Associate Director, Internal Audit

Job Description General Summary: The Associate Director of Internal Audit will support the development and execution of a risk-based audit plan to evaluate and improve the effectiveness of Vertex’s risk management, control, and governance processes. Reporting to the VP, Chief Audit Executive (CAE), this role will assist in implementing departmental strategy, contributing to annual functional goals, and overseeing portions of the SOX testing program. Key Duties and Responsibilities: Maintain strong knowledge of Vertex’s core business and assist in developing a risk and control assurance program aligned with company objectives and risk appetite. Contribute to the development of departmental strategy, Audit Committee reporting, and departmental initiatives such as data analytics, trend reporting, etc. Build collaborative relationships with Vertex leaders to promote understanding of risk, control, and governance. Direct project team (Managers, Supervisors, Staff) in the performance of audits (and special requests such as investigations) and oversee execution of assigned portion of audit plan. Ensure project planning, fieldwork and reporting are of high quality and in accordance with professional and departmental standards. Critically evaluate issues identified during audit process and corresponding business risk. Develop recommendations to enhance controls and partner with the business to develop workable solutions. Provide coaching and development to junior team members; may have limited supervisory responsibilities. Identify, develop, and implement improvements in departmental practices (reporting, policies, procedures, audit programs, computerized applications, etc.) Contribute to improvements in departmental practices, including reporting, policies, and audit programs. Coordinate internal audit work performed by third-party providers as needed. Assist in driving efficiency in SOX testing and support external auditor reliance. Knowledge and Required Skills: Ability to analyze pharmaceutical/biotech processes and recommend control improvements. Strong verbal and written communication skills; able to influence and collaborate effectively. Organized, deadline-driven, and adaptable in a dynamic environment. Solid understanding of auditing concepts and ability to apply them to complex scenarios. Proficiency in interacting with management and external auditors. Education and Experience: Bachelor's degree in accounting or related discipline; MBA preferred. CPA required. Typically requires 8+ years of progressive audit experience or equivalent combination of education and experience. Experience in financial, operational, compliance, and forensic audits. “Big 4” accounting firm and industry experience (Pharma/Biotech) preferred. Prior experience mentoring junior staff. Why Vertex At Vertex, we bring together the brightest minds to tackle the toughest challenges in medicine. Our culture is rooted in innovation, collaboration, and a relentless commitment to transforming lives. We empower our employees to make an impact while growing their careers in an inclusive, dynamic environment. How You’ll Succeed Demonstrate curiosity and adaptability in a fast-paced environment. Build strong partnerships across the business to drive meaningful change. Apply critical thinking and problem-solving skills to complex challenges. Embrace Vertex’s core values: Innovation, Integrity, Collaboration, and Patient-Centricity. #HYBRID #LI-MF1 Pay Range: $148,800 - $223,200 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.