Senior Principal Scientist, ADME-PK - PK Translation Lead
$196k - $240kDyne Tx
Dyne Tx, located in Waltham, MA, is searching for a Senior Principal Scientist in ADME/PK to lead preclinical strategies for drug candidates. The role involves designing studies to understand pharmacokinetics, collaborating with multiple departments, and authoring regulatory submissions. Candidates should have a PhD and over 12 years of relevant experience, with a strong background in drug metabolism and pharmacokinetics. The position offers a salary range of $196,000 to $240,000 and is onsite only. #J-18808-Ljbffr
$196k - $240k
...follow us on X, LinkedIn and Facebook. Role Summary: The Senior Principal Scientist, ADME/PK leads preclinical PK and ADME strategy for Dyne’s drug... ...and executes internal and external studies, develops translational PK and modeling approaches to support clinical dose projections...PrincipalSeniorLocal area$138.6k - $257.4k
...Senior Principal Scientist / Associate Director, PK Sciences, Therapeutic Areas (DUAL LEVEL POSTING... ...to develop and implement translational or clinical pharmacology... ...disciplines, Drug Disposition (ADME, BA), Modeling &... ...agencies, as appropriate Lead a PK Science Subteam with...PrincipalSenior$148k - $203.5k
Principal Scientist / Senior Principal Scientist, Bioanalysis Bioanalytical Lead | Drug Metabolism & Pharmacokinetics Note: Level will be commensurate with experience... ...be expected to serve as operations lead for ADME and PK studies as needed. The ideal candidate...PrincipalSeniorFull time- Novartis Farmacéutica is looking for a PK Sciences project team representative in Cambridge or San Diego, focusing on developing translational pharmacology strategies for late clinical development. The role requires a Ph.D./Pharm.D., with skills in pharmacokinetics and...Senior
- Monte Rosa Therapeutics, Inc is looking for an experienced DMPK and ADME Scientist to lead efforts in drug discovery and development. The successful candidate will collaborate across teams to ensure optimal drug pipeline progression, overseeing all aspects of DMPK assessments...Suggested
$138.6k - $270.4k
Novartis Farmacéutica in Cambridge is seeking a Senior Principal Scientist / Associate Director to join their PK Sciences team. The ideal candidate will lead cross-functional project teams to develop innovative pharmacological strategies for new medicines across various...Senior$194.71k - $235.94k
...motivated, exceptional scientist to join our Drug... .... The role is a senior scientific leader... ...strategic leadership in ADME, pharmacokinetics, PK/PD, and translational science,... ...Responsibilities Lead DMPK strategy for... ...R1603125 : Senior Principal Scientist - DMPK Project...PrincipalSeniorHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work- ..., and scientifically rigorous Scientist/Senior Scientist with deep expertise... ...renal disease mechanisms, and translationally relevant kidney disease models to build and lead our kidney biology engine at a... ...functional knockdown. In vivo PK/PD, biodistribution, efficacy,...Senior
- ...highly motivated and experienced Scientist/Senior Scientist to join a... ...Responsibilities Build and lead the internal kidney biology... ...functional knockdown In vivo PK/PD, biodistribution, efficacy... ...Design mechanistic assays and translational studies for kidney disease pathways...Senior
- ...Zealand Pharma U.S., Inc. in Cambridge, Massachusetts, is looking for a Principal or Senior Principal Scientist to lead protein drug discovery for next-generation biologics. This role involves defining strategy and driving programs from idea through lead‑candidate selection...PrincipalSenior
$140.3k - $189.7k
Alnylam Pharmaceuticals in Cambridge, MA is seeking a Sr. Scientist in Clinical Pharmacology to support an expanding clinical portfolio... ...skills using tools such as R and Phoenix. Responsibilities include leading analyses, providing regulatory input, and collaborating closely...SeniorTemporary work- ...A biotechnology company in Massachusetts is looking for a Senior Principal Scientist/Associate Director in toxicology to support nonclinical safety strategies for Degrader-Antibody Conjugate (DAC) programs. The position involves designing and overseeing toxicology studies...PrincipalSenior
$184.5k - $321.2k
Dormont Manufacturing Co is seeking a dedicated scientist in Boston, MA to innovate in the field of genetic medicines. This full-time position emphasizes leadership in ADME studies and requires a Ph.D. in a related scientific field with over five years of experience in...Full time- ...Senior Scientist/Principal Scientist, Bioinformatics, within the Data Science team. The role involves... ...phosphoproteomics AP3 platform. Position Overview Lead the analysis of large‑scale proteomics... ..., biology, and biomarker teams to translate analytic findings into actionable...PrincipalSeniorLocal area
