Principal ML Scientist
$231k11105 Expedia, Inc.
Principal Machine Learning Scientist, GenAI Position within Expedia’s Traveler & Partner Service Platform (TPSP) Product & Technology organization, which builds the core capabilities and experiences that power customer service across the Expedia ecosystem. Responsibilities Define and lead the ML strategy for one or more complex product or platform areas (e.g., personalization, search & recommendations, pricing, fraud/risk, or generative AI–powered experiences). Formulate ill‑defined business problems into well‑posed ML problems, selecting appropriate modeling approaches and success metrics. Design and implement state‑of-the‑art ML models (e.g., deep learning, representation learning, causal inference, bandits, LLM/GenAI where appropriate) and own them through production. Partner closely with engineering to productionize models, improve data and feature pipelines, and ensure reliability, latency, and scalability requirements are met. Lead experiment design and evaluation, including A/B tests and offline evaluations; drive decisions with rigorous statistical analysis. Proactively identify opportunities where ML can unlock new customer and business value, build business cases, and influence product and leadership roadmaps. Establish and champion best practices for model development, evaluation, monitoring, and responsible AI (fairness, robustness, privacy, and safety). Provide technical leadership and mentorship to other ML scientists, data scientists, and ML engineers through design reviews, pairing, and informal coaching. Communicate complex technical topics in clear, concise ways to executives, product leaders, and non‑technical stakeholders, influencing direction across teams and organizations. Collaborate with platform and infra teams to evolve ML tools, feature stores, experimentation platforms, and model monitoring capabilities. Minimum Qualifications Bachelor’s degree in Computer Science, Statistics, Applied Mathematics, Electrical Engineering, or a related technical field (or equivalent practical experience). 10+ years of experience in applied ML / data science, including significant experience owning production models in complex domains. Deep expertise in machine learning algorithms and statistical modeling, such as gradient‑boosted trees, deep learning, representation learning, or similar. Strong Python skills and experience with major ML libraries and frameworks (e.g., PyTorch, TensorFlow, JAX, scikit‑learn) and data tools (e.g., Spark, SQL). Proven track record of shipping production ML systems at scale and driving measurable product or business impact. Experience designing and interpreting experiments (A/B tests), with solid grounding in statistics (estimation, hypothesis testing, causal inference basics). Demonstrated ability to lead cross‑functional initiatives with product, engineering, and business partners, without formal authority. Excellent communication skills, with the ability to explain complex ML concepts to diverse audiences and drive alignment. Preferred Qualifications Advanced degree (MS or PhD) in Computer Science, Machine Learning, Statistics, Operations Research, or a related quantitative field. Experience in one or more relevant domains, such as personalization, search & recommendations, ranking or relevance; marketplace optimization, pricing, or yield management; fraud/risk modeling, anomaly detection; natural language processing / LLMs / generative AI. Experience architecting end‑to‑end ML systems: data/feature pipelines, model training, evaluation, deployment, and monitoring in distributed environments. Demonstrated impact in technical leadership: setting standards, influencing roadmaps across teams, and mentoring senior ICs. Familiarity with MLOps practices and platforms (feature stores, CI/CD for models, model monitoring & alerting). Publications in top‑tier ML/AI conferences or journals, or equivalent evidence of thought leadership (talks, patents, open‑source). Salary The total cash range for this position in Seattle is $231,000.00 to $323,500.00. Employees in this role have the potential to increase their pay up to $369,500.00, which is the top of the range, based on ongoing, demonstrated, and sustained performance in the role. Starting pay will vary based on multiple factors, including location, available budget, and an individual’s knowledge, skills, and experience. Pay ranges may be modified in the future. Benefits Medical, dental, and vision coverage. Paid time off and other vacation benefits. Employee Assistance Program. Wellness and travel reimbursement. Travel discounts and International Airlines Travel Agent (IATAN) membership. Accommodation Requests If you need assistance due to a disability or other health conditions, please reach out to our Recruiting Accommodations Team through the Accommodation Request portal. EEO Statement Expedia is committed to creating an inclusive work environment with a diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, or any other characteristic protected by law. This employer participates in E‑Verify. #J-18808-Ljbffr 11105 Expedia, Inc.
