IT Principal Business Application Architect

IT Business Applications Architect
Billerica, MA (Hybrid)


Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its proprietary Simoa technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue-advancing precision medicine from discovery to diagnostics.


ROLE SUMMARY:
Quanterix is seeking a Principal Business Applications Architect (Systems) to lead the strategy, design, and transformation of our enterprise applications landscape.
This is a high-impact role responsible for shaping how our core platforms-including Infor Syteline 10, Salesforce Sales Cloud, Salesforce Service Cloud, Pardot, Tableau, and Microsoft Power BI-operate today, while architecting our transition to Oracle Fusion Cloud over the next 12-18 months.
You'll operate as a Principal-level individual contributor, partnering directly with executive leadership to align technology, data, and business processes to enable scale, efficiency, and growth.


WHAT YOU'LL DO:


* Own the Business Architecture Landscape for business applications across ERP, CRM, and analytics
* Lead the end-to-end architecture and migration strategy to Oracle Fusion Cloud
* Drive Business Process Engineering & Re-Engineering (BPE/BPR) across Finance, Supply Chain, Sales, Service, and Marketing
* Design scalable, integrated solutions across Salesforce and ERP ecosystems
* Establish architecture standards, governance, and integration patterns
* Partner with business leaders to translate strategy into systems and process solutions
* Enable data-driven decision making through strong data and analytics architecture
* Mentor internal teams and influence system integrators and vendors


BASIC QUALIFICATIONS:


* 15+ years of related experience with a Bachelor's Degree in Computer Science, Information Systems / Information Technology , Software Engineering or Business Administration (with a focus on Information Systems or Operations.
* 12 years + experience with a Masters Degree in Information Systems / Information Technology, Computer Science or Business Administration (MBA, especially with Operations, Strategy, or Technology focus.

• 12+ years of experience in Enterprise or Solutions Architecture

PREFERRED QUALIFICATIONS:

• Experience with Oracle Fusion Cloud implementations
• Background in Life Sciences, Diagnostics, or Healthcare
• Familiarity with regulated environments (FDA, SOX)
• Certifications (TOGAF, Salesforce Architect, Oracle Cloud)
• Proven success leading ERP transformations (Oracle, SAP, or similar)
• Strong experience with Salesforce ecosystem and enterprise BI tools
• Deep expertise in Business Process Engineering and Re-Engineering
• Experience designing end-to-end, integrated enterprise solutions
• Strong knowledge of integrations (APIs, middleware, iPaaS) and data architecture
• Ability to influence senior stakeholders and drive cross-functional alignment

EXPECTATIONS, COMPETENCIES, SKILLS & ABILITIES:

• Billerica, (Hybrid)
• Travel 10 %
• Strategic thinking with the ability to align enterprise systems to business growth and operational efficiency
• Ability to simplify complex system landscapes and communicate effectively with non-technical stakeholders
• Strong collaboration and influencing skills across Finance, Commercial, Manufacturing, and Scientific teams
• Problem-solving mindset with focus on scalable, integrated solutions
• Ability to manage competing priorities in a fast-paced, evolving environment
• Attention to detail with a strong focus on data integrity and system reliability
• Continuous improvement mindset with focus on automation and optimization
• High ownership and accountability for architectural decisions and outcomes

WHY YOU'LL LIKE WORKING WITH US:


Our Opportunity

• Lead a high-visibility enterprise transformation initiative
• Work directly with executive leadership to shape technology strategy
• Drive both systems and business process innovation
• Join a mission-driven company advancing breakthrough diagnostic technologies

Our Technology :
From discovery to diagnostics, Quanterix's ultrasensitive biomarker detection is fueling breakthroughs only made possible through its unparalleled sensitivity and flexibility. Simoa technology has delivered the gold standard for earlier biomarker detection in blood, serum or plasma, with the ability to quantify proteins that are far lower than the Level of Quantification (LoQ). Our industry-leading precision instruments, digital immunoassay technology and CLIA-certified Accelerator laboratory have supported research that advances disease understanding and management in neurology, oncology, immunology, cardiology, and infectious disease.
Akoya Biosciences, a Quanterix company, is The Spatial Biology Company-bringing tissue context to life through high-resolution, single-cell imaging. Akoya's spatial phenotyping platforms help researchers visualize and measure how cells organize and interact within tissue to influence disease progression and therapeutic response. From discovery through clinical research, Akoya offers a full continuum of solutions, including PhenoCycler, PhenoImager Fusion and HT, and PhenoCode Panels. As part of Quanterix, Akoya complements a leading portfolio of ultra-sensitive biomarker detection technologies, together enabling a more complete view of biology and disease across both tissue and blood.


Our Commitment to Employees:
At Quanterix, our values are based on: Team , Innovation, Customer and Owner .


Team : Challenge assumptions, not the person. Respect diversity of thought and hold ourselves to lofty standards

Innovation : Stay curious, experiment, create and change

Customer : Prioritize and celebrate these pioneers by doing our best to deliver on commitments

Owner: Act with high integrity and in the best interest of Quanterix. Take measured risks and learn from their success and failures.


We reward and recognize our employees by offering competitive compensation and a 401k plan with employer match, as well as competitive health, dental, and vision benefits for employees and their dependents. We also offer an unlimited vacation policy to all exempt employees, and a generous PTO policy for non-exempt employees. All employees are eligible for equity, employee stock purchase plan, a performance bonus, and 1:1 financial counseling/planning. We also offer Tuition Assistance. We have a free, state-of-the-art onsite fitness center for all employees. To keep you fueled up, we provide onsite employees free snacks and drinks every day!


DIVERSE & INCLUSIVE WORKPLACE:


Quanterix is committed to a Diverse and Inclusive workplace. We strive to recruit candidates who will bring inclusive mindsets and contribute to our values.


Quanterix is an Equal Opportunity Employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Quanterix will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.