Postdoctoral Research Associate - Structural Biology - Sun lab

Jobs in Structural Biology and Related Fields Postdoctoral Research Associate - Structural Biology - Sun lab St. Jude Children's Research Hospital, Tennessee , United States The Sun lab are seeking a highly motivated and creative postdoctoral fellow to join their group in the Department of Structural Biology at St. Jude Children’s Research Hospital. The project focuses on structure-based drug discovery projects in the lab. This is an exceptional opportunity to work at the forefront of structural biology and drug discovery in a highly collaborative, well-resourced environment with access to state-of-the-art cryo-EM facilities. The role: Independently design, execute, troubleshoot, and interpret experiments in structural biology, biochemistry, and cell biology Perform protein complex expression/purification (mammalian and insect systems), cryo-EM sample preparation, data collection, and high-resolution structure determination to understand the working mechanism of small molecules Conduct functional assays in mammalian cells and animal models to study pharmacology of novel small molecules Rapidly learn and integrate new techniques as the project evolves Maintain detailed records, analyze data, prepare manuscripts, and present results at lab meetings and scientific conferences Work collaboratively with team members and external collaborators while taking ownership of sub-projects Ph.D. in biochemistry, structural biology, biophysics, cell biology, pharmacology, chemical biology or a closely related field Demonstrated ability to work independently and as part of a team Strong publication record with at least one first-author paper in a peer-reviewed journal Preferred Qualifications: Prior hands-on experience with single-particle cryo-EM (sample prep, data processing, model building) is a plus Background in chemical biology will be a plus Excellent written and oral communication skills Enthusiasm for mentoring junior lab members and contributing to a positive, supportive lab culture #J-18808-Ljbffr St. Jude Children's Research Hospital, Tennessee , United States