry
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  • PhD or equivalent industry experience in drug discovery, medicinal chemistry, chemical biology, biochemistry, or a closely related field.
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  • Strong understanding of drug discovery research methodologies and scientific evidence evaluation .
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  • Ability to construct complex scientific problems with defensible conclusions.
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  • Strong analytical and critical-thinking skills.
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  • Ability to evaluate scientific reasoning quality , not simply final answers.
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  • Strong scientific writing and documentation skills.
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  • Comfortable working independently in a remote research environment .
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  • Ability to commit at least 20 hours per week .
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Preferred Qualifications

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  • Experience designing or evaluating drug discovery research strategies .
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  • Strong background in structure-based drug design, protein–ligand interactions, enzymology, or molecular discovery.
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  • Experience working with scientific literature, experimental datasets, structural data, and research documentation .
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  • Experience developing research assessments, scientific benchmarks, or evaluation frameworks .
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  • Familiarity with open-source scientific tooling and computational research workflows.
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  • Experience evaluating AI-generated scientific research or technical outputs is a plus.
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  • Strong ability to distinguish defensible scientific conclusions from unsupported assumptions or superficial reasoning .
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Compensation

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  • Competitive compensation of $60–$90/hour.
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  • Hourly contract engagement.
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  • Fully remote.
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  • Minimum commitment: 20 hours/week.
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  • Up to 40 hours/week available.
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  • Claude Max subscription required for the project and fully reimbursed .
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  • Work conducted through a browser-based research studio and Claude Code .
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Application Process

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  1. Apply to the role
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  3. Complete the required screening questions
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  5. Provide details about your drug discovery and scientific research experience
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  7. Complete the relevant scientific assessment
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  9. Participate in the evaluation/interview stage
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  11. Complete onboarding and tooling setup
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  13. Begin designing and evaluating drug discovery research tasks
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Vacancy posted 3 days ago
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