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Postdoctoral Scientist Immunosafety/Toxicology

$58k - $123.2k

Initial Therapeutics, Inc.

Post-Doctoral Scientist – Fixed Duration Employment – Investigative Toxicology (Immune-Mediated Drug-Induced Liver Injury) Are you looking to make a significant difference by helping to solve one of the most consequential unsolved problems in drug safety? We are seeking an ambitious post-doctoral scientist with strong research and communication skills to contribute to a high-visibility research program focused on predicting immune-mediated liver injury before it ever reaches patients. Responsibilities Investigate how interactions between liver biology and the immune system contribute to drug-induced liver injury, working across hepatocyte biology, innate immune sensing, and adaptive immunity. Help build and apply human-relevant model systems that integrate liver and immune biology into a mechanistically informed, predictive safety platform. Contribute to a platform capable of identifying immune-mediated liver liabilities earlier in drug development, with the potential to change how the industry approaches this challenge. Work within a collaborative, academic-style postdoctoral group that leads NAMs innovation at Lilly, with close connections across drug metabolism, computational toxicology, translational medicine, and immunogenicity functions. Identify areas of key need across drug development and champion creative solutions to address those needs, maintaining external awareness and learning to benefit the organization. Present findings at conferences and publish in high quality peer-reviewed journals. Basic Qualifications PhD in immunology, toxicology, cell biology, pharmacology, biochemistry, or a closely related life science field (degree conferred or expected before the start date). Strong foundation in immunology, cell biology, or mechanistic toxicology. Demonstrated ability to design experiments, learn new approaches, and solve problems independently. Track record of peer-reviewed publications in toxicology, immunology, or liver biology, with preference for work directly relevant to DILI or immune-mediated organ toxicity. Additional Information Position location: Indianapolis, Indiana. This position is not permanent. It is for a fixed duration of two years with potential to extend to three years and for a maximum of up to four years. You will have opportunities to apply for full-time positions after your duration is complete. Additional Skills/Preferences Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals. Excellent communicator (oral and written) with presentation experience, and a strong publication record. Proficient in data analysis and reporting. Experience with primary mammalian cell culture and in vitro model systems. Interest or background in liver biology, immune cell biology, antigen presentation, or drug metabolism. Familiarity with complex cell models, co-culture systems, or organ-on-chip approaches is a plus. Strong interpersonal skills and a track record of success in collaborative, multidisciplinary team environments. Program Benefits Top industry research experience Mentoring by some of Lilly’s top scientists Laboratory and classroom training and education to further your development Collaboration and networking across dozens of postdoctoral scientists and other researchers Compensation and Benefits $58,000 - $123,200 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. EEO Statement Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. We offer accommodations for individuals with disabilities as part of the application process. If you require accommodation, please complete the accommodation request form at for further assistance. #J-18808-Ljbffr Initial Therapeutics, Inc.

Vacancy posted 1 day ago
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