Senior Global Medical Affairs Leader, Amyloidosis

Senior Global Medical Affairs Leader, Amyloidosis

Location: Gaithersburg, Maryland

AstraZeneca is seeking a Senior Global Medical Affairs Leader, Amyloidosis to help shape ambitious global medical strategy within our CVRM therapy area. This is a highly strategic leadership role for an experienced medical affairs professional who can combine scientific credibility, business leadership, evidence-generation expertise, and strong cross-functional influence to help drive meaningful impact for patients.

Reporting to the Medical Head , the Senior Global Medical Affairs Leader will play a critical role in developing and leading global product and disease area strategies, shaping the market in preparation for launch, advancing high-impact evidence plans, and building strong partnerships across the healthcare ecosystem. The role has broad visibility and influence across AstraZeneca, including collaboration with the Global Medical Team, Global Product Team, Disease Area Teams , and regional and market medical teams.

What You'll Do

In this role, you will lead the development and implementation of global product and disease area medical strategies for amyloidosis . You will work cross-functionally to ensure strategies are translated effectively into regional and country execution, while helping shape clinical practice and support successful launches.

You will design and leverage high-impact evidence-generation activities , including clinical and/or real-world evidence approaches, to support product differentiation, disease area leadership, and practice change. You will help optimize the communication of data and serve as a visible ambassador for practice-changing evidence.

You will act as the voice of Medical , crafting and communicating a compelling scientific and strategic narrative for both product and disease area priorities. This includes influencing internal stakeholders, supporting enterprise alignment, and strengthening AstraZeneca's medical leadership externally.

The role also requires a strong external presence . You will engage with global thought leaders, professional societies, patient organizations, and health systems to identify opportunities for partnership and help improve care for patients. You will be expected to initiate and lead strategic collaborations across the healthcare ecosystem.

Essential Requirements

To be considered for this role, you should bring a doctoral-level degree such as an MD, PhD, or PharmD , along with substantial experience in Medical Affairs leadership within a complex, matrixed environment.

You should have a strong track record as a business leader , with experience such as leading a therapy area or franchise in-market, driving brand performance, or leading large teams and cross-functional strategic initiatives.

You will also need deep understanding of healthcare systems and market shaping , including experience driving transformation programs, building strategic partnerships, or influencing care pathways from a pharmaceutical perspective.

A successful candidate will demonstrate the ability to build internal and external networks across geographies and cultures, and bring substantial expertise in evidence generation , such as Phase II, III, or IV clinical trial experience , real-world evidence , registry strategy , label enhancement , or other practice-changing data generation.

Preferred Qualifications

Experience in CVRM and direct expertise in amyloidosis is strongly preferred. Additional experience in clinical trial protocol development and study delivery would be valuable.

We are also interested in candidates who bring relevant experience beyond Medical Affairs, including work in R&D, Market Access, or Marketing , as well as those who have developed strong relationships with global thought leaders, professional societies, patient organizations, and healthcare organizations .

Experience supporting or leading new product or indication launches , particularly across major geographies such as the US and China , will be viewed favorably.

Why Join AstraZeneca

This is an opportunity to join a team working at the intersection of science, strategy, evidence, and external partnership in a disease area with significant unmet need. You will have the chance to influence global medical strategy, help shape the treatment landscape, and work across the enterprise to support innovation that can improve patient care at scale.

The annual base pay for this position ranges from 243,586.40 - 365,379.60 USD annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.


In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.


Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.


Date Posted
03-Jun-2026

Closing Date
14-Jun-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.