- A leading automation company seeks a Principal Applied Scientist in Bellevue, WA. The role involves defining technical strategies for agent-based automation, deploying ML systems, and mentoring teams in cutting-edge AI technologies. The ideal candidate has an advanced degree...Principal
- ...Principal Machine Learning Scientist, GenAI This role sits within Expedia's Traveler & Partner Service Platform (TPSP) Product & Technology organization... ...Expedia travelers and partners, with strong traditional ML based personalization skills along with Agentic AI...Principal
$231k
...career journey. We’re building a more open world. Join us. Principal Machine Learning Scientist, GenAI This role sits within Expedia’s Traveler &... ...Expedia travelers and partners, with strong traditional ML based personalization skills along with Agentic AI skillsets...PrincipalLocal areaFlexible hours$164k - $261.5k
...intelligence. This role requires 10+ years in data science, partnership with executive leadership, and the ability to develop innovative ML models. Responsibilities include strategic leadership, data analysis, and continuous innovation in AI trends. The position offers a...Principal$164k - $261.5k
...predictive models and insights. The ideal candidate will have over 10 years in data science, strong communication skills, and experience with ML frameworks. Offering a salary between $164,000 and $261,500, the position includes various benefits such as medical and retirement...Principal$197.3k - $313.7k
...over 10 years of experience in data science, with strong skills in Python, R, and SQL. You will partner with executives to leverage ML models for organizational growth. The role offers a base salary range of $197,300 to $313,700, along with comprehensive benefits including...Principal- Bristol Myers Squibb is seeking a Senior Principal Scientist in Seattle to lead a team in molecular biology analytical methods for cell therapy. The role involves designing, executing, and interpreting scientific programs while ensuring compliance with regulatory standards...Principal
$228k - $342k
...the Workday platform. About The Role As a Principal AI Researcher, you will be a technical... ...Workday AI Research Team. This is a role for a scientist‑leader who thrives on defining the... ...Qualifications 8+ years of experience in AI/ML research or applied science, with a...PrincipalWork at officeRemote workHome officeFlexible hours- Vertex Pharmaceuticals Incorporated is seeking a Senior Principal Research Scientist to lead the clinical biomarker strategy for various programs. The role involves overseeing assay development, ensuring regulatory compliance, and working with internal and external teams...Principal
$110k - $120k
120 Altasciences Preclinical Seattle LLC is looking for an experienced LC-MS Principal Research Scientist to lead GLP bioanalytical study method development and validation. The role includes collaborating with other scientists, performing laboratory analyses, and ensuring...PrincipalRemote job$250k - $300k
Principal AI Researcher (Agentic Systems & AI Infrastructure) Seattle, WA or McLean, VA or Remote About Us Red Cell Partners is an incubation... .... Responsibilities Define and evolve the long-term AI/ML research strategy and technical roadmap for Trase OS in alignment...PrincipalRemote workShift work$224k - $336k
...Job Description and Requirements ABOUT THE ROLE As a Principal Applied Scientist, Reliability, you will lead the design and validation of... ...Python programming skills and experience with common data and ML libraries such as numpy, PyTorch, scikitlearn, and PySpark...PrincipalRemote work- The Walt Disney Company (Germany) GmbH is looking for a Senior Principal Machine Learning Engineer to lead and mentor teams in Seattle. This role focuses on applying sophisticated machine learning and AI techniques to improve ad technologies. The ideal candidate will have...Principal
- Description Position Overview: As a Decision Scientist within the Data & Analytics organization, you will collaborate with cross‑functional teams to measure agentic impact, influence leaders with in‑depth analysis, and strategically partner with Product Managers to shape...Principal
$173k - $242.5k
PowerToFly is seeking a Senior Machine Learning Scientist to develop innovative machine learning solutions for personalization in Seattle. This role involves designing and applying machine learning systems to enhance traveler experiences. The ideal candidate has 8+ years...- Carnegie Mellon University seeks a Senior Machine Learning Research Scientist to focus on vulnerabilities of AI and ML algorithms, securing them against attacks. You will lead research, investigate emerging technologies, and collaborate with a diverse team. Applicants...