- Treeline in Watertown, MA is looking for a Senior Manager, Clinical Data Management who will oversee data management from startup through... .... You will collaborate with CROs, manage external vendors, and lead process optimization efforts. The ideal candidate has 8+ years...PrincipalSenior
- ...seeking a highly experienced toxicology scientist to support and drive nonclinical safety... ...submissions, operating at the Senior Principal Scientist / Associate Director level and... ...assessments. Serve as the nonclinical toxicology lead on assigned DAC programs, providing...PrincipalSenior
- Vertex Pharmaceuticals is seeking a Modeling & Simulations Scientist II to lead high-quality PK/PD programming and manage programming deliverables for studies. The role involves ensuring quality in datasets, developing automated solutions, and guiding a team of programmers...Remote jobFlexible hours
$85k - $105k
...Boston IVF is seeking a Senior Embryologist to join our Waltham, MA laboratory team. The ideal candidate will have a Bachelor of Science degree in a related field and over 3 years of experience in human IVF laboratory work in the U.S. Responsibilities include performing...SeniorFull time$128.6k - $210k
Regeneron Pharmaceuticals, Inc is seeking a Senior Clinical Pharmacologist to lead the planning and analysis of pharmacokinetic studies. The ideal candidate will hold a PhD in relevant fields and have at least 3 years of clinical pharmacology experience. This role involves...Senior$120k - $160k
...clinical trials and are proud to be a part of the process that leads to new cures. WORKING AT GENEZEN Many people have... ...and you can be part of that team. JOB SUMMARY The QC Senior/Principal Scientist for Analytical Method Validation is key role within our Quality...PrincipalSeniorLive inImmediate startVisa sponsorship$220k - $270k
...Zealand Pharma U.S., Inc. in Cambridge is seeking a Principal or Senior Principal Scientist for Peptide & Bioconjugate Drug Discovery. This role involves leading the development of peptide drug discovery capabilities, with significant responsibilities for strategy and...PrincipalSenior- ...A leading biotechnology company in Bedford, Massachusetts, is seeking a (Senior) Principal Scientist in Cell Therapy. This hands-on role involves significant leadership in cell therapy discovery and development, advancing programs from early discovery to IND-enabling...PrincipalSenior
- ...A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of...PrincipalSenior
- ...biopharmaceutical company is looking for a Senior Principal Scientist to join their Neuromuscular group in... ..., MA. The ideal candidate will lead drug discovery efforts focusing on muscle... ...discovery, with a strong emphasis on translational biology. This position offers a...PrincipalSeniorWork at officeRemote work
$177k - $308k
...models across key ADMET and PK/PD endpoints (clearance, permeability... ...for partner use. Develop translational modeling approaches (PBPK,... ...coaching/mentorship to junior scientists and help grow TuneLab’s ADMET... ...years relevant experience in ADME/PKPD, Pharmacometrics,...SeniorFull timeFlexible hours- ...Novartis Farmacéutica is seeking a Principal Scientist, ADPKD Biology Lead to shape and execute the discovery biology strategy for renal programs. This senior lab-embedded role involves translating insights from genetics into actionable targets and leading programs through...Principal
$120 - $140 per hour
A leading provider in pharmaceutical research is seeking a Senior Scientist to act as a DMPK project representative. The role involves providing scientific leadership... ...will have extensive experience in ADME principles and PK/PD modeling, strong communication skills, and...Hourly payContract work- ...A global biopharmaceutical company is seeking a Senior Principal Scientist to lead drug discovery efforts in muscle biology. The position emphasizes... ...junior scientists, managing projects, and advancing translational research. Candidates should possess a PhD with 15+ years...PrincipalSeniorWork at officeRemote work
$168k - $220.5k
...A global biopharmaceutical company is seeking a Senior Principal Scientist who will lead drug discovery efforts in muscle biology. The successful candidate will manage multiple projects and supervise junior scientists. A strong background in biology and drug discovery...Principal- ...Exponent Inc. is looking for a Principal Scientist to join their Health Sciences Practice in Natick, MA. This role involves providing expert guidance on projects related to medical evaluations, risk assessment, and causation analysis. The ideal candidate will have an M...Principal
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