Principal ML Engineer

Thank you for your interest in joining Solventum. Solventum is a new healthcare company with a long legacy of solving big challenges that improve lives and help healthcare professionals perform at their best. At Solventum, people are at the heart of every innovation we pursue. Guided by empathy, insight, and clinical intelligence, we collaborate with the best minds in healthcare to address our customers' toughest challenges. While we continue updating the Solventum Careers Page and applicant materials, some documents may still reflect legacy branding. Please note that all listed roles are Solventum positions, and our Privacy Policy: applies to any personal information you submit. As it was with 3M, at Solventum all qualified applicants will receive consideration for employment without regard to their race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Job Description:

Principal ML Engineer

3M Health Care is now Solventum

At Solventum, we enable better, smarter, safer healthcare to improve lives. As a new company with a long legacy of creating breakthrough solutions for our customers' toughest challenges, we pioneer game-changing innovations at the intersection of health, material and data science that change patients' lives for the better while enabling healthcare professionals to perform at their best. Because people, and their wellbeing, are at the heart of every scientific advancement we pursue.

We partner closely with the brightest minds in healthcare to ensure that every solution we create melds the latest technology with compassion and empathy. Because at Solventum, we never stop solving for you.

The Impact You'll Make in this Role

As a Principal ML Engineer , you will lead the technical architecture and engineering strategy for integrating sophisticated AI into high-stakes Healthcare Information Systems (HIS). We are looking for a seasoned builder who prioritizes reliability, system performance, and automated scalability over hype.

While many focus on the "science" of modeling, your mission is the engineering of the ecosystem . You will architect the robust MLOps pipelines and cloud infrastructure required to move models from experimental notebooks into mission-critical clinical environments. You are the bridge between raw data and resilient, production-grade AI services.

Key Responsibilities

1. MLOps & System Architecture

• Production Lifecycle: Lead the design and implementation of end-to-end ML lifecycles, focusing on automated CI/CD pipelines, model versioning (MLflow/DVC), and reproducible experimentation.
• Inference at Scale: Architect high-performance serving layers for both LLMs and classical models, ensuring low-latency and high-availability in a secure healthcare cloud environment.
• Agentic Orchestration: Build the underlying infrastructure for agent-based reasoning systems, ensuring these "Agentic" workflows are traceable, auditable, and integrated into existing HIS.

2. Data Engineering & Infrastructure

• Data Reliability: Design robust data pipelines (ETL/ELT) to process healthcare-specific formats (FHIR, HL7, DICOM) into high-quality features for real-time and batch inference.
• Hybrid Infrastructure: Manage and optimize cloud-native infrastructure (AWS/Azure/GCP) using Infrastructure as Code (Terraform/Pulumi) to support heavy compute workloads.
• System Integrity: Implement comprehensive monitoring and observability frameworks to detect data drift, model decay, and system bottlenecks before they impact clinical outcomes.

3. Technical Leadership & Governance

• Engineering Authority: Serve as the lead architect for the ML platform, ensuring all systems are HIPAA/HITRUST compliant and follow "security-by-design" principles.
• Operational Excellence: Establish rigorous standards for code quality, containerization (Docker/Kubernetes), and system documentation across the engineering organization.
• Strategic Mentorship: Elevate the team by fostering a culture of "ML as Engineering," guiding junior engineers in building maintainable, modular, and scalable software.

Your Skills and Expertise
To set you up for success in this role from day one, Solventum requires (at a minimum) the following qualifications:

• Bachelors Degree or Higher in Computer Science, Software Engineering, or a related technical field.
• 10+ years of experience in software engineering, with at least 6 years dedicated to deploying and maintaining large-scale ML systems in production (not just research or POCs).

AND

• MLOps & Cloud: Expert-level experience with Cloud Providers (AWS/GCP/Azure) and orchestration tools (Kubernetes, Kubeflow, or Airflow).
• Engineering & Programming: Expert-level Python and Java/Go (or similar). Deep proficiency in backend frameworks and system design patterns.
• Data Engineering: Strong experience with Spark, Snowflake/Databricks, and building scalable feature stores.
• Applied AI: Hands-on experience deploying Generative AI (LLMs) and Agentic frameworks (LangChain/LangGraph) within a containerized microservices architecture.

Additional qualifications that could help you succeed even further in this role include:

• Hardware Optimization: Experience with GPU optimization, quantization, or specialized serving frameworks (vLLM, TGI).
• Master's or PhD in Computer Science, Software Engineering, or a related technical field is preferred
• Security & Compliance: Deep understanding of cybersecurity best practices within regulated industries (Healthcare, Finance, or Defense).
• Distributed Systems: Proven ability to design systems that handle massive concurrency and distributed data processing.

Work location:

• Remote

Travel: May include up to 10% domestic

Must be legally authorized to work in country of employment without sponsorship for employment visa status (e.g., H1B status).

Supporting Your Well-being


Solventum offers many programs to help you live your best life - both physically and financially. To ensure competitive pay and benefits, Solventum regularly benchmarks with other companies that are comparable in size and scope.


Onboarding Requirement: To improve the onboarding experience, you will have an opportunity to meet with your manager and other new employees as part of the Solventum new employee orientation. As a result, new employees hired for this position will be required to travel to a designated company location for on-site onboarding during their initial days of employment. Travel arrangements and related expenses will be coordinated and paid for by the company in accordance with its travel policy. Applies to new hires with a start date of October 1st 2025 or later.

Responsibilities of this position include that corporate policies, procedures and security standards are complied with while performing assigned duties.

Solventum is committed to maintaining the highest standards of integrity and professionalism in our recruitment process. Applicants must remain alert to fraudulent job postings and recruitment schemes that falsely claim to represent Solventum and seek to exploit job seekers.

Please note that all email communications from Solventum regarding job opportunities with the company will be from an email with a domain of @solventum.com . Be wary of unsolicited emails or messages regarding Solventum job opportunities from emails with other email domains.

Please note, Solventum does not expect candidates in this position to perform work in the unincorporated areas of Los Angeles County.

Solventum is an equal opportunity employer. Solventum will not discriminate against any applicant for employment on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, or veteran status.

Please note: your application may not be considered if you do not provide your education and work history, either by: 1) uploading a resume, or 2) entering the information into the application fields directly.

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