Principal Scientist/Director, Translational Pharmacology
5AM Ventures
Job Description
Job Description
We are seeking a highly motivated, hands-on Director of Translational Pharmacology to lead and drive preclinical pharmacology efforts across our pipeline. This individual will play a central, decision-making role in translating innovative science into rigorous, in vivo proof-of-concept and clinically actionable pharmacology strategies.
Qualifications- PhD, MD, or equivalent in pharmacology, biomedical sciences, or related field
- Significant experience in preclinical pharmacology within biotech or pharmaceutical settings
- Experience in choosing appropriate animal models
- Deep expertise in PK/PD modeling, with strong grounding in chemical kinetics and quantitative biology
- Proven experience designing studies to evaluate drug combinations and synergy, including application of factorial experimental design Demonstrated experience designing and interpreting in vivo pharmacology studies
- Experience in advancing preclinical candidates through IND-enabling studies and contributing meaningfully to IND submissions
- Strong statistical and data analysis skills
- Experience in metabolic diseases, particularly obesity and/or diabetes, strongly preferred
Final compensation will be based on a candidate’s qualifications, experience, and geographic location. Employees are also eligible for performance bonuses, equity participation and comprehensive health benefits.
We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
Vacancy posted a month ago
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