Senior Director, Global Program Development Lead - DMD/Neuromuscular

Overview Who we are REGENXBIO is an exceptional place to work. You'll have the opportunity to collaborate with some of the best and the brightest people, touch amazing science, and be a part of extraordinary plans. Our core values: Trust, Accountability, Perseverance, and Innovation drive everything we do. We aim to bring these values to life every day with all that we do, and we believe that what we do matters - to patients, to their families, and to their communities. The opportunity As a Senior Director, Global Program Development Lead (PDL), you will be in a highly visible leadership role that sits at the center of the cross-functional program team, to shape a compelling strategic direction, set ambitious priorities, and drive disciplined execution, in partnership with senior leadership. Leveraging deep expertise in drug development and commercialization, along with a forward-looking perspective and strong operational mindset, you will ensure the program team operates with clarity, rigor, and urgency while fostering collaboration and high performance. Accountable for cross-functional outputs, you\u2019ll guide the program’s path forward by anticipating opportunities, mitigating risks, cultivating strategic options, and driving decision-making amid complexity and uncertainty to achieve long-term program success. What you'll be doing Lead overall program strategy, accountable for an integrated Program Development Strategy, Target Product Profile (TPP), and lifecycle management plan aligned with corporate objectives and long-term portfolio goals to maximize asset value. Drive cross-functional strategic integration, ensuring scientific rigor and emerging clinical data, competitive intelligence, and evolving market dynamics inform program direction and critical decisions. Identify key development challenges and define strategic options across functions, including timelines, budgets, risks, and trade-offs, enabling timely, high-quality decision-making. Support business development activities, including opportunity assessment and due diligence; represent the program on Joint Steering Committees for partnered assets. Maintain external perspective and scientific credibility through engagement with KOLs, patient advocacy groups, and other external experts. Evolving and maturing the program’s external communications strategy in partnership with key groups, including the elements of scientific messaging, competitive positioning, and stakeholder alignment. Drive cross-functional program execution within a matrix organization, ensuring high-quality, on-time deliverables while aligning priorities and resources to maximize program value and proactively resolve critical challenges. Anticipate operational and strategic risks, establish contingency plans, and pressure-test assumptions, timelines, and budgets to maintain program agility and informed decision-making. Serve as the primary liaison between the Core Team and governance committees, presenting program materials with clear, data-driven recommendations and actionable options to support timely approvals. Build, influence, and sustain high-performing teams, guiding complex, high-stakes decisions without direct authority. Lead cross-functional teams to deliver high-impact program outcomes, challenging assumptions, timelines, and budgets while developing alternative scenarios to mitigate risk and maximize value. Own the quality, integrity, and timeliness of team outputs, ensuring company-level decisions are informed by robust, high-caliber data; set pace and priorities to achieve milestones in a highly competitive landscape. Serve as the program spokesperson, aligning stakeholders and communicating strategy, progress, and decisions clearly across internal and external audiences. Inspire innovation, scientific rigor, and creative problem-solving, fostering a culture of collaboration, continuous improvement, and boundary-less thinking. Coach and develop team members to achieve peak performance, cultivating accountability, skill growth, and collective achievement. Lead with pragmatism and clarity through ambiguity, charting the path forward and driving complex drug development decisions in fast-paced, dynamic environments. Travel up to 20% It is imperative that REGENXBIO employees embody our core values by working collaboratively, building strong relationships and using clear communication to meet shared objectives. What we're looking for Bachelor’s degree required; advanced degree (MS, PhD, MBA) in life sciences or healthcare field preferred. Proven leader with 8+ years in pharmaceutical industry leadership, with a strong track record driving drug development programs through pivotal stages to commercialization; product launch and early commercialization experience is a strong plus. Strong understanding of drug development and commercialization processes, ideally within rare disease or gene therapy Deep knowledge of neuromuscular diseases is highly desirable. The ability to work well under intense pressure, tight timelines, and in rapidly changing situations Evidence of an entrepreneurial spirit and a capacity to find creative solutions to unexpected hurdles Interacts effectively across teams with supporting REGENXBIO functions and disciplines using influencing, communication and relationship building skills Commitment to anticipate, influence and direct change Excellent listening and collaboration skills Why should you apply? By joining REGENXBIO, you will have the opportunity to be a part of a growing company, with an incredible team, who is passionate about developing novel AAV gene therapies for patients in need. We offer a comprehensive and competitive benefit & compensation package which includes market-competitive salaries, an annual bonus program, education assistance, retirement plan with employer match, stock options at all levels, summer hours and more! The estimated compensation range for this role is $235,000 to $335,000 annually. The actual salary offered to the final candidate depends on a number of factors such as relevant work experience, skills, education, and years of experience. In addition, professional development is important to us. By joining our team, you’ll have the opportunity to be exposed to challenging projects and have access to development resources to help you grow personally and professionally. #J-18808-Ljbffr Regenxbio