- Traveltechessentialist is seeking a Principal Machine Learning Scientist to drive AI initiatives within the organization. This role involves defining ML strategies and implementing cutting-edge models to transform customer experiences across platforms. Your leadership...
- Axon is seeking a skilled Senior Research Scientist to join our AI team in Seattle. You will develop AI solutions for public safety, collaborating with cross-functional teams. The role emphasizes innovation in computer vision and machine learning, contributing to the company...
$152.82k - $185.18k
Senior Principal Scientist, Drug Product Analytical Science and Technology (ASAT), Cell Therapy Req Number: R1602888 • Updated: 2026-05-30 • Location: Seattle, 400 Dexter-WA Position Summary This technical leadership role is a highly experienced subject matter expert in...PrincipalHourly payFull timeSummer workFlexible hours- ...category of energy that outperforms traditional sources on both environmental impact and cost. What you'll be doing As the Principal Geologist at Endurance, you'll be at the forefront of identifying and characterizing the most promising subsea geothermal sites...Principal
- ...leading technology firm based in Seattle is seeking a Senior Research Scientist focused on computer vision and machine learning. In this role,... .... The ideal candidate has a PhD and experience in the ML lifecycle. This position offers a competitive salary and a hybrid...
$173k - $242.5k
NLP PEOPLE is seeking a Senior Machine Learning Scientist in Seattle to lead the development of GenAI and LLM solutions, enhancing customer... ...experiences post-booking. The role involves managing end-to-end ML projects, applying advanced techniques in machine learning and...$173k - $242.5k
Expedia, Inc. is looking for a machine learning scientist in Seattle to define the roadmap for CRM personalization using ML. This role involves building and owning production ML systems while mentoring junior scientists. Candidates should have a Master’s or PhD in a related...$173k - $242.5k
11105 Expedia, Inc. is seeking a Senior Machine Learning Scientist located in Seattle. You will design and implement sophisticated ML solutions that drive business improvements. The ideal candidate possesses a PhD or Master's degree, with a strong background in machine...$173k - $242.5k
Traveltechessentialist is seeking a machine learning scientist to lead production ML systems that enhance CRM personalization. You will help shape the ML science roadmap, partner across marketing and analytics, and communicate findings to stakeholders. Ideal candidates...- Expedia, Inc. in Seattle is seeking a Machine Learning Scientist to build and manage innovative ML systems for personalized CRM offers. This role involves defining the ML roadmap, collaborating across teams, and driving effective measurement strategies. The ideal candidate...Flexible hours
$137.5k - $192.5k
Expedia, Inc. is seeking a Machine Learning Scientist III in Seattle to enhance a pricing system that impacts billions in revenue. The role involves designing robust ML models, developing data pipelines, and collaborating with cross-functional teams. Minimum qualifications...$137.5k - $192.5k
Traveltechessentialist seeks a Machine Learning Scientist III to design and implement ML solutions aimed at optimizing pricing systems. Candidates should have a bachelor's degree in a related field and extensive experience in ML model development. This role offers a pay...Flexible hours- Disney Cruise Line - The Walt Disney Company is seeking a seasoned Software Engineer to lead advancements in ad technology. This role involves collaborating across teams, mentoring peers, and optimizing foundational architecture for Disney's media platforms. Candidates ...Principal
$140k - $175k
...ensure success on the Outreach platform, and optimizing machine learning models. Candidates should have at least 2 years of experience in ML, strong programming skills in Python or Java, and a Master's degree or PhD in relevant fields. The offered salary ranges from $140,00...Flexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal ML Scientist. Be the first to apply!
- principal applied scientist Seattle, WA
- image scientist Seattle, WA
- scientist Seattle, WA
- research scientist machine learning deep learning Seattle, WA
- deep learning scientist Seattle, WA
- senior principal scientist Seattle, WA
- machine learning scientist Seattle, WA
- scientist immunology Seattle, WA
- safety scientist Seattle, WA
- downstream processing scientist Seattle, WA

